Behavioural responses of white and bronze turkeys (Meleagris gallopavo) to tonic immobility, gait score and open field tests in free-range system

WOS: 000438131200002This study was carried out to investigate the behavioural responses of white and bronze turkeys to tonic immobility (TI), gait score (GS) and open field (OF) tests in a free-range system. 144 female turkeys (72 white and 72 bronze) were studied for 23 weeks. They were 32 weeks old. The stocking density was 2 birds/m(2) indoors and 0.66 birds/m(2) outdoors. Both bird genotypes were fed on a diet containing 16% crude protein and 11.7 ME MJ/kg. The birds were weighed in the 32nd, 35th, 48th and 55th week. The turkeys' behaviour was determined by TI, GS and OF tests. Behavioural parameters were established for each applied test. Although the mortality rates of white and bronze turkeys during the study were 6% and 3%, respectively, the white turkeys showed better results in the TI and OF tests suggesting that are more native breed than bronze ones. The results indicate that bronze turkeys are more suited for use in free-range systems than white turkeys with respect to GS and the consequent mortality rates in latter ones.Scientific Research Projects Coordinatorship of Ahi Evran University in Turkey [AEU-PYO-ZRT.4001.12.016]This study was supported by the Scientific Research Projects Coordinatorship of Ahi Evran University in Turkey with AEU-PYO-ZRT.4001.12.016 project number

Effect of selection for body weight in Japanese quails (Coturnix coturnix Japonica) on some production traits

WOS: 000400881900030The aim of the study was to identify quails which have different body weight for some production traits such as egg production, egg characteristics, daily feed consumption and feed conversion ratio (FCR). The selection was based on body weight in Japanese quail over two generations using 150 quails (120 female and 30 male). These groups consisted of Low Body Weight (LBW), High Body Weight (HBW) and control. Average body weights for females at the end of five weeks were 182.3 +/- 0.5, 159.5 +/- 0.34, and 141.7 +/- 0.55 for LBW, HBW and control groups respectively. There were significant differences between females and males in body weight across the generations. Significant differences were observed for total egg production and egg width for Group X Generation's interactions. Also, statistically significant differences were found for egg quality parameters such as yolk index, yolk height; yolk diameter, albumin length, and albumin width among generations. As a result, body weight is a very important factor in selection studies and it also increases the efficiency of the selection program with other selection features

Volume status effected by gravity and body fluid shifts: new protocol for bioimpedance measurements

WOS: 000344391400019PubMed ID: 2523849

NATIVE RENAL BIOPSIES PERFORMED IN OLDER ADULTS ARE INCREASING: TWELVE YEARS EXPERIENCE OF EGE UNIVERSITY

WOS: 000298241300002Introduction: Determination of the frequency and prevalence of biopsy proven nephropathies in older adults and adults is important for epidemiological studies. Materials and Method: Predominant glomerulonephritis (GN) in native renal biopsies of adults and older adults (>= 65 years) were evaluated. Results: Among a total of 1702 renal biopsies (males 52%, ages 16-82, mean 40 +/- 15 years), 121 (7%) were performed in persons >= 65 years old. The mean age at the time of renal biopsy increased from 37.3 +/- 16.8 in 1996 to 44 +/- 16.1 years in 2009. The leading indications for biopsy in older and younger age groups were nephrotic syndrome (NS) (46.5% vs. 39.8% respectively), asymptomatic urinary abnormalities (20.9% vs. 33.4% respectively) acute renal failure (15.1% vs. 7.4% respectively) and hematuria (4.7% vs. 10.9% respectively). The etiologies of NS were amyloidosis, membranous GN and focal segmental glomerulosclerosis (FSGS) in both age groups. Primary GN was the predominant etiology in both age groups. Above 65 years, membranous (14.8%) and crescentic (9.9%) GNs were predominant while below 65 years IgA nephropathy (9%) was predominant. Among secondary GNs, amyloidosis (19%) and lupus nephritis (11.7%) were also predominant in the elderly and the younger persons respectively. Conclusion: The current data represents the experience of a single center. Such registries will allow epidemiologic studies to answer several open questions regarding both prevention and treatment of nephropathies in different age groups

A Case of Idiopathic Intracranial Hypertension Related with Vesicoureteral Reflux

Pseudotumor cerebri is idiopathic intracranial hypertension. The etiology of this syndrome has not been fully clarified. Excess cerebrospinal fluid production, scarcity of cerebrospinal fluid absorption, intracranial venous pressure elevation, increased intracranial blood volume are all thought to be responsible. The symptoms of the disease may be ordered according to prevalence as follows: headache due to increased intracranial pressure, blurred vision and diplopia. A thirteen-year-old female patient was brought in with complaints of headache, double and blurred vision. Systemic arterial hypertension (140/70 mmHg) was determined. Vesicoureteral reflux was detected as the hypertension etiology. In this article a rare pseudotumor cerebri case is presented secondary to vesicoureteral reflux which caused hypertension

THE EFFECTS OF COLCHICINE ON THE PROGRESSION AND REGRESSION OF ENCAPSULATING PERITONEAL SCLEROSIS

12th Congress of the International-Society-for-Peritoneal-Dialysis -- JUN 20-24, 2008 -- Istanbul, TURKEYWOS: 000262915200011PubMed ID: 19008543Background: Encapsulating peritoneal sclerosis (EPS) is an infrequent but extremely serious complication of long-term peritoneal dialysis. Fibrosis of the submesothelial compact zone and neoangiogenesis underlie the pathophysiology of EPS. Colchicine is a well-known anti-inflammatory and antifibrotic agent that has been used for some fibrosing clinical states, such as liver fibrosis. Objective: To determine the antifibrotic and anti-inflammatory effects of colchicine in an EPS rat model in both progression ( P) and regression ( R). Methods: 48 nonuremic albino Wistar rats were divided into 5 groups: control group, 2 mL isotonic saline intraperitoneally (IP) daily for 3 weeks; CG group, IP injection of 2 mL/200 g chlorhexidine gluconate ( CG) (0.1%) and ethanol (15%) dissolved in saline, daily for 3 weeks; resting group, CG (0 - 3 weeks) + peritoneal resting (4 - 6 weeks); C-R group, CG ( 0 - 3 weeks) + 1 mg/L colchicine ( 4 - 6 weeks); C-P group, CG ( 0 - 3 weeks) + 1 mg/L colchicine in drinking water ( 0 - 3 weeks). At the end, a 1-hour peritoneal equilibration test was performed with 25 mL 3.86% peritoneal dialysis solution. Dialysate-to-plasma ratio of urea (D/P urea), dialysate WBC count, ultrafiltration volume, and morphological changes of parietal peritoneum were examined. Result: Exposure to CG for 3 weeks resulted in alterations in peritoneal transport ( increased D/P urea, decreased ultrafiltration volume; p < 0.05) and morphology ( increased inflammation, neovascularization, fibrosis, and peritoneal thickness; p < 0.05). Resting had some beneficial effects on peritoneal derangements; however, once the peritoneum had been stimulated, resting alone was not enough to reverse these pathological changes. Colchicine had more pronounced effects on membrane integrity via decreased inflammation, cell infiltration, and vascularity compared to the resting group. Conclusion: We suggest that colchicine may have therapeutic value in the management of EPS.Int Soc Peritoneal Dialysi

Investigation of the genetic diversity and flea-borne pathogens in Ctenocephalides felis samples collected from goats in ?Izmir and S , anl?urfa provinces of Turkey

The cat flea Ctenocephalides felis has veterinary and medical importance since it is a vector for numerous important pathogens. In this study, a total of 249 flea samples were collected from goats bred in eight different farms (located in Izmir and S,anliurfa provinces of Turkey) and morphologically identified under microscopy. Later, the genetic diversity was investigated in 117 of C. felis samples that were morphologically identified by sequencing the mitochondrial cox1 gene, followed by phylogenetic tree, haplotype, genetic differentiation and gene flow analyses. In addition, Rickettsia spp. and Bartonella spp. which are zoonoses were screened in 27 pools comprising 249 flea samples by PCR. The phylogenetic tree showed that 117 flea samples were clustered in Clade 1 together with isolates from Australia, New Zealand, the Czech Republic, and India. Four haplotypes (haplo-types I, II, III and IV) were detected within the C. felis species. The most prevalent haplotype was haplotype I (57/ 117; 48.7 %). Among the population of flea samples in Izmir and S,anliurfa, the Fst and Nm values were 0.16261 and 2.57, respectively, indicating a moderate genetic differentiation and high gene flow. Rickettsia spp. was detected in four of C. felis pool samples whereas Bartonella spp. was detected in 25 of them. BLAST analysis identified R. raoultii as well as B. henselae and B. elizabethae. In conclusion, the findings showed that C. felis samples collected from goats in Turkey were classified within Clade 1 representing four different haplotypes with a moderate genetic diversity for the first time. Also, R. raoultii, B. henselae and B. elizabethae were demonstrated for the first time in cat flea samples collected in Turkey.Ege University Scientific Research Projects Coordination Unit; [TGA- 2019-20233]Funding This study was supported by a project given by the Ege University Scientific Research Projects Coordination Unit (Project number: TGA- 2019-20233) to H.C

Effects of ranibizumab and zoledronic acid on endometriosis in a rat model

Purpose To investigate the histological efficacy of ranibizumab and zoledronic acid in an experimentally induced endometriosis model as compared with danazol, buserelin acetate and dienogest. Methods Endometrial implants were introduced in 52 female Wistar albino rats, which were then randomly divided into six groups. The animals were, respectively, given dienogest, danazol, buserelin acetate, zoledronic acid, ranibizumab and 0.9% NaCl. After 4 weeks, the volumes and histopathological properties of the implants were evaluated and the implants were excised completely at the third laparotomy. A histopathological scoring system was used to evaluate the preservation of epithelia. Endometrial explants were evaluated immunohistochemically. Results Among the groups, the histological score was significantly lower in the zoledronic acid and ranibizumab groups compared with the controls (p 0.001). There were no significant differences regarding ellipsoidal volume levels between groups (p > 0.05). However, there was a statistically significant difference regarding cell numbers according to the degree of Bcl-2, NF-kappa B, and CD31 staining (p 0.001). There was no statistically significant difference in Bcl-2, CD31, or NF-kappa B staining in the binary comparisons between the other groups (p > 0.05). For Bcl-2 staining, the staining rate of the group treated with zoledronic acid was significantly lower compared with the dienogest and danazol groups (p 0.05). The staining rates of CD31 and NF-kappa B were significantly lower in the zoledronic acid and ranibizumab groups compared with the controls (p 0.05). Conclusion According to these results, zoledronic acid and ranibizumab may be putative candidates for the treatment of endometriosis.This study was funded by The Technological and Scientific Research Council of Turkey (TUBITAK) (213S002).Technological and Scientific Research Council of Turkey (TUBITAK) [213S002