About approaches to creation of all-Russian quality assurance agencies register

RF-market of service on education quality assurance and independent accreditation of universities is only entering into a phase of active development. Regulation of this market is an integral requirement of its prosperity. That is why the project developed in the framework of Federal Education Development Programme – model of All-Russian Quality Assurance Agencies Register has evoked interest not only in Russia but also of international experts in quality assurance. In Europe the quality assurance agencies actively use in their work principles of publicity and openness of assessment conducting. Their work is regulated by European Register of Quality Assurance Agencies (EQAR). In this article is described the model of All-Russian Quality Assurance Agencies Register and the ways of its implementation

Cobalt Ferrite Nanoparticles for Tumor Therapy: Effective Heating versus Possible Toxicity

Magnetic nanoparticles (MNPs) are widely considered for cancer treatment, in particular for magnetic hyperthermia (MHT). Thereby, MNPs are still being optimized for lowest possible toxicity on organisms while the magnetic properties are matched for best heating capabilities. In this study, the biocompatibility of 12 nm cobalt ferrite MNPs, functionalized with citrate ions, in different dosages on mice and rats of both sexes was investigated for 30 days after intraperitoneal injection. The animals’ weight, behavior, and blood cells changes, as well as blood biochemical parameters are correlated to histological examination of organs revealing that cobalt ferrite MNPs do not have toxic effects at concentrations close to those used previously for efficient MHT. Moreover, these MNPs demonstrated high specific loss power (SLP) of about 400 W g−1. Importantly the MNPs retained their magnetic properties inside tumor tissue after intratumoral administration for several MHT cycles within three days. Thus, cobalt ferrite MNPs represent a perspective platform for tumor therapy by MHT due to their ability to provide effective heating without exerting a toxic effect on the organism. This opens up new avenues for smaller MNPs sizes while their heating efficiency is maintained