23,650 research outputs found

    Adiabatic State Conversion and Pulse Transmission in Optomechanical Systems

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    Optomechanical systems with strong coupling can be a powerful medium for quantum state engineering. Here, we show that quantum state conversion between cavity modes with different wavelengths can be realized with high fidelity by adiabatically varying the effective optomechanical couplings. The fidelity for the conversion of gaussian states is derived by solving the Langevin equation in the adiabatic limit. We also show that photon pulses can be transmitted between input-output channels with different wavelengths via the effective optomechanical couplings and the output pulse shape can also be manipulated.Comment: 5 pages, 2 figures. Supplementary Materials at http://prl.aps.org/supplemental/PRL/v108/i15/e15360

    Clinical Features and Genetic Analysis of 20 Chinese Patients with X-Linked Hyper-IgM Syndrome

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    X-linked hyper-IgM syndrome (XHIGM) is one type of primary immunodeficiency diseases, resulting from defects in the CD40 ligand/CD40 signaling pathways. We retrospectively analyzed the clinical and molecular features of 20 Chinese patients diagnosed and followed up in hospitals affiliated to Shanghai Jiao Tong University School of Medicine from 1999 to 2013. The median onset age of these patients was 8.5 months (range: 20 days–21 months). Half of them had positive family histories, with a shorter diagnosis lag. The most common symptoms were recurrent sinopulmonary infections (18 patients, 90%), neutropenia (14 patients, 70%), oral ulcer (13 patients, 65%), and protracted diarrhea (13 patients, 65%). Six patients had BCGitis. Six patients received hematopoietic stem cell transplantations and four of them had immune reconstructions and clinical remissions. Eighteen unique mutations in CD40L gene were identified in these 20 patients from 19 unrelated families, with 12 novel mutations. We compared with reported mutation results and used bioinformatics software to predict the effects of mutations on the target protein. These mutations reflected the heterogeneity of CD40L gene and expanded our understanding of XHIGM

    Self organized criticality in an improved Olami-Feder-Christensen model

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    An improved version of the Olami-Feder-Christensen model has been introduced to consider avalanche size differences. Our model well demonstrates the power-law behavior and finite size scaling of avalanche size distribution in any range of the adding parameter paddp_{add} of the model. The probability density functions (PDFs) for the avalanche size differences at consecutive time steps (defined as returns) appear to be well approached, in the thermodynamic limit, by q-Gaussian shape with appropriate q values which can be obtained a priori from the avalanche size exponent Ï„\tau. For the small system sizes, however, return distributions are found to be consistent with the crossover formulas proposed recently in Tsallis and Tirnakli, J. Phys.: Conf. Ser. 201, 012001 (2010). Our results strengthen recent findings of Caruso et al. [Phys. Rev. E 75, 055101(R) (2007)] on the real earthquake data which support the hypothesis that knowing the magnitude of previous earthquakes does not make the magnitude of the next earthquake predictable. Moreover, the scaling relation of the waiting time distribution of the model has also been found.Comment: 16 pages, 6 figure
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