A CROSS SECTIONAL STUDY TO EVALUATE ACUTE KIDNEY INJURY IN SCRUB TYPHUS PATIENTS: ACUTE KIDNEY INJURY IN SCRUB TYPHUS PATIENTS

OBJECTIVE: This study was conducted with the objective to estimate the incidence and severity of acute kidney injury [AKI] scrub typhus patients. METHODS: This was a cross-sectional study conducted 90 patients diagnosed with scrub typhus in a tertiary care centre. Basic demographic and treatment details of the patients were recorded. Routine haematological investigations and biochemical profiles were performed upon admission and follow-up.  AKI was defined and classified based on the RIFLE criteria RESULTS: Mean age of the patients was 49.0 ± 19.5 years and female preponderance was observed. The haemoglobin level was significantly lower in AKI patients as compared to non-AKI patients. Meanwhile, there was a significant increase in mean TLC count, CRP, Total bilirubin in AKI patients as compared to non-AKI patients.  was significantly higher  as compared to those without AKI . Increasing age, ICU admission, shock, urinary abnormalities and mechanical ventilation were the factors significantly associated with AKI. CONCLUSION AKI is a frequently reported complication in scrub typhus patients. In evaluating febrile illness associated with AKI, scrub typhus should be considered