Domain wall pinning in a circular cross-section wire with modulated diameter

Domain wall propagation in cylindrical nanowires with modulations of diameter is a key phenomenon to design physics-oriented devices, or a disruptive three-dimensional magnetic memory. This chapter presents a combination of analytical modelling and micromagnetic simulations, with the aim to present a comprehensive panorama of the physics of pinning of domain walls at modulations, when moved under the stimulus of a magnetic field or a spin-polarized current. For the sake of considering simple physics, we consider diameters of a few tens of nanometers at most, and accordingly domain walls of transverse type. Modeling with suitable approximations provides simple scaling laws, while simulations are more accurate, refining the results and defining the range of validity of the models. While pinning increases with the relative change of diameter, a key feature is the much larger efficiency of pinning at an increase of diameter upon considering current rather than field, due to the drastic decrease of current density related to the increase of diameter.Comment: 37 pages, 14 figures, overview chapte

Switching of magnetization by non-linear resonance studied in single nanoparticles

Magnetization reversal in magnetic particles is one of the fundamental issues in magnetic data storage. Technological improvements require the understanding of dynamical magnetization reversal processes at nanosecond time scales. New strategies are needed to overcome current limitations. For example, the problem of thermal stability of the magnetization state (superparamagnetic limit) can be pushed down to smaller particle sizes by increasing the magnetic anisotropy. High fields are then needed to reverse the magnetization that are difficult to achieve in current devices. Here we propose a new method to overcome this limitation. A constant applied field, well below the switching field, combined with a radio-frequency (RF) field pulse can reverse the magnetization of a nanoparticle. The efficiency of this method is demonstrated on a 20 nm cobalt particle by using the micro-SQUID technique. Other applications of this method might be nucleation or depinning of domain walls.Comment: 11 pages, 5 figure

Targeting cancer metabolism: a therapeutic window opens

Genetic events in cancer activate signalling pathways that alter cell metabolism. Clinical evidence has linked cell metabolism with cancer outcomes. Together, these observations have raised interest in targeting metabolic enzymes for cancer therapy, but they have also raised concerns that these therapies would have unacceptable effects on normal cells. However, some of the first cancer therapies that were developed target the specific metabolic needs of cancer cells and remain effective agents in the clinic today. Research into how changes in cell metabolism promote tumour growth has accelerated in recent years. This has refocused efforts to target metabolic dependencies of cancer cells as a selective anticancer strategy.Burroughs Wellcome FundSmith Family FoundationStarr Cancer ConsortiumDamon Runyon Cancer Research FoundationNational Institutes of Health (U.S.

Sur la géologie et la métallogénie des environs de Trémuson (Côtes-du-Nord)

Thirion Ch. Sur la géologie et la métallogénie des environs de Trémuson (Côtes-du-Nord). In: Bulletin de la Société française de Minéralogie, volume 52, 1-3, 1929. pp. 61-69