Transaminases persistentemente elevadas - o que fazer?

The persistent hypertransaminasemia requires detailed clinical analyses with history, physical examination and laboratory tests for liver evaluation and differential diagnosis. The purpose of this article is to assist the pediatrician in the management of these cases to optimize the invetigation and diagnosis of these patients. The values of these enzymes can vary according to age group and may be the first manifestation of a liver disease, or metabolic, genetic or extrahepatic disease

Indicações e contra-indicações no transplante hepático pediátrico

Advances in cirurgical techniques and immunessupressores result in better prognosis of patients elected to pediatric liver transplant. Many questions still arise as the transplant indications. Notes that in childhood the liver failure can occur faster than in adults. The main symptons are: progressive cholestasis, encephalopathy, ascites, bleeding of esophageal varices, Hepatopulmonary syndrome, malnutrition, recurrent infections, liver dysfunction, disabling itching and delayed growth and development