Scenario Based Municipal Wastewater Estimation: Development and Application of a Dynamic Simulation Model

This paper develops causal loop diagrams and a system dynamics model for estimation of wastewater quantity changes as a function of future socioeconomic development and the municipal water environment of the city under the influence of several key factors. Using Wuhan (a city with population more than 10 million in China) as a case study, the variability of Wuhan’s wastewater quantity and water environment is modeled under different development patterns by year 2030. Nine future scenarios are designed by assigning different values to those key factors, including GDP growth rate, water consumption of annual ten thousand GDP, and wastewater treatment fee. The results show that (1) GDP growth leads to an increase in municipal wastewater quantity, but an increase in wastewater treatment fee can be in favor of reducing urban water pollution, and (2) the impact of per ten thousand yuan GDP water consumption on the amount of municipal wastewater is larger in the near future, while the impact of GDP growth rate is much larger in the long term. The dynamic model has proven to be reliable for simulating the municipal wastewater changes, and it could help decision makers to make the scientific and reasonable decisions

Renal collecting duct carcinoma with extensive coagulative necrosis mimicking anemic infarct: report of a case and the literature review

Collecting duct carcinoma (CDC) with a mass of coagulative necrosis is very rare. We report here a case of CDC with extensive geographic coagulative necrosis mimicking anemic infarct with tumor cells embedded around the necrotic foci in a 73-years-old man. Histopathological examination showed that tumor nests near the necrotic foci were arranged as angulated tubules, tubulopapillary and glandular structures. Neoplastic cells had moderate to abundant eosinophilic cytoplasm and large hyperchromatic nuclei with prominent nucleoli as Fuhrman nuclear grade 3 or 4. The tumor cells were positive for pan-Cytokeratin, Vimentin, E-cadherin, CD10, and CK7, confirming the diagnosis as CDC. The patient is still alive 6 months later from nephrectomy, a long time following up is needed to learn the prognosis. Conclusively, morphology from different portions of the lesion, immunohistochemical stain and the combination analysis of the radiological features is essential to make a precise pathological diagnosis of CDC. And CDC should also be distinguished from clear cell renal cell carcinoma, renal medullary carcinoma, urothelial carcinoma with glandular differentiation, renal neuroendocrine tumor, renal epithelioid angiomyolipoma, renal pigmented paraganglioma and renal mesenchymal chondrosarcoma etc. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/126427052597503

Dysregulation of heat shock protein 27 expression in oral tongue squamous cell carcinoma

<p>Abstract</p> <p>Background</p> <p>Recent proteomic studies identified Hsp27 as a highly over-expressed protein in oral squamous cell carcinoma (OSCC). Clinical studies that attempted to evaluate the prognostic values of Hsp27 yielded inconsistent results, which may be due to inclusion of OSCC cases from multiple anatomic sites. In this study, to determine the utility of Hsp27 for prognosis, we focused on oral tongue SCC (OTSCC), one of the most aggressive forms of OSCC.</p> <p>Methods</p> <p>Archival clinical samples of 15 normal oral tongue mucosa, 31 dysplastic lesions, 80 primary OTSCC, and 32 lymph node metastases were examined for Hsp27 expression by immunohistochemistry (IHC). Statistical analyses were carried out to assess the prognostic value of Hsp27 expression for patients with this disease.</p> <p>Results</p> <p>Dysregulation of Hsp27 expression was observed in dysplastic lesions, primary OTSCC, and lymph node metastases, and appears to be associated with disease progression. Statistical analysis revealed that the reduced Hsp27 expression in primary tumor tissue was associated with poor differentiation. Furthermore, the higher expression of Hsp27 was correlated with better overall survival.</p> <p>Conclusion</p> <p>Our study confirmed that the dysregulation of Hsp27 expression is a frequent event during the progression of OTSCC. The expression of Hsp27 appears to be an independent prognostic marker for patients with this disease.</p

Effects of Water Inrush from Tunnel Excavation Face on the Deformation and Mechanical Performance of Shield Tunnel Segment Joints

Water inrush from the excavation face often occurs in the current shield construction of metro tunnels. In this study, the discontinuity of shield tunnel lining and the interaction between the tunnel segments, the grouting layer, and the surrounding rock are considered. Based on the 3D nonlinear contact theory, a hybrid model of the shield tunnel is constructed. Considering the fluid-solid coupling effect of water and soil, the influences of different water head differences on the mechanical performance and deformation of segments and joints in the shield tunnel are studied. The water gushing from the excavation face leads to vertical convergence of the cross-sectional area of the shield tunnel, and joint opening and dislocation result in sharp decrease of the waterproof capacity of joints. Meanwhile, the stress in the vicinity of segment joints increases sharply, and local cracks occur in the segment lining. The axial force, shear force, and bending moment in the joint bolt are also significantly increased. Based on the current metro standard and the computational results in this study, an emergency control criterion is put forward by means of controlling the discharge of water: the water head difference over the excavation face is required less than 4.6 M

Depth Image Denoising Algorithm Based on Fractional Calculus

Depth images are often accompanied by unavoidable and unpredictable noise. Depth image denoising algorithms mainly attempt to fill hole data and optimise edges. In this paper, we study in detail the problem of effectively filtering the data of depth images under noise interference. The classical filtering algorithm tends to blur edge and texture information, whereas the fractional integral operator can retain more edge and texture information. In this paper, the Grünwald–Letnikov-type fractional integral denoising operator is introduced into the depth image denoising process, and the convolution template of this operator is studied and improved upon to build a fractional integral denoising model and algorithm for depth image denoising. Depth images from the Redwood dataset were used to add noise, and the mask constructed by the fractional integral denoising operator was used to denoise the images by convolution. The experimental results show that the fractional integration order with the best denoising effect was −0.4 ≤ ν ≤ −0.3 and that the peak signal-to-noise ratio was improved by +3 to +6 dB. Under the same environment, median filter denoising had −15 to −30 dB distortion. The filtered depth image was converted to a point cloud image, from which the denoising effect was subjectively evaluated. Overall, the results prove that the fractional integral denoising operator can effectively handle noise in depth images while preserving their edge and texture information and thus has an excellent denoising effect

Sliding-Window TD-FrFT Algorithm for High-Precision Ranging of LFM Signals in the Presence of Impulse Noise

To address the performance degradation of the conventional linear frequency modulation signal ranging method in the presence of impulse noise, this paper proposes a novel technique that integrates a sliding-window tracking differentiator (TD) with the fractional Fourier transform (FrFT) ranging method. First, the sliding-window TD filtering algorithm is used to suppress the noise in the echo. Subsequently, the filtered signal is subjected to FrFT to calculate the time delay based on the difference in the peak point positions in the fractional domain for realizing target ranging. The simulation results show that the proposed method can effectively suppress impulse noise of different intensities and achieve an accurate and robust ranging of the target

The Mechanism of the Effect of Pre-Magnetized Butyl Xanthate on Chalcopyrite Flotation

In this work, we applied the technology of magnetic treatment to the flotation of chalcopyrite. The mechanism of the effect of pre-magnetized butyl xanthate on chalcopyrite flotation was studied using monomineral flotation tests, adsorption tests, conductivity tests, Fourier transform infrared spectroscopy (FTIR), etc. The monomineral flotation test results showed that, after the magnetization pretreatment of butyl xanthate solution, the chalcopyrite flotation recovery was increased by nearly two percentage points, and the dosage was reduced by 4&ndash;10 mg/L at the same recovery. The adsorption, FTIR, dissolved oxygen, and conductivity test results all showed that the magnetization pretreatment increased the dissolved oxygen content and promoted the oxidation of butyl xanthate to double xanthate with better selectivity to chalcopyrite. An electrochemical analysis showed that the magnetization pretreatment of butyl xanthate reduced the corrosion potential and corrosion current density of chalcopyrite surface and inhibited the self-corrosion process of chalcopyrite surface. The flotation test results of actual copper sulfide ore showed that pre-magnetized butyl xanthate could increase the copper recovery of copper concentrate by 3.06 percentage points and the sulfur recovery of sulfur concentrate by nearly 3 percentage points, and effectively reduce the mutual content of copper and sulfur concentrates

The Mechanism of the Effect of Pre-Magnetized Butyl Xanthate on Chalcopyrite Flotation

In this work, we applied the technology of magnetic treatment to the flotation of chalcopyrite. The mechanism of the effect of pre-magnetized butyl xanthate on chalcopyrite flotation was studied using monomineral flotation tests, adsorption tests, conductivity tests, Fourier transform infrared spectroscopy (FTIR), etc. The monomineral flotation test results showed that, after the magnetization pretreatment of butyl xanthate solution, the chalcopyrite flotation recovery was increased by nearly two percentage points, and the dosage was reduced by 4–10 mg/L at the same recovery. The adsorption, FTIR, dissolved oxygen, and conductivity test results all showed that the magnetization pretreatment increased the dissolved oxygen content and promoted the oxidation of butyl xanthate to double xanthate with better selectivity to chalcopyrite. An electrochemical analysis showed that the magnetization pretreatment of butyl xanthate reduced the corrosion potential and corrosion current density of chalcopyrite surface and inhibited the self-corrosion process of chalcopyrite surface. The flotation test results of actual copper sulfide ore showed that pre-magnetized butyl xanthate could increase the copper recovery of copper concentrate by 3.06 percentage points and the sulfur recovery of sulfur concentrate by nearly 3 percentage points, and effectively reduce the mutual content of copper and sulfur concentrates

Effects of Galvanic Interaction between Chalcopyrite and Monoclinic Pyrrhotite on Their Flotation Separation

The galvanic interaction between chalcopyrite and monoclinic pyrrhotite and its effect on flotation separation were studied using monomineral flotation tests, adsorption capacity tests, X-ray photoelectron spectroscopy (XPS) characterization, and scanning electron microscopy (SEM) test. These results showed that the interaction promoted the reduction of O2 on the cathodic chalcopyrite surface and accelerated the generation of Fe(OH)3, which was not conducive to collector adsorption; hence, the flotation recovery decreased by 10–16%. On the other hand, galvanic interaction accelerated the oxidation of S on the anodic monoclinic pyrrhotite surface to S0 or SO42− and produced a large amount of H+, thus preventing the formation of Fe(OH)3. Meanwhile, the Cu2+ eluted from chalcopyrite surface activated monoclinic pyrrhotite; hence, the flotation recovery increased by 3–10%. Galvanic interaction reduced the floatability difference between the two minerals, and the separation difficulty was significantly increased. Even with an increase in the amount of lime, the separation could not be improved