1,521 research outputs found
Is rejection a diffuse or localized process in small-bowel transplantation?
Utilization of endoscopy to both visualize and selectively biopsy an intestinal allograft has become the standard for early recognition and treatment of intestinal allograft rejection. Despite the widespread acceptance of the need for selective mucosal biopsies, it has not been shown that the histological features of intestinal allograft rejection are either localized or occur as part of a more diffuse phenomenon within a tubular allograft. To resolve these issues, 88 ileoscopies were performed in 12 small-bowel allograft recipients and mucosal biopsy samples were obtained at 5, 10, and 15 cm, respectively, from the ileal stoma. Each mucosal biopsy was labeled, processed, and evaluated individually for the presence and severity of any evidence for allograft rejection. The data obtained suggest that intestinal allograft rejection is a diffuse process, and biopsies obtained randomly from an ileal graft are likely to demonstrate evidence of allograft rejection when such is present. © 1994 Springer-Verlag New York Inc
Liver transplantation in patients with situs inversus
Two patients with situs inversus and biliary atresia were treated with hepatic transplantation, one with an auxiliary liver and the other with an orthotopic graft which was placed using a piggy-back technique. Both transplants functioned well initially. The auxiliary liver was rejected after 1 1/2 months, and the patient died after an attempt at retransplantation many months later. The recipient of the orthotopic liver has perfect liver function 10 months postoperatively
Successive phase transitions at finite temperatures of the supersolid in the three-dimensional extended Bose-Hubbard model
We study the finite temperature properties of the extended Bose-Hubbard model
on a cubic lattice. This model exhibits the so-called supersolid state. To
start with, we investigate ordering processes by quantum Monte Carlo
simulations, and find successive superfluid and solid phase transitions. There,
we find that the two order parameters compete with each other. We obtain the
finite temperature phase diagram, which contains the superfluid, the solid, the
supersolid and the disordered phase. We develop a mean-field theory to analyze
the ordering processes and compare the result with that obtained by
simulations, and discuss the mechanism of the competition of these two orders.
We also study how the supersolid region shrinks as the on-site repulsion
becomes strong.Comment: 6 pages, 6 figure
Aspergillosis of the CNS in a pediatric liver transplant recipient: Case report and review
A 2-month-old infant who had undergone orthotopic liver transplantation at the age of 2 weeks for carbamoyl phosphate synthetase deficiency developed infection of the CNS due to Aspergillus fumigatus. The patient was successfully treated with administration of a combination of antifungal agents (including intraventricular amphotericin B), drainage of the parietal lobe abscess, and cessation of immunosuppression. An intraventricular catheter was used both to obtain ventricular fluid for microbiologic testing and to deliver amphotericin B during nearly 4 months of treatment. We review literature on aspergillosis in solid-organ transplant recipients, especially those in whom the disease involves the CNS, and discuss in particular clinical presentation, diagnosis, treatment, and outcome
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