898 research outputs found
3,8-Dimethyl-4-oxo-3,4-dihydroÂquinazoline-6-carbonitrile
In the title compound, C11H9N3O, the quinazoline unit is almost planar, with a mean deviation of 0.006 (1) Å from the least-squares plane defined by the ten constituent atoms. In the crystal, molÂecules are linked by weak C—H⋯N hydrogen bonds
Clinical observation on the reconstruction of large areas lower eyelid defect with Medpor spacer graft
AIM: To observe the effects of porous polyethylene(Medpor)as a spacer graft in the reconstruction of large areas eyelid defect after the operation of malignant tumors of lower eyelids.<p>METHODS: Nineteen cases(19 eyes)of malignant tumors of lower eyelid underwent the eyelid reconstruction were selected. Medpor lower eyelid inserts implantation were used to replace tarsal joint sliding conjunctival flap and pedicle flap, and repaired full-thickness lower eyelid defects then underwent eyelid reconstruction. <p>RESULTS: Appearance of eyelids and functional improvements were satisfactory with no stimulation on the eyeball and no effect on the visual function. Implants is with no absorption, shift, exclusion or infection and no tumor recurrence in all cases during the follow up for 6-36mo.<p>CONCLUSION: Medpor lower eyelid inserts implantation can instead tarsal plate for the reconstruction of medium to large areas lower eyelid defect, which is easy performing with rare complications. It is an ideal alternatives of tarsal plate
Brusatol
The title compound, C26H32O11, is composed of an α,β-unsaturated cycloÂhexaÂnone ring (A), two cycloÂhexane rings (B and C), a six-membered lactone ring (D) and tetraÂhydroÂfuran ring (E). Ring A exists in a half-chair conformation with a C atom displaced by 0.679 (2) Å from the mean plane through the remaining five atoms. Ring B exists in a normal chair conformation. Both rings C and D exist in a twisted-chair conformation due to the O-atom bridge and the carbonyl group in rings C and D, respectively. Ring E shows an envelope conformation with a C atom displaced by 0.761 (1) Å from the mean plane through the remaining five atoms. The ring junctions are A/B trans, B/C trans, C/D cis and D/E cis. An intraÂmolecular O—H⋯O hydrogen bond occurs. In the crystal, O—H⋯O hydrogen bonds involving the hyÂdroxy, lactone and ester groups and C—H⋯O interÂactions are observed
catena-Poly[[(2,2′-bipyridine)Âmanganese(II)]-μ3-4,4′-sulfonylÂdibenzoato]
In the title compound, [Mn(C14H8O6S)(C10H8N2)]n, the MnII ion is coordinated by four O atoms from three 4,4′-sulfonylÂdibenzoate (sdba) ligands and two N atoms from one 2,2′-bipyridine (2,2′-bipy) ligand in a distorted octaÂhedral geometry. The manganese atoms are alternately bridged either by two sdba ligands, with an Mn⋯Mn separation of 12.284 (1) Å, or by two carboxylÂate groups from two sdba ligands, with an Mn⋯Mn separation of 4.064 (1) Å, thus producing polymeric chains propagated in [101]. Weak interÂmolecular C—H⋯O hydrogen bonds and π–π interÂactions [centroid–centroid distance of 3.730 (3) Å between the aromatic rings of neighbouring polymeric chains] further stabilize the crystal packing
Secohellebrigeninamide
The title compound, C26H37NO5, was the reaction product of hellebrigenin with N,N-dimethylÂformamide. It consists of three cycloÂhexane rings (A, B and C), one five-membered ring (D) and one dihydroÂpyran ring (E). The stereochemistry of the ring junctions is is A/B cis, B/C trans, C/D cis and C/E trans. The cycloÂhexane rings A, B and C have chair conformations. Both the five-membered ring D and the dihydroÂpyran ring adopt an envelope conformation. Two orientations are found for the aldehyde group with occupancies of 0.608 (10) and 0.392 (10). In the crystal, short O—H⋯O hydrogen bonds and short C—H⋯O contacts involving the hyÂdroxy group, terminal methyl group and carbonyl group link the molÂecules into a three-dimensional network
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