Screened thermonuclear reactions and predictive stellar evolution of detached double-lined eclipsing binaries

The low energy fusion cross sections of charged-particle nuclear reactions (and the respective reaction rates) in stellar plasmas are enhanced due to plasma screening effects. We study the impact of those effects on predictive stellar evolution simulations for detached double-lined eclipsing binaries. We follow the evolution of binary systems (pre-main sequence or main sequence stars) with precisely determined radii and masses from 1.1Mo to 23Mo (from their birth until their present state). The results indicate that all the discrepancies between the screened and unscreened models (in terms of luminosity, stellar radius, and effective temperature) are within the observational uncertainties. Moreover, no nucleosynthetic or compositional variation was found due to screening corrections. Therefore all thermonuclear screening effects on the charged-particle nuclear reactions that occur in the binary stars considered in this work (from their birth until their present state) can be totally disregarded. In other words, all relevant charged-particle nuclear reactions can be safely assumed to take place in a vacuum, thus simplifying and accelerating the simulation processes.Comment: 5 RevTex pages,no figures. Accepted for publication in Phys.Rev.

Stationary states of a nonlinear Schrödinger lattice with a harmonic trap

We study a discrete nonlinear Schrödinger lattice with a parabolic trapping potential. The model, describing, e.g., an array of repulsive Bose-Einstein condensate droplets confined in the wells of an optical lattice, is analytically and numerically investigated. Starting from the linear limit of the problem, we use global bifurcation theory to rigorously prove that – in the discrete regime – all linear states lead to nonlinear generalizations thereof, which assume the form of a chain of discrete dark solitons (as the density increases). The stability of the ensuing nonlinear states is studied and it is found that the ground state is stable, while the excited states feature a chain of stability/instability bands. We illustrate the mechanisms under which discreteness destabilizes the dark-soliton configurations, which become stable only in the continuum regime. Continuation from the anti-continuum limit is also considered, and a rich bifurcation structure is revealed

Intrinsic Energy Localization through Discrete Gap Breathers in One-Dimensional Diatomic Granular Crystals

We present a systematic study of the existence and stability of discrete breathers that are spatially localized in the bulk of a one-dimensional chain of compressed elastic beads that interact via Hertzian contact. The chain is diatomic, consisting of a periodic arrangement of heavy and light spherical particles. We examine two families of discrete gap breathers: (1) an unstable discrete gap breather that is centered on a heavy particle and characterized by a symmetric spatial energy profile and (2) a potentially stable discrete gap breather that is centered on a light particle and is characterized by an asymmetric spatial energy profile. We investigate their existence, structure, and stability throughout the band gap of the linear spectrum and classify them into four regimes: a regime near the lower optical band edge of the linear spectrum, a moderately discrete regime, a strongly discrete regime that lies deep within the band gap of the linearized version of the system, and a regime near the upper acoustic band edge. We contrast discrete breathers in anharmonic FPU-type diatomic chains with those in diatomic granular crystals, which have a tensionless interaction potential between adjacent particles, and highlight in that the asymmetric nature of the latter interaction potential may lead to a form of hybrid bulk-surface localized solutions

Dark solitons in cigar-shaped Bose-Einstein condensates in double-well potentials

We study the statics and dynamics of dark solitons in a cigar-shaped Bose-Einstein condensate confined in a double-well potential. Using a mean-field model with a non-cubic nonlinearity, appropriate to describe the dimensionality crossover regime from one to three dimensional, we obtain branches of solutions in the form of single- and multiple-dark soliton states, and study their bifurcations and stability. It is demonstrated that there exist dark soliton states which do not have a linear counterpart and we highlight the role of anomalous modes in the excitation spectra. Particularly, we show that anomalous mode eigenfrequencies are closely connected to the characteristic soliton frequencies as found from the solitons' equations of motion, and how anomalous modes are related to the emergence of instabilities. We also analyze in detail the role of the height of the barrier in the double well setting, which may lead to instabilities or decouple multiple dark soliton states.Comment: 35 pages, 12 figure

Dynamics of interacting dark soliton stripes

In the present work we examine the statics and dynamics of multiple parallel dark soliton stripes in a two-dimensional Bose-Einstein condensate. Our principal goal is to study the effect of the interaction between the stripes on the transverse instability of the individual stripes. We use a recently developed adiabatic invariant formulation to derive a quasi-analytical prediction for the stripe equilibrium position and for the Bogoliubov-de Gennes spectrum of excitations of stationary stripes. The cases of two-, three- and four-stripe states are studied in detail. We subsequently test our predictions against numerical simulations of the full two-dimensional Gross-Pitaevskii equation. We find that the number of unstable eigenmodes increases as the number of stripes increases due to (unstable) relative motions between the stripes. Their corresponding growth rates do not significantly change, although for large chemical potentials, the larger the stripe number, the larger the maximal instability growth rate. The instability induced dynamics of multiple stripe states and their decay into vortices are also investigated.Comment: 13 pages, 11 figure

Multiple atomic dark solitons in cigar-shaped Bose-Einstein condensates

We consider the stability and dynamics of multiple dark solitons in cigar-shaped Bose-Einstein condensates (BECs). Our study is motivated by the fact that multiple matter-wave dark solitons may naturally form in such settings as per our recent work [Phys. Rev. Lett. 101, 130401 (2008)]. First, we study the dark soliton interactions and show that the dynamics of well-separated solitons (i.e., ones that undergo a collision with relatively low velocities) can be analyzed by means of particle-like equations of motion. The latter take into regard the repulsion between solitons (via an effective repulsive potential) and the confinement and dimensionality of the system (via an effective parabolic trap for each soliton). Next, based on the fact that stationary, well-separated dark multi-soliton states emerge as a nonlinear continuation of the appropriate excited eigensates of the quantum harmonic oscillator, we use a Bogoliubov-de Gennes analysis to systematically study the stability of such structures. We find that for a sufficiently large number of atoms, multiple soliton states may be dynamically stable, while for a small number of atoms, we predict a dynamical instability emerging from resonance effects between the eigenfrequencies of the soliton modes and the intrinsic excitation frequencies of the condensate. Finally we present experimental realizations of multi-soliton states including a three-soliton state consisting of two solitons oscillating around a stationary one.Comment: 17 pages, 11 figure

IGF-IR cooperates with ERα to inhibit breast cancer cell aggressiveness by regulating the expression and localisation of ECM molecules

IGF-IR is highly associated with the behaviour of breast cancer cells. In ERα-positive breast cancer, IGF-IR is present at high levels. In clinical practice, prolonged treatment with anti-estrogen agents results in resistance to the therapy with activation of alternative signaling pathways. Receptor Tyrosine Kinases, and especially IGF-IR, have crucial roles in these processes. Here, we report a nodal role of IGF-IR in the regulation of ERα-positive breast cancer cell aggressiveness and the regulation of expression levels of several extracellular matrix molecules. In particular, activation of IGF-IR, but not EGFR, in MCF-7 breast cancer cells results in the reduction of specific matrix metalloproteinases and their inhibitors. In contrast, IGF-IR inhibition leads to the depletion by endocytosis of syndecan-4. Global important changes in cell adhesion receptors, which include integrins and syndecan-4 triggered by IGF-IR inhibition, regulate adhesion and invasion. Cell function assays that were performed in MCF-7 cells as well as their ERα-suppressed counterparts indicate that ER status is a major determinant of IGF-IR regulatory role on cell adhesion and invasion. The strong inhibitory role of IGF-IR on breast cancer cells aggressiveness for which E2-ERα signaling pathway seems to be essential, highlights IGF-IR as a major molecular target for novel therapeutic strategies

Dark-in-Bright Solitons in Bose-Einstein Condensates with Attractive Interactions

We demonstrate a possibility to generate localized states in effectively one-dimensional Bose-Einstein condensates with a negative scattering length in the form of a dark soliton in the presence of an optical lattice (OL) and/or a parabolic magnetic trap. We connect such structures with twisted localized modes (TLMs) that were previously found in the discrete nonlinear Schr{\"o}dinger equation. Families of these structures are found as functions of the OL strength, tightness of the magnetic trap, and chemical potential, and their stability regions are identified. Stable bound states of two TLMs are also found. In the case when the TLMs are unstable, their evolution is investigated by means of direct simulations, demonstrating that they transform into large-amplitude fundamental solitons. An analytical approach is also developed, showing that two or several fundamental solitons, with the phase shift $\pi$ between adjacent ones, may form stable bound states, with parameters quite close to those of the TLMs revealed by simulations. TLM structures are found numerically and explained analytically also in the case when the OL is absent, the condensate being confined only by the magnetic trap.Comment: 13 pages, 7 figures, New Journal of Physics (in press

Stability of dark solitons in a Bose-Einstein condensate trapped in an optical lattice

We investigate the stability of dark solitons (DSs) in an effectively one-dimensional Bose-Einstein condensate in the presence of the magnetic parabolic trap and an optical lattice (OL). The analysis is based on both the full Gross-Pitaevskii equation and its tight-binding approximation counterpart (discrete nonlinear Schr{\"o}dinger equation). We find that DSs are subject to weak instabilities with an onset of instability mainly governed by the period and amplitude of the OL. The instability, if present, sets in at large times and it is characterized by quasi-periodic oscillations of the DS about the minimum of the parabolic trap.Comment: Typo fixed in Eq. (1): cos^2 -> sin^

Vortices in a Bose-Einstein condensate confined by an optical lattice

We investigate the dynamics of vortices in repulsive Bose-Einstein condensates in the presence of an optical lattice (OL) and a parabolic magnetic trap. The dynamics is sensitive to the phase of the OL potential relative to the magnetic trap, and depends less on the OL strength. For the cosinusoidal OL potential, a local minimum is generated at the trap's center, creating a stable equilibrium for the vortex, while in the case of the sinusoidal potential, the vortex is expelled from the center, demonstrating spiral motion. Cases where the vortex is created far from the trap's center are also studied, revealing slow outward-spiraling drift. Numerical results are explained in an analytical form by means of a variational approximation. Finally, motivated by a discrete model (which is tantamount to the case of the strong OL lattice), we present a novel type of vortex consisting of two pairs of anti-phase solitons.Comment: 10 pages, 6 figure