23,650 research outputs found
Adiabatic State Conversion and Pulse Transmission in Optomechanical Systems
Optomechanical systems with strong coupling can be a powerful medium for
quantum state engineering. Here, we show that quantum state conversion between
cavity modes with different wavelengths can be realized with high fidelity by
adiabatically varying the effective optomechanical couplings. The fidelity for
the conversion of gaussian states is derived by solving the Langevin equation
in the adiabatic limit. We also show that photon pulses can be transmitted
between input-output channels with different wavelengths via the effective
optomechanical couplings and the output pulse shape can also be manipulated.Comment: 5 pages, 2 figures. Supplementary Materials at
http://prl.aps.org/supplemental/PRL/v108/i15/e15360
Clinical Features and Genetic Analysis of 20 Chinese Patients with X-Linked Hyper-IgM Syndrome
X-linked hyper-IgM syndrome (XHIGM) is one type of primary immunodeficiency diseases, resulting from defects in the CD40 ligand/CD40 signaling pathways. We retrospectively analyzed the clinical and molecular features of 20 Chinese patients diagnosed and followed up in hospitals affiliated to Shanghai Jiao Tong University School of Medicine from 1999 to 2013. The median onset age of these patients was 8.5 months (range: 20 days–21 months). Half of them had positive family histories, with a shorter diagnosis lag. The most common symptoms were recurrent sinopulmonary infections (18 patients, 90%), neutropenia (14 patients, 70%), oral ulcer (13 patients, 65%), and protracted diarrhea (13 patients, 65%). Six patients had BCGitis. Six patients received hematopoietic stem cell transplantations and four of them had immune reconstructions and clinical remissions. Eighteen unique mutations in CD40L gene were identified in these 20 patients from 19 unrelated families, with 12 novel mutations. We compared with reported mutation results and used bioinformatics software to predict the effects of mutations on the target protein. These mutations reflected the heterogeneity of CD40L gene and expanded our understanding of XHIGM
Self organized criticality in an improved Olami-Feder-Christensen model
An improved version of the Olami-Feder-Christensen model has been introduced
to consider avalanche size differences. Our model well demonstrates the
power-law behavior and finite size scaling of avalanche size distribution in
any range of the adding parameter of the model. The probability
density functions (PDFs) for the avalanche size differences at consecutive time
steps (defined as returns) appear to be well approached, in the thermodynamic
limit, by q-Gaussian shape with appropriate q values which can be obtained a
priori from the avalanche size exponent . For the small system sizes,
however, return distributions are found to be consistent with the crossover
formulas proposed recently in Tsallis and Tirnakli, J. Phys.: Conf. Ser. 201,
012001 (2010). Our results strengthen recent findings of Caruso et al. [Phys.
Rev. E 75, 055101(R) (2007)] on the real earthquake data which support the
hypothesis that knowing the magnitude of previous earthquakes does not make the
magnitude of the next earthquake predictable. Moreover, the scaling relation of
the waiting time distribution of the model has also been found.Comment: 16 pages, 6 figure
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