29,846 research outputs found

    Spectroscopy of Seven Cataclysmic Variables with Periods Above Five Hours

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    We present spectroscopy of seven cataclysmic variable stars with orbital periods P(orb) greater than 5 hours, all but one of which are known to be dwarf novae. Using radial velocity measurements we improve on previous orbital period determinations, or derive periods for the first time. The stars and their periods are TT Crt, 0.2683522(5) d; EZ Del, 0.2234(5) d; LL Lyr, 0.249069(4) d; UY Pup, 0.479269(7) d; RY Ser, 0.3009(4) d; CH UMa, 0.3431843(6) d; and SDSS J081321+452809, 0.2890(4) d. For each of the systems we detect the spectrum of the secondary star, estimate its spectral type, and derive a distance based on the surface brightness and Roche lobe constraints. In five systems we also measure the radial velocity curve of the secondary star, estimate orbital inclinations, and where possible estimate distances based on the MV(max) vs.P(orb) relation found by Warner. In concordance with previous studies, we find that all the secondary stars have, to varying degrees, cooler spectral types than would be expected if they were on the main sequence at the measured orbital period.Comment: 25 pages, 2 figures, accepted for Publications of the Astronomical Society of the Pacifi

    Physics of Rheologically-Enhanced Propulsion: Different Strokes in Generalized Stokes

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    Shear-thinning is an important rheological property of many biological fluids, such as mucus, whereby the apparent viscosity of the fluid decreases with shear. Certain microscopic swimmers have been shown to progress more rapidly through shear-thinning fluids, but is this behavior generic to all microscopic swimmers, and what are the physics through which shear-thinning rheology affects a swimmer's propulsion? We examine swimmers employing prescribed stroke kinematics in two-dimensional, inertialess Carreau fluid: shear-thinning "Generalized Stokes" flow. Swimmers are modeled, using the method of femlets, by a set of immersed, regularized forces. The equations governing the fluid dynamics are then discretized over a body-fitted mesh and solved with the finite element method. We analyze the locomotion of three distinct classes of microswimmer: (1) conceptual swimmers comprising sliding spheres employing both one- and two-dimensional strokes, (2) slip-velocity envelope models of ciliates commonly referred to as "squirmers" and (3) monoflagellate pushers, such as sperm. We find that morphologically identical swimmers with different strokes may swim either faster or slower in shear-thinning fluids than in Newtonian fluids. We explain this kinematic sensitivity by considering differences in the viscosity of the fluid surrounding propulsive and payload elements of the swimmer, and using this insight suggest two reciprocal sliding sphere swimmers which violate Purcell's Scallop theorem in shear-thinning fluids. We also show that an increased flow decay rate arising from shear-thinning rheology is associated with a reduction in the swimming speed of slip-velocity squirmers. For sperm-like swimmers, a gradient of thick to thin fluid along the flagellum alters the force it exerts upon the fluid, flattening trajectories and increasing instantaneous swimming speed.Comment: 22 pages, 28 figure

    Reconstitution of T cell receptor signaling in ZAP-70-deficient cells by retroviral transduction of the ZAP-70 gene.

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    A variant of severe combined immunodeficiency syndrome (SCID) with a selective inability to produce CD8 single positive T cells and a signal transduction defect in peripheral CD4+ cells has recently been shown to be the result of mutations in the ZAP-70 gene. T cell receptor (TCR) signaling requires the association of the ZAP-70 protein tyrosine kinase with the TCR complex. Human T cell leukemia virus type I-transformed CD4+ T cell lines were established from ZAP-70-deficient patients and normal controls. ZAP-70 was expressed and appropriately phosphorylated in normal T cell lines after TCR engagement, but was not detected in T cell lines from ZAP-70-deficient patients. To determine whether signaling could be reconstituted, wild-type ZAP-70 was introduced into deficient cells with a ZAP-70 retroviral vector. High titer producer clones expressing ZAP-70 were generated in the Gibbon ape leukemia virus packaging line PG13. After transduction, ZAP-70 was detected at levels equivalent to those observed in normal cells, and was appropriately phosphorylated on tyrosine after receptor engagement. The kinase activity of ZAP-70 in the reconstituted cells was also appropriately upregulated by receptor aggregation. Moreover, normal and transduced cells, but not ZAP-70-deficient cells, were able to mobilize calcium after receptor ligation, indicating that proximal TCR signaling was reconstituted. These results indicate that this form of SCID may be corrected by gene therapy

    Geological and 40Ar/39Ar geochronological constraints on the timing of quartz vein formation in Meguma Group lode-gold deposits, Nova Scotia

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    The results of geological and 40Ar/39Ar geochronological investigations of several gold districts hosted by the Meguma Group are presented. Observations at both the macro- (deposit to ore zone) and micro- (hand sample to thin section) scale indicate that quartz vein formation followed major Acadian folding and metamorphism (ca. 400 ±10 Ma) and was broadly coincident with mafic-felsic magmatism at ca. 370 Ma. 40Ar/39Ar analyses of vein-fill mica and amphibole from the Beaver Dam, Moose River, Fifteen Mile Stream, Upper Seal Harbour and Caribou deposits indicate ages of ca. 380 Ma to ca. 362 Ma. The age data are interpreted to reflect discrete hydrothermal events with rapid cooling following crystallization of vein constituents. The age data do not reflect either variable amounts of resetting by later granitic intrusions or diachronous cooling. Genetic models that interpret the generation of the auriferous quartz veins as either before or during major Acadian folding are considered to be inconsistent with the present results. Instead, a model is favored that interprets quartz vein formation in the context of continued transpression of the Meguma Terrane following regional folding and metamorphism. RÉSUMÉ On présente les résultats d'études géologiques et géochronologiques [40Ar/39Ar] effectuées dans plusieurs districts aurifères au sein du Groupe de Meguma. Des observations tant macroscopiques (du gite à la zone de minéral) que microscopiques (de l'échantillon à la lame mince) indiquent que la formation des veines de quartz suivit un métamorphisme et un plissement majeurs acadiens (env. 400 ± 10 Ma) et coiincida d'une facon générale avec unmagmatisme mafique à felsique vers 370 Ma. Des analyses 40Ar/39Ar effectuées sur des micas et des amphiboles de remplissages de veine provenant des gites de Beaver Dam, Moose River, Fifteen Mile Stream, Upper Seal Harbour et Caribou révèlent des âges aux environs de 380 à 362 Ma. On interprète ces données d 'âge comme le reflet d'épisodes hydrothèrmaux distincts avec un refroidissement rapide suite à la cristallisation des constituants filoniens. Ces données ne reflètent ni un degré variable de remise à ziro par des intrusions granitiques ultérieures, ni un refroidissement diachrone. On considere que les modèles genetiques interprétant la formation des veines de quartz auriferes comme precedent ou ayant eu lieu pendant le plissement majeur acadien, sont en contradiction avec les resultats actuels. En leur lieu, on favorise un modèle qui interprète la formation des veines de quartz dans le contexte d'une transpression continue de la Lanière de Méguma à la suite d'un plissement et d'un métamorphisme régionaux. [Traduit par le journal

    Non-Traditional and Non-Invasive Approaches in Facial Rejuvenation: A Brief Review

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    While injectables, lasers, and surgical interventions have traditionally been used to reverse the changes associated with facial aging, other alternative therapies such as facial acupuncture and facial exercises are now being studied for facial rejuvenation. In this paper, we both summarize the concepts of facial acupuncture and facial exercises, and review seven studies that evaluate the efficacy of these modalities. Data from these studies suggest that both facial acupuncture and facial exercises have the potential to improve the skin laxity, wrinkle length, muscle thickness, and pigmentary changes associated with aging. Patients frequently reported improvement and experienced very few side effects. However, further research is necessary before these modalities are widely accepted as eective by the medical community, though the results of these studies may ultimately make providers less hesitant when patients seek out these services

    Non-Traditional and Non-Invasive Approaches in Facial Rejuvenation: A Brief Review

    Get PDF
    While injectables, lasers, and surgical interventions have traditionally been used to reverse the changes associated with facial aging, other alternative therapies such as facial acupuncture and facial exercises are now being studied for facial rejuvenation. In this paper, we both summarize the concepts of facial acupuncture and facial exercises, and review seven studies that evaluate the efficacy of these modalities. Data from these studies suggest that both facial acupuncture and facial exercises have the potential to improve the skin laxity, wrinkle length, muscle thickness, and pigmentary changes associated with aging. Patients frequently reported improvement and experienced very few side effects. However, further research is necessary before these modalities are widely accepted as effective by the medical community, though the results of these studies may ultimately make providers less hesitant when patients seek out these services
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