Gravitational lens magnification by Abell 1689: Distortion of the background galaxy luminosity function

Gravitational lensing magnifies the luminosity of galaxies behind the lens. We use this effect to constrain the total mass in the cluster Abell 1689 by comparing the lensed luminosities of background galaxies with the luminosity function of an undistorted field. Since galaxies are assumed to be a random sampling of luminosity space, this method is not limited by clustering noise. We use photometric redshift information to estimate galaxy distance and intrinsic luminosity. Knowing the redshift distribution of the background population allows us to lift the mass/background degeneracy common to lensing analysis. In this paper we use 9 filters observed over 12 hours with the Calar Alto 3.5m telescope to determine the redshifts of 1000 galaxies in the field of Abell 1689. Using a complete sample of 151 background galaxies we measure the cluster mass profile. We find that the total projected mass interior to 0.25h^(-1)Mpc is (0.48 +/- 0.16) * 10^(15)h^(-1) solar masses, where our error budget includes uncertainties from the photometric redshift determination, the uncertainty in the off-set calibration and finite sampling. This result is in good agreement with that found by number count and shear-based methods and provides a new and independent method to determine cluster masses.Comment: 13 pages, 10 figures. Submitted to MNRAS (10/99); Replacement with 1 page extra text inc. new section, accepted by MNRA

Formation of '3D' multiplanet systems by dynamical disruption of multiple-resonance configurations

Assuming that giant planets are formed in thin protoplanetary discs, a '3D' system can form, provided that the mutual inclination is excited by some dynamical mechanism. Resonant interactions and close planetary encounters are thought to be the primary inclination-excitation mechanisms, resulting in a resonant and non-resonant system, respectively. Here we propose an alternative formation scenario, starting from a system composed of three giant planets in a nearly coplanar configuration. As was recently shown for the case of the Solar system, planetary migration in the gas disc (Type II migration) can force the planets to become trapped in a multiply resonant state. We simulate this process, assuming different values for the planetary masses and mass ratios. We show that such a triple resonance generally becomes unstable as the resonance excites the eccentricities of all planets and planet-planet scattering sets in. One of the three planets is typically ejected from the system, leaving behind a dynamically 'hot' (but stable) two-planet configuration. The resulting two-planet systems typically have large values of semimajor axial ratios (a1/a2 < 0.3), while the mutual inclination can be as high as 70{\deg}, with a median of \sim30{\deg}. A small fraction of our two-planet systems (\sim5 per cent) ends up in the stability zone of the Kozai resonance. In a few cases, the triple resonance can remain stable for long times and a '3D' system can form by resonant excitation of the orbital inclinations; such a three-planet system could be stable if enough eccentricity damping is exerted on the planets. Finally, in the single-planet resulting systems, which are formed when two planets are ejected from the system, the inclination of the planet's orbital plane with respect to the initial invariant plane -presumably the plane perpendicular to the star's spin axis- can be as large as \sim40{\deg}.Comment: 9 pages, 5 figures, published in MNRA

Probing the distribution of dark matter in the Abell 901/902 supercluster with weak lensing

We present a weak shear analysis of the Abell 901/902 supercluster, composed of three rich clusters at z=0.16. Using a deep R-band image from the 0.5 x 0.5 degree MPG/ESO Wide Field Imager together with supplementary B-band observations, we build up a comprehensive picture of the light and mass distributions in this region. We find that, on average, the light from the early-type galaxies traces the dark matter fairly well, although one cluster is a notable exception to this rule. The clusters themselves exhibit a range of mass-to-light (M/L) ratios, X-ray properties, and galaxy populations. We attempt to model the relation between the total mass and the light from the early-type galaxies with a simple scale-independent linear biasing model. We find M/L_B=130h for the early type galaxies with zero stochasticity, which, if taken at face value, would imply Omega_m < 0.1. However, this linear relation breaks down on small scales and on scales equivalent to the average cluster separation (approximately 1 Mpc), demonstrating that a single M/L ratio is not adequate to fully describe the mass-light relation in the supercluster. Rather, the scatter in M/L ratios observed for the clusters supports a model incorporating non-linear biasing or stochastic processes. Finally, there is a clear detection of filamentary structure connecting two of the clusters, seen in both the galaxy and dark matter distributions, and we discuss the effects of cluster-cluster and cluster-filament interactions as a means to reconcile the disparate descriptions of the supercluster.Comment: 23 pages, 19 figures. ApJ, accepte

Hydrophobic and Charged Residues in the C-Terminal Arm of Hepatitis C Virus RNA-Dependent RNA Polymerase Regulate Initiation and Elongation.

The RNA-dependent RNA polymerase (RdRp) of hepatitis C virus (HCV) is essential for viral genome replication. Crystal structures of the HCV RdRp reveal two C-terminal features, a β-loop and a C-terminal arm, suitably located for involvement in positioning components of the initiation complex. Here we show that these two elements intimately regulate template and nucleotide binding, initiation, and elongation. We constructed a series of β-loop and C-terminal arm mutants, which were used for in vitro analysis of RdRp de novo initiation and primer extension activities. All mutants showed a substantial decrease in initiation activities but a marked increase in primer extension activities, indicating an ability to form more stable elongation complexes with long primer-template RNAs. Structural studies of the mutants indicated that these enzyme properties might be attributed to an increased flexibility in the C-terminal features resulting in a more open polymerase cleft, which likely favors the elongation process but hampers the initiation steps. A UTP cocrystal structure of one mutant shows, in contrast to the wild-type protein, several alternate conformations of the substrate, confirming that even subtle changes in the C-terminal arm result in a more loosely organized active site and flexible binding modes of the nucleotide. We used a subgenomic replicon system to assess the effects of the same mutations on viral replication in cells. Even the subtlest mutations either severely impaired or completely abolished the ability of the replicon to replicate, further supporting the concept that the correct positioning of both the β-loop and C-terminal arm plays an essential role during initiation and in HCV replication in general. IMPORTANCE: HCV RNA polymerase is a key target for the development of directly acting agents to cure HCV infections, which necessitates a thorough understanding of the functional roles of the various structural features of the RdRp. Here we show that even highly conservative changes, e.g., Tyr→Phe or Asp→Glu, in these seemingly peripheral structural features have profound effects on the initiation and elongation properties of the HCV polymerase

The Calar Alto Deep Imaging Survey: K-band Galaxy Number Counts

We present K-band number counts for the faint galaxies in the Calar Alto Deep Imaging Survey (CADIS). We covered 4 CADIS fields, a total area of 0.2deg^2, in the broad band filters B, R and K. We detect about 4000 galaxies in the K-band images, with a completeness limit of K=19.75mag, and derive the K-band galaxy number counts in the range of 14.25 < K < 19.75mag. This is the largest medium deep K-band survey to date in this magnitude range. The B- and R-band number counts are also derived, down to completeness limits of B=24.75mag and R=23.25mag. The K-selected galaxies in this magnitude range are of particular interest, since some medium deep near-infrared surveys have identified breaks of both the slope of the K-band number counts and the mean B-K color at K=17\sim18mag. There is, however, a significant disagreement in the K-band number counts among the existing surveys. Our large near-infrared selected galaxy sample allows us to establish the presence of a clear break in the slope at K=17.0mag from dlogN/dm = 0.64 at brighter magnitudes to dlogN/dm = 0.36 at the fainter end. We construct no-evolution and passive evolution models, and find that the passive evolution model can simultaneously fit the B-, R- and K-band number counts well. The B-K colors show a clear trend to bluer colors for K > 18mag. We also find that most of the K=18-20mag galaxies have a B-K color bluer than the prediction of a no-evolution model for an L_* Sbc galaxy, implying either significant evolution, even for massive galaxies, or the existence of an extra population of small galaxies.Comment: Accepted for A&A, 10 pages, 7 figure

The Effect of an Early Planetesimal-Driven Migration of the Giant Planets on Terrestrial Planet Formation

The migration of the giant planets due to the scattering of planetesimals causes powerful resonances to move through the asteroid belt and the terrestrial planet region. Exactly when and how the giant planets migrated is not well known. In this paper we present results of an investigation of the formation of the terrestrial planets during and after the migration of the giant planets. The latter is assumed to have occurred immediately after the dissipation of the nebular disk -- i.e. "early" with respect to the timing of the Late Heavy Bombardment (LHB). The presumed cause of our modeled early migration of the giant planets is angular mometum transfer between the planets and scattered planetesimals.Comment: Accepted for publication in Astronomy and Astrophysic

Evolution of porosity in carbide-derived carbon aerogels

Carbide-derived carbon (CDC) aerogel monoliths with very high porosity are synthesized starting from polymeric precursors. Cross-linking by platinum-catalyzed hydrosilylation of polycarbosilanes followed by supercritical drying yields preceramic aerogels. After ceramic conversion and silicon extraction in hot chlorine gas, hierarchically porous carbon materials with specific surface areas as high as 2122 m² g⁻¹ and outstanding total pore volumes close to 9 cm³ g⁻¹ are obtained. Their pore structure is controllable by the applied synthesis temperature as shown by combined nitrogen (-196 °C) and carbon dioxide (0 °C) measurements coupled with electron microscopic methods. The combination of large micropore volumes and the aerogel-type pore system leads to advanced adsorption properties due to a combination of large storage capacities and effective materials transport in comparison with purely microporous reference materials as shown by thermal response measurements

Laboratory-confirmed influenza infection and acute myocardial infarction among United States senior Veterans

BackgroundPrevious studies established an association between laboratory-confirmed influenza infection (LCI) and hospitalization for acute myocardial infarction (AMI) but not causality. We aimed to explore the underlying mechanisms by adding biological mediators to an established study design used by earlier studies.MethodsWith data on biomarkers, we used a self-controlled case-series design to evaluate the effect of LCI on hospitalization for AMI among Veterans Health Administration (VHA) patients. We included senior Veterans (age 65 years and older) with LCI between 2010 through 2015. Patient-level data from VHA electronic medical records were used to capture laboratory results, hospitalizations, and baseline patient characteristics. We defined the "risk interval" as the first 7 days after specimen collection and the "control interval" as 1 year before and 1 year after the risk interval. More importantly, using mediation analysis, we examined the role of abnormal white blood cell (WBC) and platelet count in the relationship between LCI and AMI to explore the thrombogenic nature of this association, thus potential causality.ResultsWe identified 391 hospitalizations for AMI that occurred within +/-1 year of a positive influenza test, of which 31 (31.1 admissions/week) occurred during the risk interval and 360 (3.5/per week) during the control interval, resulting in an incidence ratio (IR) for AMI admission of 8.89 (95% confidence interval [CI]: 6.16-12.84). In stratified analyses, AMI risk was significantly elevated among patients with high WBC count (IR, 12.43; 95% CI: 6.99-22.10) and high platelet count (IR, 15.89; 95% CI: 3.59-70.41).ConclusionWe confirmed a significant association between LCI and AMI. The risk was elevated among those with high WBC or platelet count, suggesting a potential role for inflammation and platelet activation in the underlying mechanism

Simple Model of Capillary Condensation in porous media

We employ a simple model to describe the phase behavior of 4He and Ar in a hypothetical porous material consisting of a regular array of infinitely long, solid, parallel cylinders. We find that high porosity geometries exhibit two transitions: from vapor to film and from film to capillary condensed liquid. At low porosity, the film is replaced by a ``necking'' configuration, and for a range of intermediate porosity there are three transitions: from vapor to film, from film to necking and from necking to a capillary condensed phase.Comment: 14 pages, 7 figure

Influenza vaccine in chronic obstructive pulmonary disease among elderly male veterans

BACKGROUND: Prior studies have established those elderly patients with chronic obstructive pulmonary disease (COPD) are at elevated risk for developing influenza-associated complications such as hospitalization, intensive-care admission, and death. This study sought to determine whether influenza vaccination could improve survival among elderly patients with COPD. MATERIALS/METHODS: This study included Veterans (age ≥ 65 years) diagnosed with COPD that received care at the United States Veterans Health Administration (VHA) during four influenza seasons, from 2012–2013 to 2015–2016. We linked VHA electronic medical records and Medicare administrative files to Centers for Disease Control and Prevention National Death Index cause of death records as well as influenza surveillance data. A multivariable time-dependent Cox proportional hazards model was used to compare rates of mortality of recipients of influenza vaccination to those who did not have records of influenza vaccination. We estimated hazard ratios (HRs) adjusted for age, gender, race, socioeconomic status, comorbidities, and healthcare utilization. RESULTS: Over a span of four influenza seasons, we included 1,856,970 person-seasons of observation where 1,199,275 (65%) had a record of influenza vaccination and 657,695 (35%) did not have a record of influenza vaccination. After adjusting for comorbidities, demographic and socioeconomic characteristics, influenza vaccination was associated with reduced risk of death during the most severe periods of influenza seasons: 75% all-cause (HR = 0.25; 95% CI: 0.24–0.26), 76% respiratory causes (HR = 0.24; 95% CI: 0.21–0.26), and 82% pneumonia/influenza cause (HR = 0.18; 95% CI: 0.13–0.26). A significant part of the effect could be attributed to “healthy vaccinee” bias as reduced risk of mortality was also found during the periods when there was no influenza activity and before patients received vaccination: 30% all-cause (HR = 0.70; 95% CI: 0.65–0.75), 32% respiratory causes (HR = 0.68; 95% CI: 0.60–0.78), and 51% pneumonia/influenza cause (HR = 0.49; 95% CI: 0.31–0.78). However, as a falsification study, we found that influenza vaccination had no impact on hospitalization due to urinary tract infection (HR = 0.97; 95% CI: 0.80–1.18). CONCLUSIONS: Among elderly patients with COPD, influenza vaccination was associated with reduced risk for all-cause and cause-specific mortality