Systematic review of the results of kidney transplantation in patients with aortoiliac revascularization surgery

Enfermedad renal crónica; Trasplante renal; Cirugía de revascularizaciónChronic kidney disease; Kidney transplantation; Revascularization surgeryMalaltia renal crònica; Trasplantament renal; Cirurgia de revascularitzacióIntroducción: la enfermedad renal crónica (ERC) acelera el proceso de arterioesclerosis, lo que incrementa la prevalencia de enfermedad arterial periférica (EAP). El objetivo de esta revisión sistemática es evaluar los resultados del trasplante renal en pacientes sometidos a cirugía abierta de revascularización del sector aortoilíaco por arteriopatía crónica de las extremidades inferiores. Material y métodos: revisión sistemática según las recomendaciones QUOROM de artículos en PubMed y Cochrane, en español e inglés, que incluían pacientes con ERC y cirugía abierta de revascularización del sector aortoilíaco en el pasado o como indicación previa a un trasplante renal. Los artículos incluidos describían complicaciones inmediatas, supervivencia del injerto y supervivencia del paciente después del trasplante renal. Resultados: la búsqueda generó 253 artículos. Tras la revisión se seleccionaron 8 artículos que incluían 101 pacientes, de los que el 84,2 % fueron trasplantados. La incidencia de complicaciones tras la revascularización fue del 25,9 % y la incidencia de complicaciones tras el trasplante renal fue del 28,2 %. La mediana de seguimiento fue de 22 meses (rango: 6,7 a 71). La supervivencia del injerto renal fue del 80 % y la del paciente fue del 90,5 % al final del seguimiento. Conclusión: la coexistencia de enfermedad arterial y renal no debe considerarse un obstáculo para la realización de un trasplante renal. Los datos publicados hasta el momento muestran resultados satisfactorios en la supervivencia del injerto y del paciente.Introduction: chronic kidney disease (CKD) increases and accelerates the arterial calcification process, increasing the prevalence of peripheral arterial disease in these patients. The aim of this systematic review is to evaluate the results of kidney transplantation in patients who have undergone open revascularization surgery in the aorto-iliac sector for chronic lower limb arteriopathy. Material and methods: systematic review, following QUORUM recommendations, of articles in PubMed and Cochrane, in English or Spanish, which include patients with CKD, who have undergone open revascularization surgery of the aorto-iliac sector in the past or as a prior indication to kidney transplantation. Articles included described immediate complications, graft survival and patient survival after kidney transplantation. Results: the search generated 253 articles and after the systematic review, 8 articles that included, 101 patients were selected, 84.2 % of whom were transplanted. Complications of revascularization surgery were 25.9 % and complications of kidney transplantation were 28.2 %. Median follow-up was 22 months (range: 6.7 to 71). Graft survival was 80 % and patient survival was 100 % at the end of follow-up. Conclusion: the coexistence of vascular and kidney disease should not be an obstacle to performing a kidney transplantation. Since the data published so far shows satisfactory results in graft and patient survival

Prevalence of Peripheral Arterial Disease and Associated Vascular Risk Factors in 65-Years-Old People of Northern Barcelona

Asintomático; Factores de riesgo cardiovascular; PrevalenciaAsimptomàtic; Factors de risc cardiovascular; PrevalençaAsymptomatic; Cardiovascular risk factors; PrevalenceObjective: To determine the prevalence and risk factors associated with peripheral arterial disease (PAD) in Northern Barcelona at 65 years of age. Methods: A single-center, cross-sectional study, including males and females 65 years of age, health care cardholders of Barcelona Nord. PAD was defined as an ankle–brachial index (ABI) < 0.9. Attending subjects were evaluated for a history of common cardiovascular risk factors. A REGICOR score was obtained, as well as a physical examination and anthropometric measurements. Results: From November 2017 to December 2018, 1174 subjects were included: 479 (40.8%) female and 695 (59.2%) male. Overall prevalence of PAD was 6.2% (95% CI: 4.8–7.6%), being 7.9% (95% CI: 5.9–9.9%) in males and 3.8% (95% CI: 2.1–5.5%) in females. An independent strong association was seen in male smokers and diabetes, with ORs pf 7.2 (95% CI: 2.8–18.6) and 1.8 (95% CI: 1.0–3.3), respectively, and in female smokers and hypertension, with ORs of 5.2 (95% CI: 1.6–17.3) and 3.3 (95% CI: 1.2–9.0). Male subjects presented with higher REGICOR scores (p < 0.001). Conclusion: Higher-risk groups are seen in male subjects with a history of smoking and diabetes and female smokers and arterial hypertension, becoming important subgroups for our primary healthcare centers and should be considered for ABI screening programs.This work was logistically supported by the PERIS 2016–2020 medical research grant from Generalitat de Catalunya (Spain). Expedient Number SLT002/16/00441