ヒト抗酸化酵素グルタレドキシン1（Grx1）による細胞内酸化還元恒常性維持の研究

京都大学新制・課程博士博士(理学)甲第23043号理博第4720号新制||理||1676(附属図書館)京都大学大学院理学研究科生物科学専攻(主査)准教授 秋山 秋梅, 教授 曽田 貞滋, 教授 沼田 英治学位規則第4条第1項該当Doctor of ScienceKyoto UniversityDGA

Financing and Productivity: Evidence from Indian Manufacturing Industry

India grows rapidly in recent years, not to mention its high-technology industry. What are secrets behind this fast-growing situation? This paper intends to find the answer using a firm-level panel data in India and examine the loan-productivity relationship via both contemporaneous and lagged models. I find positive and statistically significant results that loans play an important role in firms’ performances

Nacre-like Aluminium Alloy Composite Plates for Ballistic Impact Applications

It is a major scientific challenge to develop the light-weight materials with high performance simultaneously in diverse applications ranging from civil engineering to defence. Numerical results for composite plates of 5.4-mm, 7.5-mm and 9.6-mm thick bioinspired composite plates were compared with corresponding bulk plates under the impact of a rigid hemi-spherical projectile at same impact velocities. The most significant improvement was recorded for the 5.4-mm thick nacre-like aluminium alloy composite plate, which was attributed to the larger area of plastic deformation due to the tablet arrangement. Experiments data were collected to validate the numerical simulation. It has been found that the nacre-like composites of different thickness had better ballistic behaviour than the bulk ones. The aim of this thesis is to give general background and research progress about natural nacre and the corresponding nacre-inspired artificial composites, to provide the basis for preparing the detailed experimental and numerical study on the ballistic performance of nacre-like aluminium alloy composites. My following ballistic experiments are to validate the numerical simulation results that the nacre-like composite plate has better ballistic performance at high velocity due to the tablets arrangement and plastic deformation. From previous simulation results, 5.4-mm nacre-like plate has shown a significant performance improvement compared with same thickness bulk plate owing to the hierarchical structure induced high energy absorptions. Hence, plate thickness and projectile velocity play a significant role on the performance improvement of the proposed nacre-like AA7075-T651 composites. Further experimental works are needed to assess other crucial parameters for modifying the mechanical behaviours of such bioinspired materials

Sensorial Memories: A Cinema Speculum in Aftersun(2022) and Petite Maman(2021)

In her 1975 article Visual Pleasure and Narrative Cinema, Laura Mulvey used psychoanalysis as a political weapon to critique the issue of the male gaze in traditional Hollywood narrative cinema. Mulvey\u27s work is pioneering for feminist film studies but was criticized and reexamined among film and feminist scholars. Building on the precedent of Mulvey and the feminist research of Luce Irigaray, contemporary scholar Lucy Bolton has proposed the camera as an Irigarayan speculum, explaining how certain contemporary films delve into female characters\u27 inner worlds, creating them with subjectivity and diversity. Drawing on contemporary feminist film theories and phenomenology theories, I argue that women in contemporary films have undergone a transformation from objects to subjects. Through an in-depth analysis of two films released after 2020, Petit Maman (2021) and Aftersun (2022), I will demonstrate how female filmmakers incorporate the Irigarayan speculum into films, exploring female characters\u27 inner worlds and shaping their subjectivity. Both films integrate female characters\u27 memories by breaking linear time, tracing back to their personal history, and validating the diversified shaping process of female characters in body, psyche, and personality while providing audiences with unique viewing experiences. As milestones in contemporary cinema post-2020, these two films affirm the process of women moving toward subjectivity on screen

Cascaded uncoupled dual-ring modulator

We demonstrate that by coherent driving two uncoupled rings in same direction, the effective photon circulating time in the dual ring modulator is reduced, with increased modulation quality. The inter-ring detuning dependent photon dynamics, Q-factor, extinction ratio and optical modulation amplitude of two cascaded silicon ring resonators are studied and compared with that of a single ring modulator. Experimentally measured eye diagrams, together with coupled mode theory simulations, demonstrate the enhancement of dual ring configuration at 20 Gbps with a Q ~ 20,000

Low Latency Computing for Time Stretch Instruments

Time stretch instruments have been exceptionally successful in discovering single-shot ultrafast phenomena such as optical rogue waves and have led to record-speed microscopy, spectroscopy, lidar, etc. These instruments encode the ultrafast events into the spectrum of a femtosecond pulse and then dilate the time scale of the data using group velocity dispersion. Generating as much as Tbit per second of data, they are ideal partners for deep learning networks which by their inherent complexity, require large datasets for training. However, the inference time scale of neural networks in the millisecond regime is orders of magnitude longer than the data acquisition rate of time stretch instruments. This underscores the need to explore means where some of the lower-level computational tasks can be done while the data is still in the optical domain. The Nonlinear Schr\"{o}dinger Kernel computing addresses this predicament. It utilizes optical nonlinearities to map the data onto a new domain in which classification accuracy is enhanced, without increasing the data dimensions. One limitation of this technique is the fixed optical transfer function, which prevents training and generalizability. Here we show that the optical kernel can be effectively tuned and trained by utilizing digital phase encoding of the femtosecond laser pulse leading to a reduction of the error rate in data classification

Suppression of Edge Recombination in InAs/InGaAs DWELL Solar Cells

The InAs/InGaAs DWELL solar cell grown by MBE is a standard pin diode structure with six layers of InAs QDs embedded in InGaAs quantum wells placed within a 200-nm intrinsic GaAs region. The GaAs control wafer consists of the same pin configuration but without the DWELL structure. The typical DWELL solar cell exhibits higher short current density while maintaining nearly the same open-circuit voltage for different scales, and the advantage of higher short current density is more obvious in the smaller cells. In contrast, the smaller size cells, which have a higher perimeter to area ratio, make edge recombination current dominant in the GaAs control cells, and thus their open circuit voltage and efficiency severely degrade. The open-circuit voltage and efficiency under AM1.5G of the GaAs control cell decrease from 0.914V and 8.85% to 0.834V and 7.41%, respectively, as the size shrinks from 5*5mm2 to 2*2mm2, compared to the increase from 0.665V and 7.04% to 0.675V and 8.17%, respectively, in the DWELL solar cells