Pinning Cluster Synchronization in Linear Hybrid Coupled Delayed Dynamical Networks

The problem on cluster synchronization will be investigated for a class of delayed dynamical networks based on pinning control strategy. Through utilizing the combined convex technique and Kronecker product, two sufficient conditions can be derived to ensure the desired synchronization when the designed feedback controller is employed to each cluster. Moreover, the inner coupling matrices are unnecessarily restricted to be diagonal and the controller design can be converted into solving a series of linear matrix inequalities (LMIs), which greatly improve the present methods. Finally, two numerical examples are provided to demonstrate the effectiveness and reduced conservatism

A method for protein extraction from different subcellular fractions of laticifer latex in Hevea brasiliensis compatible with 2-DE and MS

<p>Abstract</p> <p>Background</p> <p>Proteomic analysis of laticifer latex in <it>Hevea brasiliensis </it>has been received more significant attentions. However, the sticky and viscous characteristic of rubber latex as cytoplasm of laticifer cells and the complication of laticifer latex membrane systems has made it challenge to isolate high-quality proteins for 2-DE and MS.</p> <p>Results</p> <p>Based on the reported Borax/PVPP/Phenol (BPP) protocol, we developed an efficient method for protein preparation from different latex subcellular fractions and constructed high-resolution reference 2-DE maps. The obtained proteins from both total latex and C-serum fraction with this protocol generate more than one thousand protein spots and several hundreds of protein spots from rubber particles as well as lutoid fraction and its membranes on the CBB stained 2-DE gels. The identification of 13 representative proteins on 2-DE gels by MALDI TOF/TOF MS/MS suggested that this method is compatible with MS.</p> <p>Conclusion</p> <p>The proteins extracted by this method are compatible with 2-DE and MS. This protein preparation protocol is expected to be used in future comparative proteomic analysis for natural rubber latex.</p

Robotic versus laparoscopic right hemicolectomy with complete mesocolic excision: a retrospective multicenter study with propensity score matching

ObjectiveDuring the past decade, the concept of complete mesocolic excision (CME) has been developed in an attempt to minimize recurrence for right-sided colon cancer. This study aims to compare outcomes of robotic versus laparoscopic right hemicolectomy with CME for right-sided colon cancer.MethodsWe performed a retrospective multicenter propensity score matching study. From July 2016 to July 2021, 382 consecutive patients from different Chinese surgical departments were available for inclusion out of an initial cohort of 412, who underwent robotic or laparoscopic right hemicolectomy with CME. Data of all patients were retrospectively collected and reviewed. Of these, 149 cases were performed by a robotic approach, while the other 233 cases were done by laparoscopy. Propensity score matching was applied at a ratio of 1:1 to compare perioperative, pathologic, and oncologic outcomes between the robotic and the laparoscopic groups (n = 142).ResultsBefore propensity score matching, there were no statistical differences regarding the sex, history of abdominal surgery, body mass index (BMI), American Joint Committee on Cancer (AJCC) staging system, tumor location, and center between groups (p &gt; 0.05), while a significant difference was observed regarding age (p = 0.029). After matching, two comparable groups of 142 cases were obtained with equivalent patient characteristics (p &gt; 0.05). Blood loss, time to oral intake, return of bowel function, length of stay, and complications were not different between groups (p &gt; 0.05). The robotic group showed a significantly lower conversion rate (0% vs. 4.2%, p = 0.03), but a longer operative time (200.9 min vs. 182.3 min, p &lt; 0.001) and a higher total hospital cost (85,016 RMB vs. 58,266 RMB, p &lt; 0.001) compared with the laparoscopic group. The number of harvested lymph nodes was comparable (20.4 vs. 20.5, p = 0.861). Incidence of complications, mortality, and pathologic outcomes were similar between groups (p &gt; 0.05). The 2-year disease-free survival rates were 84.9% and 87.1% (p = 0.679), and the overall survival rates between groups were 83.8% and 80.7% (p = 0.943).ConclusionDespite the limitations of a retrospective analysis, the outcomes of robotic right hemicolectomy with CME were comparable to the laparoscopic procedures with fewer conversions to open surgery. More clinical advantages of the robotic surgery system need to be further confirmed by well-conducted randomized clinical trials with large cohorts of patients

The Existence of Positive Solution to Three-Point Singular Boundary Value Problem of Fractional Differential Equation

We investigate the existence of positive solution to nonlinear fractional differential equation three-point singular boundary value problem: Dqu(t)+f(t,u(t))=0, 0<t<1, u(0)=0, u(1)=αD(q−1)/2u(t)|t=ξ, where 1<q≤2 is a real number, ξ∈(0,1/2], α∈(0,+∞) and αΓ(q)ξ(q−1)/2<Γ((q+1)/2),Dq is the standard Riemann-Liouville fractional derivative, and f∈C((0,1]×[0,+∞),[0,+∞)),lim⁡t→+0f(t,⋅)=+∞ (i.e., f is singular at t=0). By using the fixed-point index theory, the existence result of positive solutions is obtained

Synthesis and Evaluation of Bio-Based Plasticizers from 5-Hydroxymethyl-2-Furancarboxylic Acid for Poly(vinyl chloride)

5-Hydroxymethyl-2-furancarboxylic acid (HFCA), a promising biomonomer from renewable resources, was used to synthesize two bio-based plasticizers, namely, hexyl 5-((hexanoyloxy)methyl)-2-furancarboxylate (HHMFC) and dihexyl 5,5'-(oxybis(methylene))bis(furan-2-carboxylate) (DHOBFC). The chemical structures of these prepared plasticizers were confirmed using Fourier transform infrared and nuclear magnetic resonance, and then, their plasticization effects on poly(vinyl chloride) (PVC) were also studied. As a result, HFCA-based plasticizers were miscible with PVC and exhibited excellent plasticization performances, compared with commercial dioctyl phthalate. It was noted that HHMFC had a much better plasticizing effect on the PVC film than DHOBFC; however, it displayed a poorer volatility resistance and exudation resistance, which could be attributed to its smaller molecular weight. Besides, because each rigid furan ring of the synthesized plasticizers contained one oxygen atom, the polarity of HFCA-based plasticizers was improved, which inhibited them from migrating from the PVC matrix into nonpolar solvents. Therefore, the HFCA-based plasticizers have good potential as primary plasticizers for PVC

Dynamic Model of a Sustainable Water Resources Utilization System with Coupled Water Quality and Quantity in Tianjin City

With the development of industrial and agricultural production and the social economy, the demand for water resources has gradually increased. In this paper, based on the principles of system dynamics, a sustainable water resources utilization model with coupled water quality and quantity is established using STELLA software to assess the sustainable use of water resources. The model includes two modules: a water supply module and a water quality module. The water supply module includes four sub-systems: economy, population, water supply, and water demand. The water quality module consists of an environmental sub-system. The model is suitable for Tianjin, where water resources are scarce. Calibration is performed using data from 2013&ndash;2016, and verification is performed using data from 2017. The simulation results are good. In order to compare the sustainable use of water resources in different development scenarios in Tianjin for 2025, a sensitivity analysis is performed for each variable, and four decision variables are selected to establish four water resources use scenarios (Scenarios 1&ndash;4). The results show that, compared with scenario 1, water shortages in scenarios 2 and 3 are delayed. Scenario 4, with stable economic growth and environmental consideration, can effectively resolve the contradiction between water supply and demand in the future, and is more conducive to the improvement of water quality. Finally, based on the above research, measures to solve water resources problems are proposed, in order to provide a reference for the sustainable use of water resources and optimization of water resources allocation in Tianjin

Urine metabolomic responses to aerobic and resistance training in rats under chronic unpredictable mild stress.

BACKGROUND:It is known that bioenergetics of aerobic and resistance exercise are not the same but both can effectively improve depression. However, it is not clear whether and how different types of exercise can influence depression through the same metabolic regulatory system. Metabolomics provides a way to study the correlation between metabolites and changes in exercise and/or diseases through the quantitative analysis of all metabolites in the organism. The objective of this study was to investigate the effects of aerobic and resistance training on urinary metabolites by metabolomics analysis in a rodent model of depression. METHODS:Male Sprague-Dawley rats were given chronic unpredictable mild stress (CUMS) for eight weeks. The validity of the modeling was assessed by behavioral indices. After four weeks of CUMS, the rats that developed depression were randomly divided into a depression control group, an aerobic training group and a resistance training group. There was also a normal control group. From week 5, the rats in the exercise groups were trained for 30 min per day, five days per week, for four weeks. The urine samples were collected pre and post the training program, and analyzed by proton nuclear magnetic resonance (1H-NMR) spectroscopy. RESULTS:Both types of training improved depression-like behavior in CUMS rats. Compared with normal control, 21 potential biomarkers were identified in the urine of CUMS rats, mainly involved in energy, amino acids and intestinal microbial metabolic pathways. Common responses to the training were found in the two exercise groups that the levels of glutamine, acetone and creatine were significantly recalled (all P<0.05) Aerobic training also resulted in changes in pyruvate and trigonelline, while resistance training modified α-Oxoglutarate, citric acid, and trimethylamine oxide (all P<0.05). CONCLUSIONS:Aerobic and resistance training resulted in common effects on the metabolic pathways of alanine-aspartate-glutamate, TCA cycle, and butyric acid. Aerobic training also had effects on glycolysis or gluconeogenesis and pyruvate metabolism, while resistance training had additional effect on intestinal microbial metabolism

An Experimental Study on Mechanisms for Sediment Transformation Due to Riverbank Collapse

Riverbank erosion is a natural process in rivers that can become exacerbated by direct and indirect human impacts. Unfortunately, riverbank degradation can cause societal impacts such as property loss and sedimentation of in-stream structures, as well as environmental impacts such as water quality impact. The frequency, magnitude, and impact of riverbank collapse events in China and worldwide are forecasted to increase under climate change. To understand and mitigate the risk of riverbank collapse, experimental/field data in real conditions are required to provide robust calibration and validation of hydraulic and mathematical models. This paper presents an experimental set of tests conducted to characterize riverbank erosion and sediment transport for banks with slopes of 45&deg;, 60&deg;, 75&deg;, and 90&deg; and quantify the amount of sediments transported by the river, deposited within the bank toe or settled in the riverbed after having been removed due to erosion. The results showed interesting comprehension about the characterization of riverbank erosion and sediment transport along the river. These insights can be used for calibration and validation of new and existing numerical models