Coupling vortex dynamics with collective excitations in Bose-Einstein Condensates

Here we analyze the collective excitations as well as the expansion of a trapped Bose-Einstein condensate with a vortex line at its center. To this end, we propose a variational method where the variational parameters have to be carefully chosen in order to produce reliable results. Our variational calculations agree with numerical simulations of the Gross-Pitaevskii equation. The system considered here turns out to exhibit four collective modes of which only three can be observed at a time depending of the trap anisotropy. We also demonstrate that these collective modes can be excited using well established experimental methods such as modulation of the s-wave scattering length

Deeply rooted but still striving for a role: the Portuguese Freguesias under reform

[Excerpt] In political science, the debate about the size of local jurisdictions for the exercise of democratic governance has gained significant traction in recent years. The discussion frequently pits the supporters of the “small is beautiful” motto against the advocates of the “large is lively” argument (Denters et al. 2014)

Association or Causation? Exploring the Oral Microbiome and Cancer Links

Several epidemiological investigations have found associations between poor oral health and different types of cancer, including colorectal, lung, pancreatic, and oral malignancies. The oral health parameters underlying these relationships include deficient oral hygiene, gingival bleeding, and bone and tooth loss. These parameters are related to periodontal diseases, which are directly and indirectly mediated by oral bacteria. Given the increased accessibility of microbial sequencing platforms, many recent studies have investigated the link between the oral microbiome and these cancers. Overall, it seems that oral dysbiotic states can contribute to tumorigenesis in the oral cavity as well as in distant body sites. Further, it appears that certain oral bacterial species can contribute to carcinogenesis, in particular, Fusobacterium nucleatum and Porphyromonas gingivalis, based on results from epidemiological as well as mechanistic studies. Yet, the strength of the findings from these investigations is hampered by the heterogeneity of the methods used to measure oral diseases, the treatment of confounding factors, the study design, the platforms employed for microbial analysis, and types of samples analyzed. Despite these limitations, there is an overall indication that the presence of oral dysbiosis that leads to oral diseases may directly and/or indirectly contribute to carcinogenesis. Proper methodological standardized approaches should be implemented in future epidemiological studies as well as in the mechanistic investigations carried out to explore these results. © International & American Associations for Dental Research 202

Fracturas dos ossos longos “um projecto para o futuro”

Os autores dividem as fracturas dos ossos longos em níveis; classificam as fracturas dos diferentes níveis; traçam normas de conduta terapêutica para cada fractura, e propõem um método de classificação dos resultados com base em parâmetros que avaliam todo um membro, e não apenas o aspecto radiológico da fractura. Pretendem, desta forma, uniformizar a classificação das fracturas e dos resultados, de modo a tornar possível a computorização das histórias clínicas

Voice, responsiveness, and alternative policy venues: an analysis of citizen complaints against the local government to the national Ombudsman

The Ombudsman is one of the most relevant and institutionalized tools to give voice to citizens, so they can express their dissatisfaction with local public services. The literature has yet to produce a systematic explanation for the variation in complaints to the national Ombudsman. This article uses classic literature from public administration and public policy to consider arguments of voice, responsiveness and alternative policy venues concerning the role of the Ombudsman in citizen complaints against local governments. Data on all 2139 citizen complaints submitted to the Ombudsman in Portugal (2012–2015) are analyzed using negative binomial regression models. Policy implications drawn from the results show not only that the presence of alternative voice venues reduces the number of complaints to the national Ombudsman but also that context matters. Local politics stimulates civic engagement and difficult local conditions, such as unemployment, crime, and aging populations, activate citizens to resort to the Ombudsman.This article is part of a research project financially supported by the Fundaç~ao Francisco Manual dos Santos (FFMS), entitled “Qualidade da Governaç~ao Local.” Antonio Tavares acknowledges the Research Center in Political Science (UIDB/CPO/00758/2020), University of Minho/University of Evora supported by the Portuguese Foundation for Science and Technology (FCT) and the Portuguese Ministry of Education and Science through national funds. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the Fundaç~ao Francisco Manuel dos Santos and the Portuguese Science and Technology Foundatio

Assessing the intensity of cooperation: a study of joint delegation of municipal functions to inter-municipal associations

Talking is cheap, at least in the short term; elected officials may profess their preferences for IMC and yet deny IMA organisations the necessary resources to fulfil their missions. Driven by a focus on revealed preferences for inter-municipal cooperation, the article aims to answer two questions: Why do some IMA exhibit a high level of commitment on the part of their local government members whereas others remain underutilised, reflecting a choice by local governments to retain these responsibilities themselves? How does this commitment to IMAs vary over time? We use data from 25 IMAs over a 10-year period (2008–2018) in Portugal to assess the intensity of cooperation among Portuguese local governments through stand-alone organisations. The panel analysis regression supports the hypotheses that a larger number of local governments involved in IMAs and higher levels of heterogeneity among them make cooperation more difficult. In contrast, longer interaction in IMAs reinforces the intensity of cooperation.This work was supported by the Research Centre for Political Science (UIDB/CPO/ 00758/2020), University of Minho/University of Évora, supported by the Portuguese Foundation for Science and Technology (FCT) and the Portuguese Ministry of Education and Science

Social Plasticity Relies on Different Neuroplasticity Mechanisms across the Brain Social Decision-Making Network in Zebrafish

Social living animals need to adjust the expression of their behavior to their status within the group and to changes in social context and this ability (social plasticity) has an impact on their Darwinian fitness. At the proximate level social plasticity must rely on neuroplasticity in the brain social decision-making network (SDMN) that underlies the expression of social behavior, such that the same neural circuit may underlie the expression of different behaviors depending on social context. Here we tested this hypothesis in zebrafish by characterizing the gene expression response in the SDMN to changes in social status of a set of genes involved in different types of neural plasticity: bdnf, involved in changes in synaptic strength; npas4, involved in contextual learning and dependent establishment of GABAergic synapses; neuroligins (nlgn1 and nlgn2) as synaptogenesis markers; and genes involved in adult neurogenesis (wnt3 and neurod). Four social phenotypes were experimentally induced: Winners and Losers of a real-opponent interaction; Mirror-fighters, that fight their own image in a mirror and thus do not experience a change in social status despite the expression of aggressive behavior; and non-interacting fish, which were used as a reference group. Our results show that each social phenotype (i.e., Winners, Losers, and Mirror-fighters) present specific patterns of gene expression across the SDMN, and that different neuroplasticity genes are differentially expressed in different nodes of the network (e.g., BDNF in the dorsolateral telencephalon, which is a putative teleost homolog of the mammalian hippocampus). Winners expressed unique patterns of gene co-expression across the SDMN, whereas in Losers and Mirror-fighters the co-expression patterns were similar in the dorsal regions of the telencephalon and in the supracommissural nucleus of the ventral telencephalic area, but differents in the remaining regions of the ventral telencephalon. These results indicate that social plasticity relies on multiple neuroplasticity mechanisms across the SDMN, and that there is not a single neuromolecular module underlying this type of behavioral flexibility.FCT fellowships: (SFRH/BD/44848/2008, SFRH/BD/89072/2012)