33 research outputs found
An Interactive Method Based on the Live Wire for Segmentation of the Breast in Mammography Images
A Survey on Service Route and Time Prediction in Instant Delivery: Taxonomy, Progress, and Prospects
Instant delivery services, such as food delivery and package delivery, have
achieved explosive growth in recent years by providing customers with
daily-life convenience. An emerging research area within these services is
service Route\&Time Prediction (RTP), which aims to estimate the future service
route as well as the arrival time of a given worker. As one of the most crucial
tasks in those service platforms, RTP stands central to enhancing user
satisfaction and trimming operational expenditures on these platforms. Despite
a plethora of algorithms developed to date, there is no systematic,
comprehensive survey to guide researchers in this domain. To fill this gap, our
work presents the first comprehensive survey that methodically categorizes
recent advances in service route and time prediction. We start by defining the
RTP challenge and then delve into the metrics that are often employed.
Following that, we scrutinize the existing RTP methodologies, presenting a
novel taxonomy of them. We categorize these methods based on three criteria:
(i) type of task, subdivided into only-route prediction, only-time prediction,
and joint route\&time prediction; (ii) model architecture, which encompasses
sequence-based and graph-based models; and (iii) learning paradigm, including
Supervised Learning (SL) and Deep Reinforcement Learning (DRL). Conclusively,
we highlight the limitations of current research and suggest prospective
avenues. We believe that the taxonomy, progress, and prospects introduced in
this paper can significantly promote the development of this field
Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021.MethodsWe estimated mortality, prevalence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs), with corresponding 95% uncertainty intervals (UIs), by age and sex in 204 countries and territories, from 1990 to 2021. We included morbidity and deaths due to neurological conditions, for which health loss is directly due to damage to the CNS or peripheral nervous system. We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, preterm birth, and sepsis), infectious diseases (ie, COVID-19, cystic echinococcosis, malaria, syphilis, and Zika virus disease), and diabetic neuropathy. By conducting a sequela-level analysis of the health outcomes for these conditions, only cases where nervous system damage occurred were included, and YLDs were recalculated to isolate the non-fatal burden directly attributable to nervous system health loss. A comorbidity correction was used to calculate total prevalence of all conditions that affect the nervous system combined.FindingsGlobally, the 37 conditions affecting the nervous system were collectively ranked as the leading group cause of DALYs in 2021 (443 million, 95% UI 378–521), affecting 3·40 billion (3·20–3·62) individuals (43·1%, 40·5–45·9 of the global population); global DALY counts attributed to these conditions increased by 18·2% (8·7–26·7) between 1990 and 2021. Age-standardised rates of deaths per 100 000 people attributed to these conditions decreased from 1990 to 2021 by 33·6% (27·6–38·8), and age-standardised rates of DALYs attributed to these conditions decreased by 27·0% (21·5–32·4). Age-standardised prevalence was almost stable, with a change of 1·5% (0·7–2·4). The ten conditions with the highest age-standardised DALYs in 2021 were stroke, neonatal encephalopathy, migraine, Alzheimer's disease and other dementias, diabetic neuropathy, meningitis, epilepsy, neurological complications due to preterm birth, autism spectrum disorder, and nervous system cancer.InterpretationAs the leading cause of overall disease burden in the world, with increasing global DALY counts, effective prevention, treatment, and rehabilitation strategies for disorders affecting the nervous system are needed
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Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
BACKGROUND Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations. METHODS The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational locations for each year from 1990 until 2021. The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model-a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates-with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. YLLs were computed as the product of the number of deaths for each cause-age-sex-location-year and the standard life expectancy at each age. As part of the modelling process, uncertainty intervals (UIs) were generated using the 2·5th and 97·5th percentiles from a 1000-draw distribution for each metric. We decomposed life expectancy by cause of death, location, and year to show cause-specific effects on life expectancy from 1990 to 2021. We also used the coefficient of variation and the fraction of population affected by 90% of deaths to highlight concentrations of mortality. Findings are reported in counts and age-standardised rates. Methodological improvements for cause-of-death estimates in GBD 2021 include the expansion of under-5-years age group to include four new age groups, enhanced methods to account for stochastic variation of sparse data, and the inclusion of COVID-19 and other pandemic-related mortality-which includes excess mortality associated with the pandemic, excluding COVID-19, lower respiratory infections, measles, malaria, and pertussis. For this analysis, 199 new country-years of vital registration cause-of-death data, 5 country-years of surveillance data, 21 country-years of verbal autopsy data, and 94 country-years of other data types were added to those used in previous GBD rounds. FINDINGS The leading causes of age-standardised deaths globally were the same in 2019 as they were in 1990; in descending order, these were, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections. In 2021, however, COVID-19 replaced stroke as the second-leading age-standardised cause of death, with 94·0 deaths (95% UI 89·2-100·0) per 100 000 population. The COVID-19 pandemic shifted the rankings of the leading five causes, lowering stroke to the third-leading and chronic obstructive pulmonary disease to the fourth-leading position. In 2021, the highest age-standardised death rates from COVID-19 occurred in sub-Saharan Africa (271·0 deaths [250·1-290·7] per 100 000 population) and Latin America and the Caribbean (195·4 deaths [182·1-211·4] per 100 000 population). The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4-48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3-37·2] per 100 000 population). Globally, life expectancy steadily improved between 1990 and 2019 for 18 of the 22 investigated causes. Decomposition of global and regional life expectancy showed the positive effect that reductions in deaths from enteric infections, lower respiratory infections, stroke, and neonatal deaths, among others have contributed to improved survival over the study period. However, a net reduction of 1·6 years occurred in global life expectancy between 2019 and 2021, primarily due to increased death rates from COVID-19 and other pandemic-related mortality. Life expectancy was highly variable between super-regions over the study period, with southeast Asia, east Asia, and Oceania gaining 8·3 years (6·7-9·9) overall, while having the smallest reduction in life expectancy due to COVID-19 (0·4 years). The largest reduction in life expectancy due to COVID-19 occurred in Latin America and the Caribbean (3·6 years). Additionally, 53 of the 288 causes of death were highly concentrated in locations with less than 50% of the global population as of 2021, and these causes of death became progressively more concentrated since 1990, when only 44 causes showed this pattern. The concentration phenomenon is discussed heuristically with respect to enteric and lower respiratory infections, malaria, HIV/AIDS, neonatal disorders, tuberculosis, and measles. INTERPRETATION Long-standing gains in life expectancy and reductions in many of the leading causes of death have been disrupted by the COVID-19 pandemic, the adverse effects of which were spread unevenly among populations. Despite the pandemic, there has been continued progress in combatting several notable causes of death, leading to improved global life expectancy over the study period. Each of the seven GBD super-regions showed an overall improvement from 1990 and 2021, obscuring the negative effect in the years of the pandemic. Additionally, our findings regarding regional variation in causes of death driving increases in life expectancy hold clear policy utility. Analyses of shifting mortality trends reveal that several causes, once widespread globally, are now increasingly concentrated geographically. These changes in mortality concentration, alongside further investigation of changing risks, interventions, and relevant policy, present an important opportunity to deepen our understanding of mortality-reduction strategies. Examining patterns in mortality concentration might reveal areas where successful public health interventions have been implemented. Translating these successes to locations where certain causes of death remain entrenched can inform policies that work to improve life expectancy for people everywhere. FUNDING Bill & Melinda Gates Foundation
A Comprehensive Review of Stratification and Rollover Behavior of Liquefied Natural Gas in Storage Tanks
Liquefied natural gas (LNG), as cleaner transitional energy than coal, is becoming increasingly prominent in the energy structure of various countries based on their low-carbon background, and its demand has grown rapidly worldwide. Storage tanks are the most commonly used LNG storage facilities. Owing to a variety of internal composition and external environmental factors, the instability phenomenon of LNG in the tanks may occur during storage, leading to potential safety risks. An in-depth understanding of the stratification and rollover behavior of LNG is therefore required to ensure and promote efficient utilization and stable storage of LNG. This paper provides a comprehensive review of the current state of LNG stratification and rollover behavior. The factors for causing LNG stratification and rollover behavior in the storage tanks are summarized, methods for characterizing stratification and rollover behavior are discussed, and measures for inhibiting the instability phenomenon of LNG in the tanks are highlighted. Future researchers should conduct further work in enriching the factors affecting the stratification and rollover behavior, improving characterization methods, and developing inhibition measures to ensure the safe and stable storage of LNG
Synthesis and mechanism study of temperature- and salt-resistant amphoteric polyacrylamide with MAPTAC and DTAB as monomers
The failure of thickeners at high temperature results in gelled acid acidification fracturing. To solve the problem, 8 kinds of polymers were synthesized by free radical polymerization of aqueous solution using AM, AMPS, NaAMPS, MAPTAC, DTAB and NVP as raw materials. The polymer was characterized by infrared spectroscopy and viscosity-average molecular weight, and the temperature resistance, rheology, salt resistance and shear resistance of the polymer solution were compared, and the mechanism was analyzed. The results show that the viscosity of GTY−2 is 181.52 mPa·s, and the viscosity loss rate is 56.89% at 180 °C and 100 s−1, and its temperature resistance is the best. Meanwhile, the viscosity retention rate of GTY−2 is 84.58% after 160 min shear, showing the strongest shear resistance. The viscosity loss rate of GTY−1 in 20% hydrochloric acid solution is 80.88%, and its acid resistance is stronger than that of GTY−2. Moreover, due to the amphiphilicity of DTAB, the molecular hydration film becomes thicker, and the salt resistance of GTY−2 is lower than that of GTY−1. The experimental results show that GTY−1 and GTY−2 have good temperature resistance, salt resistance, acid resistance and shear resistance, and can be used as thickeners for acid fracturing with thickened acid to improve the effect of acid fracturing under high temperature conditions.Published versionThe authors are grateful for the National Natural Science Foundation of China (No. 51574089)
Synthesis and Mechanism Study of Temperature- and Salt-Resistant Amphoteric Polyacrylamide with MAPTAC and DTAB as Monomers
The failure of thickeners at high temperature results in gelled acid acidification fracturing. To solve the problem, 8 kinds of polymers were synthesized by free radical polymerization of aqueous solution using AM, AMPS, NaAMPS, MAPTAC, DTAB and NVP as raw materials. The polymer was characterized by infrared spectroscopy and viscosity-average molecular weight, and the temperature resistance, rheology, salt resistance and shear resistance of the polymer solution were compared, and the mechanism was analyzed. The results show that the viscosity of GTY−2 is 181.52 mPa·s, and the viscosity loss rate is 56.89% at 180 °C and 100 s−1, and its temperature resistance is the best. Meanwhile, the viscosity retention rate of GTY−2 is 84.58% after 160 min shear, showing the strongest shear resistance. The viscosity loss rate of GTY−1 in 20% hydrochloric acid solution is 80.88%, and its acid resistance is stronger than that of GTY−2. Moreover, due to the amphiphilicity of DTAB, the molecular hydration film becomes thicker, and the salt resistance of GTY−2 is lower than that of GTY−1. The experimental results show that GTY−1 and GTY−2 have good temperature resistance, salt resistance, acid resistance and shear resistance, and can be used as thickeners for acid fracturing with thickened acid to improve the effect of acid fracturing under high temperature conditions
A systematic review and meta-analysis of balance training in patients with chronic ankle instability
Abstract Background Chronic ankle instability (CAI) is a common yet serious problem for elder patients. This meta-analysis aimed to evaluate the effects of balance training for CAI, to provide evidence for the clinical treatment, and care of CAI patients. Methods Two investigators searched PubMed, EMBASE, Science Direct, Web of Science, Cochrane Library, China National Knowledge Infrastructure, Wanfang, and Weipu Databases up to May 20, 2023, for randomized controlled trials (RCTs) on the effects of balance training for CAI. The mean difference (MD) with 95% confidence intervals (95%CIs) was calculated for each outcome with a fixed or random effect model. Review Manager 5.3 software was used for meta-analysis. Results Nine RCTs involving 341 patients were included. Meta-analysis results showed that compared with blank controls, balanced training treatment of CAI could significantly improve the score of CAI [MD = 3.95, 95% CI (3.26, 4.64), P < 0.00001], SEBT-PM [MD = 4.94, 95% CI (1.88, 8.00), P = 0.002], SEBT-PL [MD = 5.19, 95% CI (1.57, 8.81), P = 0.005], and FAAM Sports [MD = 17.74, 95% CI (14.36, 21.11), P < 0.00001]. Compared with strength training, balance training treatment of CAI improved the score of CAIT [MD = 2.36, 95% CI (0.29, 4.44), P = 0.03], FAAM-ADL [MD = 4.06, 95% CI (1.30, 6.83), P = 0.004]. Conclusion The analysis outcomes indicate that balance training enhances daily activity capability, motor function, and dynamic balance to different extents. Additionally, when comparing the results of balance training and strength training, no significant difference was observed between the two methods in improving the dynamic stability of CAI patients. However, it is noteworthy that balance training exhibits a more pronounced impact on enhancing functional scale scores
Arsenic Transformation in Swine Wastewater with Low-Arsenic Content during Anaerobic Digestion
In this study, the raw wastewater (RW), and effluents from the acidogenic phase (AP) and methanogenic phase (MP) in a swine wastewater treatment plant were collected to investigate the occurrence and transformation of arsenic (As), as well as the abundance of As metabolism genes during the anaerobic digestion (AD) process. The results showed that total concentrations of As generally decreased by 33–71% after AD. Further analysis showed that the As species of the dissolved fractions were present mainly as dimethylarsinic acid (DMA), with arsenite (As(III)) and arsenate (As(V)) as the minor species. Moreover, real-time PCR (qPCR) results showed that As metabolism genes (arsC, arsenate reduction gene; aioA, arsenite oxidation gene and arsM, arsenite methylation gene) were highly abundant, with arsM being predominant among the metabolism genes. This study provides reliable evidence on As biotransformation in swine wastewater treatment process, suggesting that AD could be a valuable treatment to mitigate the risk of As in wastewater
Social Media-Based Health Management Systems and Sustained Health Engagement: TPB Perspective
Background: With the popularity of mobile Internet and social networks, an increasing number of social media-based health management systems (SocialHMS) have emerged in recent years. These social media-based systems have been widely used in registration, payment, decision-making, chronic diseases management, health information and medical expenses inquiry, etc., and they greatly facilitate the convenience for people to obtain health services. Objective: This study aimed to investigate the factors influencing sustained health engagement of SocialHMS by combining the theory of planned behavior (TPB) with the big-five theory and the trust theory. Method: We completed an empirical analysis based on the 494 pieces of data collected from Anhui Medical University first affiliated hospital (AMU) in East China through structural equation modeling and SmartPLS (statistical analysis software). Results: Openness to new experience has a significantly positive influence on attitude (path coefficient = 0.671, t = 24.0571, R2 = 0.451), perceived behavioral control (path coefficient = 0.752, t = 32.2893, R2 = 0.565), and perceived risk (path coefficient = 0.651, t = 18.5940, R2 = 0.424), respectively. Attitude, perceived behavioral control, subjective norms, and trust have a significantly positive influence on sustained health engagement (path coefficients = 0.206, 0.305, 0.197, 0.183 respectively, t = 3.6684, 4.9158, 4.3414, and 3.3715, respectively). The explained variance of the above factors to the sustained health engagement of SocialHMS is 60.7% (R2 = 0.607). Perceived risk has a significantly negative influence on trust (path coefficient = 0.825, t = 46.9598, R2 = 0.681). Conclusions: Attitude, perceived behavioral control, subjective norm, and trust are the determinants that affect sustained health engagement. The users’ personality trait of openness to new experience and perceived risk were also found to be important factors for sustained health engagement. For hospital managers, there is the possibility to take appropriate measures based on users’ personality to further enhance the implementation and utilization of SocialHMS. As for system suppliers, they can provide the optimal design for SocialHMS so as to meet users’ needs