The [alpha/Fe] Ratios in Dwarf Galaxies: Evidence for a Non-universal Stellar Initial Mass Function?

It is well established that the [alpha/Fe] ratios in elliptical galaxies increase with galaxy mass. This relation holds also for early-type dwarf galaxies, although it seems to steepen at low masses. The [alpha/Fe] vs. mass relation can be explained assuming that smaller galaxies form over longer timescales (downsizing), allowing a larger amount of Fe (mostly produced by long-living Type Ia Supernovae) to be released and incorporated into newly forming stars. Another way to obtain the same result is by using a flatter initial mass function (IMF) in large galaxies, increasing in this way the number of Type II Supernovae and therefore the production rate of alpha-elements. The integrated galactic initial mass function (IGIMF) theory predicts that the higher the star formation rate, the flatter the IMF. We have checked, by means of semi-analytical calculations, that the IGIMF theory, combined with the downsizing effect (i.e. the shorter duration of the star formation in larger galaxies), well reproduces the observed [alpha/Fe] vs. mass relation. In particular, we show a steepening of this relation in dwarf galaxies, in accordance with the available observations.Comment: 4 pages, 2 figures; to appear in the proceedings of the JENAM 2010 Symposium on Dwarf Galaxies (Lisbon, September 9-10, 2010

Suicide epidemics: The impact of newly emerging methods on overall suicide rates - A time trends study

Background: The impact of newly emerging, popular suicide methods on overall rates of suicide has not previously been investigated systematically. Understanding these effects may have important implications for public health surveillance. We examine the emergence of three novel methods of suicide by gassing in the 20 th and 21 st centuries and determine the impact of emerging methods on overall suicide rates. Methods. We studied the epidemic rises in domestic coal gas (1919-1935, England and Wales), motor vehicle exhaust gas (1975-1992, England and Wales) and barbecue charcoal gas (1999-2006, Taiwan) suicide using Poisson and joinpoint regression models. Joinpoint regression uses contiguous linear segments and join points (points at which trends change) to describe trends in incidence. Results: Epidemic increases in the use of new methods of suicide were generally associated with rises in overall suicide rates of between 23% and 71%. The recent epidemic of barbecue charcoal suicides in Taiwan was associated with the largest rise in overall rates (40-50% annual rise), whereas the smallest rise was seen for car exhaust gassing in England and Wales (7% annual rise). Joinpoint analyses were only feasible for car exhaust and charcoal burning suicides; these suggested an impact of the emergence of car exhaust suicides on overall suicide rates in both sexes in England and Wales. However there was no statistical evidence of a change in the already increasing overall suicide trends when charcoal burning suicides emerged in Taiwan, possibly due to the concurrent economic recession. Conclusions: Rapid rises in the use of new sources of gas for suicide were generally associated with increases in overall suicide rates. Suicide prevention strategies should include strengthening local and national surveillance for early detection of novel suicide methods and implementation of effective media guidelines and other appropriate interventions to limit the spread of new methods. © 2011 Thomas et al; licensee BioMed Central Ltd.published_or_final_versio

Explosion Mechanisms of Core-Collapse Supernovae

Supernova theory, numerical and analytic, has made remarkable progress in the past decade. This progress was made possible by more sophisticated simulation tools, especially for neutrino transport, improved microphysics, and deeper insights into the role of hydrodynamic instabilities. Violent, large-scale nonradial mass motions are generic in supernova cores. The neutrino-heating mechanism, aided by nonradial flows, drives explosions, albeit low-energy ones, of ONeMg-core and some Fe-core progenitors. The characteristics of the neutrino emission from new-born neutron stars were revised, new features of the gravitational-wave signals were discovered, our notion of supernova nucleosynthesis was shattered, and our understanding of pulsar kicks and explosion asymmetries was significantly improved. But simulations also suggest that neutrino-powered explosions might not explain the most energetic supernovae and hypernovae, which seem to demand magnetorotational driving. Now that modeling is being advanced from two to three dimensions, more realism, new perspectives, and hopefully answers to long-standing questions are coming into reach.Comment: 35 pages, 11 figures (29 eps files; high-quality versions can be obtained upon request); accepted by Annual Review of Nuclear and Particle Scienc

Photoemission "experiments" on holographic superconductors

We study the effects of a superconducting condensate on holographic Fermi surfaces. With a suitable coupling between the fermion and the condensate, there are stable quasiparticles with a gap. We find some similarities with the phenomenology of the cuprates: in systems whose normal state is a non-Fermi liquid with no stable quasiparticles, a stable quasiparticle peak appears in the condensed phase.Comment: 14 pages, 13 figures; v2: typos corrected and some clarification adde

Supercapacitor Degradation: Understanding Mechanisms of Cycling-Induced Deterioration and Failure of a Pseudocapacitor

Owing to a reputation for long lifetimes and excellent cycle stability, degradation in supercapacitors has largely been overlooked. In this work, we demonstrate that significant degradation in some commercial supercapacitors can in fact occur early in their life, leading to a rapid loss in capacitance, especially when utilized in full voltage range, high charge-discharge frequency applications. By using a commercial 300 F lithium-ion pseudocapacitor rated for 100,000 charge/discharge cycles as an example system, it is shown that a ∼96 % loss in capacitance over the first ∼2000 cycles is caused by significant structural and chemical change in the cathode active material (LiMn2O4, LMO). Multi-scale in-situ and ex-situ characterization, using a combination of X-ray computed tomography, Raman spectroscopy and X-ray photoelectron spectroscopy, shows that while minimal material loss (∼5.5 %), attributed to the dissolution of Mn2+, is observed, the primary mode of degradation is due to manganese charge disproportionation (Mn3+→Mn4++Mn2+) and its physical consequences (i. e. microstrain formation, particle fragmentation, loss of conductivity etc.). In contrast to prior understanding of LMO material degradation in battery systems, negligible contributions from cubic-to-tetragonal phase transitions are observed. Hence, as supercapacitors are becoming more widely utilized in real-world applications, this work demonstrates that it is vital to understand the mechanisms by which this family of devices change during their lifetimes, not just for lithium-ion pseudocapacitors, but for a wide range of commercial chemistries

Optic Nerve Head Change in Non-Arteritic Anterior Ischemic Optic Neuropathy and Its Influence on Visual Outcome

To evaluate changes in cup/disc (C/D) diameter ratios and parapapillary atrophy in patients with non-arteritic anterior ischemic optic neuropathy (NA-AION), using morphometric methods.The clinical non-interventional study included 157 patients with unilateral or bilateral NA-AION. Optic disc photographs taken from both eyes at the end of follow-up were morphometrically examined.Follow-up was 86.3±70.3 months. Horizontal and vertical disc diameters (P = 0.30;P = 0.61, respectively), horizontal and vertical C/D ratios (P = 0.47;P = 0.19,resp.), and size of alpha zone and beta zone of parapapillary atrophy (P = 0.27;P = 0.32,resp.) did not differ significantly between affected eyes and contralateral normal eyes in patients with unilateral NA-AION. Similarly, horizontal and vertical disc diameters, horizontal and vertical C/D ratios, and size of alpha zone and beta zone did not vary significantly (all P>0.05) between the unaffected eyes of patients with unilateral NA-AION and the eyes of patients with bilateral NA-AION. Optic disc diameters, C/D ratios, size of alpha zone or beta zone of parapapillary atrophy were not significantly associated with final visual outcome in the eyes affected with NA-AION (all P>0.20) nor with the difference in final visual acuity between affected eyes and unaffected eyes in patients with unilateral NA-AION (all P>0.25).NA-AION did not affect C/D ratios nor alpha zone and beta zone of parapapillary atrophy. Optic disc size was not related to the final visual acuity outcome in NA-AION

A decade in review: use of data analytics within the biopharmaceutical sector

There are large amounts of data generated within the biopharmaceutical sector. Traditionally, data analysis methods labelled as multivariate data analysis have been the standard statistical technique applied to interrogate these complex data sets. However, more recently there has been a surge in the utilisation of a broader set of machine learning algorithms to further exploit these data. In this article, the adoption of data analysis techniques within the biopharmaceutical sector is evaluated through a review of journal articles and patents published within the last ten years. The papers objectives are to identify the most dominant algorithms applied across different applications areas within the biopharmaceutical sector and to explore whether there is a trend between the size of the data set and the algorithm adopted

Semi-Holographic Fermi Liquids

We show that the universal physics of recent holographic non-Fermi liquid models is captured by a semi-holographic description, in which a dynamical boundary field is coupled to a strongly coupled conformal sector having a gravity dual. This allows various generalizations, such as a dynamical exponent and lattice and impurity effects. We examine possible relevant deformations, including multi-trace terms and spin-orbit effects. We discuss the matching onto the UV theory of the earlier work, and an alternate description in which the boundary field is integrated out.Comment: 26 pages, 4 figures; v2: typos corrected and report number adde

Dynamics of Fundamental Matter in N=2* Yang-Mills Theory

We study the dynamics of quenched fundamental matter in $\mathcal{N}=2^\ast$ supersymmetric large $N$ SU(N) Yang-Mills theory at zero temperature. Our tools for this study are probe D7-branes in the holographically dual $\mathcal{N}=2^\ast$ Pilch-Warner gravitational background. Previous work using D3-brane probes of this geometry has shown that it captures the physics of a special slice of the Coulomb branch moduli space of the gauge theory, where the $N$ constituent D3-branes form a dense one dimensional locus known as the enhancon, located deep in the infrared. Our present work shows how this physics is supplemented by the physics of dynamical flavours, revealed by the D7-branes embeddings we find. The Pilch-Warner background introduces new divergences into the D7-branes free energy, which we are able to remove with a single counterterm. We find a family of D7-brane embeddings in the geometry and discuss their properties. We study the physics of the quark condensate, constituent quark mass, and part of the meson spectrum. Notably, there is a special zero mass embedding that ends on the enhancon, which shows that while the geometry acts repulsively on the D7-branes, it does not do so in a way that produces spontaneous chiral symmetry breaking.Comment: 24 pages, 8 figures. Corrected typos, added comment about counterterm. To appear in JHE