2 research outputs found
Increasing Incidence of Hospitalization for Stroke and Transient Ischemic Attack in Young Adults:A Registry-Based Study
BACKGROUND: Studies have reported increasing incidence of ischemic stroke in adults younger than 50 to 55 years. Information on temporal trends of other stroke subtypes and transient ischemic attack (TIA) is sparse. The aim of this study was to investigate temporal trends of the incidence of hospitalizations for TIA and stroke including sexâ and subtypeâspecific trends in young adults aged 15 to 30Â years. METHODS AND RESULTS: From the Danish National Patient Register, we identified all cases of firstâever stroke and TIA (age 15â30Â years) in Denmark, who were hospitalized during the study period of 1994 to 2012. Incidence rates and estimated annual percentage changes (EAPCs) were estimated by using Poisson regression. During the study period, 4156 cases of firstâever hospitalization for stroke/TIA were identified. The ageâstandardized incidence rates of hospitalizations for stroke increased significantly (EAPC 1.83% [95% CI 1.11â2.55%]) from 11.97/100Â 000Â personâyears (PY) in 1994 to 16.77/100Â 000Â PY in 2012. TIA hospitalizations increased from 1.93/100Â 000Â PY in 1994 to 5.81/100Â 000Â PY in 2012 and after 2006 more markedly in men than in women (EAPC 16.61% [95% CI 10.45â23.12%]). The incidence of hospitalizations for ischemic stroke was markedly lower among men, but increased significantly from 2006 (EAPC 14.60% [95% CI 6.22â23.63%]). The incidences of hospitalizations for intracerebral hemorrhage and subarachnoid hemorrhage remained stable during the study period. CONCLUSIONS: The incidence rates of firstâtime hospitalizations for ischemic stroke and TIA in young Danish adults have increased substantially since the mid 1990s. The increase was particularly prominent in the most recent years