6 research outputs found

    eQTL effects for Systemic lupus erythematosus variants

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    <p>This is a companion figure for our 2015 American Society of Human Genetics poster. Here we show the genes for which we have evidence that they are regulated by variants associated to Systemic lupus erythematosus. We show clustering of these genes and functional enrichment per cluster. We also show that the regulation of some genes is context specific. For more details, you can download our poster here: http://broad.io/BIOSeQTL</p> <p> </p

    Context-specific regulatory effects of genetic risk factors - ASHG 2015

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    <p>Using 2,116 whole blood RNA-seq samples, we have identified 10 modules that alter the effect of regulatory variants. These modules depict both celltype differences as well as cellular stimulations and were identified without any a priori knowledge on cell composition or perturbations.</p

    eQTL effects for Rheumatoid Arthritis variants

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    <p>This is a companion figure for our 2015 American Society of Human Genetics poster. Here we show the genes for which we have evidence that they are regulated by variants associated to Rheumatoid Arthritis. We show clustering of these genes and functional enrichment per cluster. We also show that the regulation of some genes is context specific. For more details, you can download our poster here: http://broad.io/BIOSeQTL</p

    eQTL effects for Celiac Disease variants

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    <p>This is a companion figure for our 2015 American Society of Human Genetics poster. Here we show the genes for which we have evidence that they are regulated by variants associated to Celiac Disease. We show clustering of these genes and functional enrichment per cluster. We also show that the regulation of some genes is context specific. For more details, you can download our poster here: http://broad.io/BIOSeQTL</p> <p> </p

    eQTL effects for Multiple sclerosis variants

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    <p>This is a companion figure for our 2015 American Society of Human Genetics poster. Here we show the genes for which we have evidence that they are regulated by variants associated to eQTL effects for Multiple sclerosis variants. We show clustering of these genes and functional enrichment per cluster. We also show that the regulation of some genes is context specific. For more details, you can download our poster here: http://broad.io/BIOSeQTL</p

    eQTL effects for Type 1 diabetes variants

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    <p>This is a companion figure for our 2015 American Society of Human Genetics poster. Here we show the genes for which we have evidence that they are regulated by variants associated to Type 1 diabetes. We show clustering of these genes and functional enrichment per cluster. We also show that the regulation of some genes is context specific. For more details, you can download our poster here: http://broad.io/BIOSeQTL</p
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