A new model for the double well potential

A new model for the double well potential is presented in the paper. In the new potential, the exchanging rate could be easily calculated by the perturbation method in supersymmetric quantum mechanics. It gives good results whether the barrier is high or sallow. The new model have many merits and may be used in the double well problem.Comment: 3pages, 3figure

4,4′-Dimethyl-2,2′-[1,2-phenyl­enebis(nitrilo­methyl­idyne)]diphenol

In the title Schiff base, C22H20N2O2, the benzene ring forms dihedral angles of 53.92 (1) and 3.62 (1)° with the two salicylaldimine groups. There are two strong O—H⋯N intra­molecular hydrogen bonds. The crystal packing is stabilized by weak inter­molecular C—H⋯O hydrogen bonds and π–π stacking inter­actions (average distance 3.39 Å)

Creating hospital-specific customized clinical pathways by applying semantic reasoning to clinical data

AbstractObjectiveClinical pathways (CPs) are widely studied methods to standardize clinical intervention and improve medical quality. However, standard care plans defined in current CPs are too general to execute in a practical healthcare environment. The purpose of this study was to create hospital-specific personalized CPs by explicitly expressing and replenishing the general knowledge of CPs by applying semantic analysis and reasoning to historical clinical data.MethodsA semantic data model was constructed to semantically store clinical data. After querying semantic clinical data, treatment procedures were extracted. Four properties were self-defined for local ontology construction and semantic transformation, and three Jena rules were proposed to achieve error correction and pathway order recognition. Semantic reasoning was utilized to establish the relationship between data orders and pathway orders.ResultsA clinical pathway for deviated nasal septum was used as an example to illustrate how to combine standard care plans and practical treatment procedures. A group of 224 patients with 11,473 orders was transformed to a semantic data model, which was stored in RDF format. Long term order processing and error correction made the treatment procedures more consistent with clinical practice. The percentage of each pathway order with different probabilities was calculated to declare the commonality between the standard care plans and practical treatment procedures. Detailed treatment procedures with pathway orders, deduced pathway orders, and orders with probability greater than 80% were provided to efficiently customize the CPs.ConclusionsThis study contributes to the practical application of pathway specifications recommended by the Ministry of Health of China and provides a generic framework for the hospital-specific customization of standard care plans defined by CPs or clinical guidelines

Identification of alternative splicing variants of the β subunit of human Ca2+/calmodulin-dependent protein kinase II with different activities

AbstractThe β subunit of human Ca2+/calmodulin-dependent protein kinase II (β CaMKII) was identified by searching through an expressed sequence tag database and rapid amplification of cDNA 5′-ends and was assigned to chromosome 7. Reverse transcription-polymerase chain reaction and sequencing analysis identified at least five alternative splicing variants of β CaMKII (β, β6, βe, β′e, and β7) in brain and two of them (β6 and β7) were first detected in any species. When expressed in HEK 293 cells, the Ca2+/calmodulin-dependent kinase activity of β7, the shortest variant, was much lower than that of either β (the longest one) or βe (the medium one), suggesting possible regulation of β CaMKII activity by alternative splicing

Non-Abelian dynamical gauge field and topological superfluids in optical Raman lattice

We propose an experimental scheme to realize non-Abelian dynamical gauge field for ultracold fermions, which induces a novel pairing mechanism of topological superfluidity. The dynamical gauge fields arise from nontrivial interplay effect between the strong Zeeman splitting and Hubbard interaction in a two-dimensional (2D) optical Raman lattice. The spin-flip transitions are forbidden by the large Zeeman detuning, but are restored when the Zeeman splitting is compensated by Hubbard interaction. This scheme allows to generate a dynamical non-Abelian gauge field that leads to a Dirac type correlated 2D spin-orbit interaction depending on local state configurations. The topological superfluid from a novel pairing driven by 2D dynamical gauge fields is reached, with analytic and numerical results being obtained. Our work may open up a door to emulate non-Abelian dynamical gauge fields and correlated topological phases with experimental feasibility.Comment: 5+7 pages, 4+6 figure

Magnetic Borophenes from an Evolutionary Search

A computational methodology based on ab initio evolutionary algorithms and spin-polarized density functional theory was developed to predict two-dimensional magnetic materials. Its application to a model system borophene reveals an unexpected rich magnetism and polymorphism. A metastable borophene with nonzero thickness is an antiferromagnetic semiconductor from first-principles calculations, and can be further tuned into a half-metal by finite electron doping. In this borophene, the buckling and coupling among three atomic layers are not only responsible for magnetism, but also result in an out-of-plane negative Poisson\u27s ratio under uniaxial tension, making it the first elemental material possessing auxetic and magnetic properties simultaneously