54 research outputs found

    The self-assembly and evolution of homomeric protein complexes

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    We introduce a simple "patchy particle" model to study the thermodynamics and dynamics of self-assembly of homomeric protein complexes. Our calculations allow us to rationalize recent results for dihedral complexes. Namely, why evolution of such complexes naturally takes the system into a region of interaction space where (i) the evolutionarily newer interactions are weaker, (ii) subcomplexes involving the stronger interactions are observed to be thermodynamically stable on destabilization of the protein-protein interactions and (iii) the self-assembly dynamics are hierarchical with these same subcomplexes acting as kinetic intermediates.Comment: 4 pages, 4 figure

    ‘The Mosques Are the Biggest Problem We’ve Got Right Now’ – Key Agent and Survivor Accounts of Engaging Mosques with Domestic and Honour-Based Violence in the United Kingdom.

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    This article considers the role of mosques in addressing domestic violence (DV) and honor-based violence (HBV) in the United Kingdom. Utilizing data extracted from interviews with 38 key agents and survivors, this article will highlight that some mosques can be difficult to engage with when attempting to raise awareness on violence against women (VAW). Participants explained that the patriarchal nature of mosques contributes to this difficulty together with their exclusion of women within organizational structures. Some mosques also deny that VAW is even a problem within their communities. This is a worrying trend as those on the pulpit often possess significant powers of influence across large congregations and are perfectly placed to help provoke dialogue on these issues. Furthermore, it adds yet another layer of inequality experienced by Muslim women that makes reporting abuse and seeking intervention that much more difficult. In the face of this resistance, this article will consider some ways in which mosques can raise awareness about VAW and where Muslim women can access support. It will also explore additional strategies and recommendations in relation to overcoming mosques unwilling to support VAW initiatives

    Hidden Voices: Disabled Women's Experiences of Violence and Support Over the Life Course

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    Violence against women is a worldwide social and human rights problem that cuts across cultural, geographic, religious, social, and economic boundaries. It affects women in countries around the world, regardless of class, religion, disability, age, or sexual identity. International evidence shows that approximately three in five women experienced physical and/or sexual violence by an intimate partner. However, across the globe, women and girls with impairments or life-limiting illnesses are more susceptible to different forms of violence across a range of environments and by different perpetrators including professionals and family members as well as partners. However, they are likely to be seriously disadvantaged in gaining information and support to escape the abusive relationships. This article stems from the United Kingdom part of a comparative study with three other countries (Austria, Germany, and Iceland) funded by the European Commission (EC; 2013-2015). It presents preliminary findings, generated from life history interviews, about disabled women's experiences of violence and access to support (both formal and informal) over their life course and their aspirations for the prevention of violence in the future. The article includes examples of impairment-specific violence that non-disabled women do not experience. By bringing the voices of disabled women into the public domain, the article will facilitate a historically marginalized group to contribute to the debate about disability, violence, and support

    Constructions of vulnerability in comparative perspective: Scottish protection policies and the trouble with "adults at risk"

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    This paper places Scottish adult support and protection (ASP) policy in the context of debates about the nature of 'vulnerability' and its usefulness as a defining concept in law and social policy. It examines the construction of 'adults at risk' in ASP policy, using a comparison with the construction of children in Scottish child protection policy, on the one hand, and women in Scottish domestic abuse policy, on the other, to illuminate the nature of the vulnerability that ASP considers itself to be addressing. It then problematises this construction, drawing both on the social model of disability and on an ethic of care. It concludes that current ASP policy remains underpinned by unhelpful assumptions about disabled people, older people and people with mental or physical health problems. A more inclusive understanding of vulnerability would be more empowering to these people and others, in policies concerned with mistreatment and abuse

    Domestic abuse: predicting, assessing and responding to risk in the Criminal Justice System and beyond

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    This chapter brings together early findings from three PhD projects on domestic abuse, each taking a different approach. The first explores the issues of underreporting and the predictors of risk; the second focuses on the police response to domestic abuse, highlighting gaps in service provision to victims; and the final project looks at specialist courts and the work of independent domestic violence advisors. This chapter cannot do justice to all three of the projects here; however, it is worth noting that, together, they form a body of research with the potential to make a significant contribution to the field. Indeed, the motivation for each of the projects is to add to current efforts to improve responses to domestic abuse within the criminal justice system and beyond. This chapter will focus on the ways in which practitioners might predict, assess, and respond to risk in relation to domestic abuse

    Gender and Educational Differences in Perception of Domestic Violence Against Women Among Libyan Migrants in Manchester.

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    Domestic violence against women (DVAW) is a worldwide phenomenon and refers to any act committed against women that results in physical and psychological harm, and coercion, loss of liberty, and deprivation. There is a dearth of research and information about the extent and prevalence of domestic violence among Libyan communities. The aim of the study was to explore community knowledge of, and attitudes toward, DVAW and to improve our understanding of the factors that influence knowledge, attitudes, and responses, particularly educational and gender differences. Using snowball sampling, we analyzed 20 semistructured interviews with Libyans living in Manchester, United Kingdom. We found gender and education-influenced participants' perception of DVAW. Men in general did not recognize DVAW as a serious social problem; noticeably, they saw it as a personal and family issue. Knowing attitudes toward DVAW is necessary for government and communities' prevention policies as attitudes influence perpetration of DVAW

    Key Agent and Survivor Recommendations for Intervention in Honour-Based Violence in the UK

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    This paper concerns recommendations for intervention in honour-based violence (“HBV”) as recommended by individuals who face such violence in their everyday lives. Utilising data extracted from interviews conducted with 30 key agents and 8 South-Asian female survivors in the UK, this paper will argue that UK public agencies are struggling to cope with how to respond to HBV. This is despite the UK government recognising shortcomings in the support for victims in the House of Commons Home Affairs Committee report in 2008. In particular, participants identified that (a) the police, healthcare, and social services are particularly poor at supporting victims; (b) public sector workers require appropriate training and awareness on HBV; (c) education on HBV and forced marriages is absent in schools, colleges, and universities; and (d) more needs to be done to engage and educate communities about HBV and where victims can access support

    Policing UK Honour-Based Abuse Crime

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    This book examines the different forms that honour-based abuse crimes take, and analyses the discretionary police practices employed when responding to these incidents. Honour-based abuse is an incident or crime involving violence, threats of violence, intimidation, coercion or abuse committed in order to protect or defend the honour of an individual, family and or community for a perceived breach of their code of behaviour. Based on unique UK police data, it includes examination of one hundred honour abuse cases and interviews with fifteen predominantly detective specialist police officers that investigate this crime. This book recognises the challenges encountered when policing honour-based abuse and offers recommendations for addressing them. It will particularly benefit police forces in England and Wales, the Home Office, scholars in gendered violence and policing and non-government organisations (charities supporting victims) by highlighting some of the issues associated with policing, partnership working arrangements and safeguarding victims of honour-based abuse crimes

    Feeling ‘like a minority…a pathology’: interpreting race from research with African and Caribbean women on violence and abuse

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    Qualitative researchers are often advised to use their emotional responses to data, and participants’ experiences are understood through those of researchers’, how this process unfolds is less clear. This paper is about role of feelings for the qualitative researcher at different stages of the process and offers strategies for working through, ‘using’ and ‘feeling together with’ participants, reflections on lived experiences. I interviewed nine African and Caribbean heritage British women about their experiences of violence and abuse where one described feeling ‘like a minority…a pathology’. This paper describes my responses to experiences of racialised and gendered intrusion in interviews, later reflection and analytic work. The paper brings recognition to a stigmatised and hidden process within qualitative interviews and data interpretation. This serves to amplify the impact of injustice and adverse experiences for participants, and researchers, and to a wider audience, and to validate its existence and emotional burden as a legitimate and crucial stage of qualitative data analysis
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