Распространенность дислипидемии среди населения Pеспублики Mолдова (предварительные данные)

Introduction. Dyslipidemias are among the most important modifiable risk factors associated with cardiovascular pathology. Materials and methods. The preliminary results of the observational, cross-sectional study conducted from February 2020 to January 2023 are presented. The prevalence of dyslipidemia and the lipid profile in a sample of 728 participants from rural and urban environments were analyzed. Results: In a group of participants with a mean age of 47.14 ± 12.65 years, it was observed that elevated LDL- cholesterol and decreased HDL-cholesterol levels were the most frequent abnormal lipid parameters in men, and in women isolated elevation of LDL-cholesterol was often recorded. Conclusions: The study emphasizes the importance of early screening in apparently healthy populations. Early diagnosis may identify high-risk population groups, where early intervention may lead to avoidance of later complications related to dyslipidemia.Introducere . Dislipidemiile sunt printre cei mai importanți factor de risc modificabili asociați cu patologia cardiovasculară. Materiale și metode. Sunt prezentate rezultatele preliminare a studiului observațional, transversal, desfășurat din februarie 2020 până ianuarie 2023. A fost analizată prevalența dislipidemiei și profilul lipidic la nivelul unui eșantion de 728 de participanți din mediu rural și urban. Rezultate: Într-un grup de participanți cu vârsta medie de 47,14 ± 12,65 ani s-a observat că nivelurile crescute de LDL-colesterol și scăzute de HDL-colesterol au fost cei mai frecvenți parametri lipidici anormali la bărbați, iar la femei mai des s-a înregistrat elevarea izolată a LDL-colesterol. Concluzii: Studiul subliniază importanța screening-ului precoce în populațiile aparent sănătoase. Diagnosticul timpuriu poate evidenția grupurile de populație cu risc crecut, în care intervenția anticipată poate duce la evitarea complicațiilor ulterioare legate de dislipidemie.Введение. Дислипидемии являются одними из наиболее важных модифицируемых факторов риска, связанных с сердечно-сосудистой патологией. Материалы и методы. Представлены предварительные результаты наблюдательного перекрестного исследования, проведенного с февраля 2020 г. по январь 2023 г. Проанализированы распространенность дислипидемии и липидный профиль в выборке из 728 участников из сельской и городской местности. Результаты: В группе участников со средним возрастом 47,14 ± 12,65 лет наблюдалось, что повышенный уровень холестерина ЛПНП и снижение уровня холестерина ЛПВП были наиболее частыми аномальнымипоказателями липидов у мужчин, а у женщин наиболее часто регистрировалось изолированное повышение уровня ЛПНП.Выводы: Исследование подчеркивает важность раннего скрининга среди практически здоровых групп населения. Ранняя диагностика может выявить группы населения высокого риска, где раннее вмешательство может привести к предотвращению последующих осложнений, связанных с дислипидемией

ADSORPTION WAVE OF VANADIUM COMPLEX WITH 2,3–DIHYDROXYBENZALDEHYDE

The polarographic behavior of the complex formed by V(V) and 2,3–dihydroxybenzaldehyde (2,3–DHBA) in the solution containing acetate buffer (pH 5,2) has been investigated. By means of a.c. polarography, chronovoltammetry and other techniques, it has been shown that the electrode process is complicated by the adsorption of 2,3-DHBA and its vanadium complex. The kinetic and adsorption parameters of the electrode process have been determined: adsorption equilibrium constant B= 1,32⋅105 mol-1⋅dm3, the attraction constant γ = 1,2, the maximum surface concentration Гmax = 9,10⋅10-11 mol⋅ cm-2; the share of the electrode surface occupied by one particle of the adsorbed complex S = 1,81 nm2 and the free adsorption energy ΔG = - 39,1 kJ· mol-1

CATALYTIC WAVE OF CHLORATE IONS IN THE PREZENCE OF THE MOLYBDENUM (VI) - 2,3-DIHYDROXYBENZALDEHYDE COMPLEX

The polarographic catalytic current in acid solutions of Mo(VI), 2,3-dihydroxybenzaldehyde (2,3-DHBA) and chlorate ions has been investigated. The scheme of reactions taking place in the solutions and on the electrode has been elaborated. The increase of the catalytic current is explained by the formation of the active intermediate complex [Mo(V)×2,3-DHBA (ClO3-)]. The rate constant of formation for the active intermediate complex K = 2.5 × 106 mol-1 × dm3 × s-1, the activation energy of reaction Ea=14.0 kcal×mol-1 and the activation entropy ∆Sa¹= -28.3 e.u. have also been determined

THE INFLUENCE OF THIOSEMICARBAZONE 2,3-DIHYDROXYBENZALDEHYDE ON CATALYTIC CURRENTS IN THE SYSTEM MOLYBDENUM (VI) – POTASSIUM CHLORATE IN ACID SULFATE SOLUTIONS

The polarographic catalytic current in acid solutions of Mo(VI), thiosemicarbazone 2,3-dihydroxybenzaldehyde (TSC 2,3-DHBA) and chlorate ions has been investigated. The scheme of reactions, taking place in the solutions and on the electrode, has been proposed. The increase of the catalytic current is explained by the formation of an active intermediate complex [Mo(V)×TSC 2,3-DHBA (ClO-3)]. The rate constant of this complex formation K = 2.56 × 106 mol-1×dm3×s-1, the activation energy Ea = 15.9 kcal×mol-1 and the reaction activation entropy ∆Sa¹ = -23.5 e.u. have been calculated

CHARACTERISTICS OF REFUSALS IN LOW-VOLTAGE DISTRIBUTION SYSTEMS

This paper focuses on the determination of the characteristics of refusals in low voltage electrical distribution systems. In order to solve this problem, the phenomena of occurrence of refusals in low-voltage electrical distribution systems, conditioned by different influencing factors, processed and mathematically modelled. The main results of the research consist in establishing the static characteristics of the refusals, the mathematical models that determine the occurrence of the cause phenomena and the parameters that characterize the distributions of the refusals, depending on the occurrence per system, depending on the occurrence per season, depending of interruptions duration and the number of affected consumers. The significance of the results obtained consists in solving a number of problems faced by the operating services of electrical distribution systems, concerning the assurance of reliability of operation, providing the possibility of forecasting and preventing the occurrence of the phenomena of occurrence of refusals, which enable the justified planning of prophylactic measures and ensuring the reliability level

TO THE EQUILIBRIUM MODEL CHOICE IN HETEROGENEOUS AQUEOUS SYSTEMS. 1. THEORETICAL BASIS IN THE CASE OF TWO COEXISTING SOLID PHASES

An approach has been developed to determine the equilibrium model in heterogeneous aqueous systems containing a mixture of solid phases from the initial composition of the heterogeneous mixture and the equilibrium values of the pH. This approach allows to significantly reduce the quantity of measured data, properly for solubility measurements. By using the new deduced equations it is possible to determine the solubility products of precipitates on the basis of the known composition of initial mixtures and pH values of saturated solutions avoiding some difficult experimental solubility measurements. The derived relations are useful for solving both direct and indirect equilibrium problems