Central delivery system for dialysis concentrates by gravity and computer control

SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

L'EVALUATION ET L'AMELIORATION DE LA QUALITE DES SOINS INFIRMIERS

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Description of a central proportioning and delevery systems for bicarbonate dialysis

info:eu-repo/semantics/publishe

Hypoxemia, leukopenia and complement activation with large surface hemodialysers: comparison of cellulose acetate with CuprophanR

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Description of a central proportioning and delivery system for bicarbonate dialysis.

Replacement of acetate by bicarbonate in dialysate has been proposed to reduce morbidity during hemodialysis sessions with large-area artificial kidneys. The routine use of such a dialysate raises numerous technical problems which have already been discussed by Sargent et al: (1) accuracy of proportioning of bicarbonate dialysate to achieve a controlled bicarbonate concentration coupled with the monitoring of multiple-stream system; relative insolubility of bicarbonate; (3) stability of concentrated sodium bicarbonate; (4) bacteriostatic properties of these solutions. These problems were solved in an individual three-component dialysate system (Drake-Willok 4015) but although this procedure could theoretically be conversed to a central delivery system, bicarbonate dialysate has not been routinely used in this application since stability of such a dialysate in tanks and long tubings have to be assessed. A system is described in which these problems are solved and which is able to automatically produce bicarbonate dialysate on a large scale, i.e. for 30 simultaneous dialyses.Journal ArticleSCOPUS: ar.jinfo:eu-repo/semantics/publishe

Complement activation and leucopenia on cellulosic haemodialyzers: influence of the membrane area and role of hydroxyl moietics

We analysed the impact of the area of the dialysis membrane and of its content in hydroxyl moieties on the magnitude of haemodialysis-induced complement activation and leucopenia. First, in five patients successively treated with cellulose acetate membranes of different areas, we found that increase of the area results in an increase in complement activation determined by C3a levels before and at 15 min of dialysis. The levels of leucopenia were similarly affected, and a significant correlation was found between complement activation and leucopenia (r = 0.89, P less than 0.05). When we compared the biocompatibility characteristics of a dialyser made of saponified cellulose ester with those of two dialysers made of cellulose acetate, we found that index of complement activation (18.1 +/- 2 vs 9.9 +/- 1.1 and 11.5 +/- 1.1, P less than 0.01) as well as index of leucopenia (69 +/- 4 vs 40 +/- 2 and 37 +/- 3, P less than 0.001) were significantly higher on the saponified cellulose ester dialysers suggesting that hydroxyl groups of cellulosic membranes play an important role in the pathophysiology of dialysis-induced changes.Comparative StudyJournal ArticleSCOPUS: ar.jinfo:eu-repo/semantics/publishe

From evaluation to improvement of quality of care

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Is uremic morbidity more related to BUN than to middle molecule clearance?

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Membrane-related eosinophilia in hemodialysis

The high prevalence (10 to 25%) of blood eosinophilia in patients on maintenance hemodialysis is well established. Because esosinophils are considered to modulate local immediate hypersensitivity reaction, dialysis eosinophilia could be a manifestation of an allergic response to hemodialysis-specific antigen exposure. Among many substances that may involve hypersensitivity in hemodialysis, cuprophane membranes have been implicated. We investigated the possible role of the dialysis membrane in this syndrome by switching hemodialysis patients with persistent eosinophilia from their usual cellulose membranes to polyacrylonitrile membranes.Clinical TrialControlled Clinical TrialJournal ArticleSCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

Blood urea nitrogen and morbidity in dialysed patients

info:eu-repo/semantics/publishe