Multimodal Integration and Vividness in the Angular Gyrus During Episodic Encoding and Retrieval.

Much evidence suggests that the angular gyrus (AnG) is involved in episodic memory, but its precise role has yet to be determined. We examined two possible accounts within the same experimental paradigm: the "cortical binding of relational activity" (CoBRA) account (Shimamura, 2011), which suggests that the AnG acts as a convergence zone that binds multimodal episodic features, and the subjectivity account (Yazar et al., 2012), which implicates AnG involvement in subjective mnemonic experience (such as vividness or confidence). fMRI was used during both encoding and retrieval of paired associates. During study, female and male human participants memorized picture-pairs of common objects (in the unimodal task) or of an object-picture and an environmental sound (in the crossmodal task). At test, they performed a cued-recall task and further indicated the vividness of their memory. During retrieval, BOLD activation in the AnG was greatest for vividly remembered associates, consistent with the subjectivity account. During encoding, the same effect of vividness was found, but this was further modulated by task: greater activations were associated with subsequent recall in the crossmodal than the unimodal task. Therefore, encoding data suggest an additional role to the AnG in crossmodal integration, consistent with its role at retrieval proposed by CoBRA. These results resolve some of the puzzles in the literature and indicate that the AnG can play different roles during encoding and retrieval as determined by the cognitive demands posed by different mnemonic tasks.SIGNIFICANCE STATEMENT We offer new insights into the multiplicity of processes that are associated with angular gyrus (AnG) activation during encoding and retrieval of newly formed memories. We used fMRI while human participants learned and subsequently recalled pairs of objects presented to the same sensory modality or to different modalities. We were able to show that the AnG is involved when vivid memories are created and retrieved, as well as when encoded information is integrated across different sensory modalities. These findings provide novel evidence for the contribution of the AnG to our subjective experience of remembering alongside its role in integrative processes that promote subsequent memory

Effects of face repetition on ventral visual stream connectivity using dynamic causal modelling of fMRI data

Stimulus repetition normally causes reduced neural activity in brain regions that process that stimulus. Some theories claim that this “repetition suppression” reflects local mechanisms such as neuronal fatigue or sharpening within a region, whereas other theories claim that it results from changed connectivity between regions, following changes in synchrony or top-down predictions. In this study, we applied dynamic causal modeling (DCM) on a public fMRI dataset involving repeated presentations of faces and scrambled faces to test whether repetition affected local (self-connections) and/or between-region connectivity in left and right early visual cortex (EVC), occipital face area (OFA) and fusiform face area (FFA). Face “perception” (faces versus scrambled faces) modulated nearly all connections, within and between regions, including direct connections from EVC to FFA, supporting a non-hierarchical view of face processing. Face “recognition” (familiar versus unfamiliar faces) modulated connections between EVC and OFA/FFA, particularly in the left hemisphere. Most importantly, immediate and delayed repetition of stimuli were also best captured by modulations of connections between EVC and OFA/FFA, but not self-connections of OFA/FFA, consistent with synchronization or predictive coding theories, though also possibly reflecting local mechanisms like synaptic depression

Individual Radiation Protection Monitoring in the Marshall Islands: Utrok Atoll (2003-2004)

The United States Department of Energy (U.S. DOE) has recently implemented a series of strategic initiatives to address long-term radiological surveillance needs at former U.S. nuclear test sites in the Marshall Islands. The plan is to engage local atoll communities in developing shared responsibilities for implementing radiation protection monitoring programs for resettled and resettling populations in the northern Marshall Islands. Using the pooled resources of the U.S. DOE and local atoll governments, individual radiological surveillance programs have been developed in whole body counting and plutonium urinalysis in order to accurately assess radiation doses resulting from the ingestion and uptake of fallout radionuclides contained in locally grown foods. Permanent whole body counting facilities have been established at three separate locations in the Marshall Islands (Figure 1). These facilities are operated and maintained by Marshallese technicians with scientists from the Lawrence Livermore National Laboratory (LLNL) providing on-going technical support services. Bioassay samples are collected under controlled conditions and analyzed for plutonium isotopes at the Center for Accelerator Mass Spectrometry at LLNL using state-of-the art measurement technologies. We also conduct an on-going environmental monitoring and characterization program at selected sites in the northern Marshall Islands. The aim of the environmental program is to determine the level and distribution of important fallout radionuclides in soil, water and local foods with a view towards providing more accurate and updated dose assessments, incorporating knowledge of the unique behaviors and exposure pathways of fallout radionuclides in coral atoll ecosystems. These scientific studies have also been essential in helping guide the development of remedial options used in support of island resettlement. Together, the individual and environmental radiological surveillance programs are helping meet the informational needs of the U.S. DOE and the Republic of the Marshall Islands. Our updated environmental assessments provide a strong scientific basis for predicting future change in exposure conditions especially in relation to changes in life-style, diet and/or land-use patterns. This information has important implications in addressing questions about existing (and future) radiological conditions on the islands, in determining the cost and the effectiveness of potential remedial measures, and in general policy support considerations. Perhaps most importantly, the recently established individual radiological surveillance programs provide affected atoll communities with an unprecedented level of radiation protection monitoring where, for the first time, local resources are being made available to monitor resettled and resettling populations on a continuous basis. As a hard copy supplement to Marshall Islands Program website (http://eed.llnl.gov/mi/), this document provides an overview of the individual radiation surveillance monitoring program established for the Utrok Atoll population group along with a full disclosure of all verified measurement data (2003-2004). The Utrok whole body counting facility has been temporarily stationed on Majuro Atoll and, in cooperation with the Utrok Atoll Local Government, serves as a national facility open to the general public. Readers are advised that an additional feature of the associated website is a provision whereby users are able to calculate and track radiation doses delivered to volunteers (de-identified information only) participating in the Marshall Islands Radiological Surveillance Program

Personality traits and national dilemma Psychological perspectives of attitudes toward the peace process in the Middle East

SIGLEAvailable from British Library Document Supply Centre-DSC:DXN027415 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Integrating the SWAP and Rorschach composite measures for exploring psychopathological patterns of mental functioning

This study addressed the exploration of a multimethod psychodynamic assessment and its relation to psychopathological patterns. The study applies the Shedler-Westen Assessment Procedure (SWAP; Shedler, J., & Westen, D., 2006, Personality diagnosis with Shedler-Westen Assessment Procedure (SWAP): Bridging the gulf between science and practice. In P. D. M. Task Force (Ed.), Psychodynamic Diagnostic Manual (pp. 573–613). Silver Spring, MD: Alliance of Psychoanalytic Organizations.) and three composite Rorschach measures to a sample of 72 outpatients with various Diagnostic and Statistical Manual of Mental Disorders Axis I diagnoses (American Psychiatric Association, 2000, Diagnostic and Statistical Manual of Mental Disorders (DSM–IV–TR). Washington, DC: Author.): The Ego Impairment Index (EII-2; Viglione, D. J., Perry, W., & Meyer, G. J., 2003, Refinements in the Rorschach Ego Impairment Index incorporating the Human Representational Variable. Journal of Personality Assessment, 81, 149–156. doi:10.1207/S15327752JPA8102_06), measuring maladaptive ego functions; and two derivations of the Reality-Fantasy Scale (RFS; Tibon, S., Handelzalts, J. E., & Weinberger, Y., 2005. Using the Rorschach for exploring the concept of transitional space within the political context of the Middle East. International Journal of Applied Psychoanalytic Studies, 2, 40–57. doi:10.1002/aps.30): the RFS-P, measuring proneness to fantasy (lowered negative scores) as compared to concrete thinking (elevated positive scores); and the RFS-S, measuring dissociative proneness. Consistent with the literature, in this study, the multimethod assessment revealed modest unilinear associations, if any, between each of the Rorschach indices and the SWAP scales. However, regression analyses showed that the joint use of the EII-2 and the RFS-P explained a substantial portion of the variance in the SWAP scales that indicate inhibition and avoidance (obsessive personality disorder score and Avoidant Q factor, respectively). Furthermore, when used with the RFS-S, the EII-2 was able to significantly explain variance in the SWAP scales that indicate interpersonal detachment (schizotypal personality disorder score and Schizoid Q factor). The implications of these results for clinical practice will be discussed