13,902 research outputs found

    More on the Cohort-Component Model of Population Projection in the Context of HIV/AIDS: A Leslie Matrix Representation and New Estimates

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    This article presents an extension of the cohort component model of population projection (CCMPP) first formulated by Heuveline that is capable of modeling a population affected by HIV. We extend this work by developing the Leslie matrix representation of the CCMPP that greatly facilitates implementation of the model for parameter estimation and projecting. The Leslie matrix also contains information about the stable tendencies of the corresponding population, such as the stable age distribution and time to stability. We validate our reformulation of the model by comparing parameter estimates obtained through maximum likelihood and bootstrap methods to those presented by Heuveline.Africa, AIDS/HIV, cohort component method, estimation, incidence, Leslie matrices, model, prevalence

    Comparing Powers of Edge Ideals

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    Given a nontrivial homogeneous ideal Ik[x1,x2,,xd]I\subseteq k[x_1,x_2,\ldots,x_d], a problem of great recent interest has been the comparison of the rrth ordinary power of II and the mmth symbolic power I(m)I^{(m)}. This comparison has been undertaken directly via an exploration of which exponents mm and rr guarantee the subset containment I(m)IrI^{(m)}\subseteq I^r and asymptotically via a computation of the resurgence ρ(I)\rho(I), a number for which any m/r>ρ(I)m/r > \rho(I) guarantees I(m)IrI^{(m)}\subseteq I^r. Recently, a third quantity, the symbolic defect, was introduced; as ItI(t)I^t\subseteq I^{(t)}, the symbolic defect is the minimal number of generators required to add to ItI^t in order to get I(t)I^{(t)}. We consider these various means of comparison when II is the edge ideal of certain graphs by describing an ideal JJ for which I(t)=It+JI^{(t)} = I^t + J. When II is the edge ideal of an odd cycle, our description of the structure of I(t)I^{(t)} yields solutions to both the direct and asymptotic containment questions, as well as a partial computation of the sequence of symbolic defects.Comment: Version 2: Revised based on referee suggestions. Lemma 5.12 was added to clarify the proof of Theorem 5.13. To appear in the Journal of Algebra and its Applications. Version 1: 20 pages. This project was supported by Dordt College's undergraduate research program in summer 201

    A contact process with mutations on a tree

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    Consider the following stochastic model for immune response. Each pathogen gives birth to a new pathogen at rate λ\lambda. When a new pathogen is born, it has the same type as its parent with probability 1r1 - r. With probability rr, a mutation occurs, and the new pathogen has a different type from all previously observed pathogens. When a new type appears in the population, it survives for an exponential amount of time with mean 1, independently of all the other types. All pathogens of that type are killed simultaneously. Schinazi and Schweinsberg (2006) have shown that this model on Zd\Z^d behaves rather differently from its non-spatial version. In this paper, we show that this model on a homogeneous tree captures features from both the non-spatial version and the Zd\Z^d version. We also obtain comparison results between this model and the basic contact process on general graphs
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