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    Π―Π·Π²Ρ‹ ΠœΠ°Ρ€Ρ‚ΠΎΡ€Π΅Π»Π»Π°

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    There is description in the article of a case of hypertensive ulcer pathology of legs or Martorell’s ulcers diagnostics, which are complications of long-standing and poor-controlled essential hypertension. The patient 42 years old male presented with complaints of long-standing, non-healing and painful ulcer on the left leg, sustained blood pressure elevation (up to 230/120 mm Hg). History disease revealed blood pressure elevations since 16 years old age, but the patient sought medical advice extremely seldom and did not take antihypertensive treatment in fact. He noted when was 35 years old a painful ulcer located on anterolateral surface of the leg. Concerning it he treated by himself unsuccessfully and then β€” in differ ent health care centers. The condition deteriorated in 2016, when ulcer defect become larger and more painful. On admission at examination the ulcer of oval shape (size 7 Γ— 4 cm and depth 0.6 cm) on anterolateral surface of the lower third of left leg is present. In clinical and biochemistry analyses no pathology was found. There were signs of left ventricle hypertrophy on the data of electroand echocardiographic inves tigations. No alterations during complex ultrasound examination of vessels of both lower extremities were revealed. Examination of angiosurgeon: no pathology. With the purpose to diagnosis specification path omorphologic study of tissue fragments of injured zone was performed. The results of this study showed that revealed changes are relevant for hypertensive ulcers of legs or Martorell’s ulcers. The presented case illustrates the necessity of more broad informing medical community about possibility of incidence of Martorell’s ulcers that in turn assumes application of adequate measures of local treat ment, including dermatoplasty, and effective antihypertensive therapy.Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ приводится описаниС случая диагностики гипСртоничСских язв Π½ΠΈΠΆΠ½ΠΈΡ… конСчностСй, ΠΈΠ»ΠΈ язв ΠœΠ°Ρ€Ρ‚ΠΎΡ€Π΅Π»Π»Π° (ЯМ), ΡΠ²ΠΈΠ²ΡˆΠΈΡ…ΡΡ ослоТнСниСм Π΄Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠΉ ΠΈ ΠΏΠ»ΠΎΡ…ΠΎ ΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»ΠΈΡ€ΡƒΠ΅ΠΌΠΎΠΉ гипСртоничСской Π±ΠΎΠ»Π΅Π·Π½ΠΈ. ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½ больной 42 Π»Π΅Ρ‚ с ΠΆΠ°Π»ΠΎΠ±Π°ΠΌΠΈ Π½Π° Π΄Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎ Π½Π΅ Π·Π°ΠΆΠΈΠ²Π°ΡŽΡ‰ΡƒΡŽ, Π±ΠΎΠ»Π΅Π·Π½Π΅Π½Π½ΡƒΡŽ язву Π½Π° Π»Π΅Π²ΠΎΠΉ Π³ΠΎΠ»Π΅Π½ΠΈ, стойкоС ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½ΠΈΠ΅ Π°Ρ€Ρ‚Π΅Ρ€ΠΈΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ давлСния (Π΄ΠΎ 230/120 ΠΌΠΌ Ρ€Ρ‚. ст.). Из Π°Π½Π°ΠΌΠ½Π΅Π·Π° заболСвания извСстно, Ρ‡Ρ‚ΠΎ ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½ΠΈΠ΅ АД ΠΎΡ‚ΠΌΠ΅Ρ‡Π°Π΅Ρ‚ с 16-Π»Π΅Ρ‚Π½Π΅Π³ΠΎ возраста, ΠΎΠ΄Π½Π°ΠΊΠΎ Π·Π° мСдицинской ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ обращался ΠΊΡ€Π°ΠΉΠ½Π΅ Ρ€Π΅Π΄ΠΊΠΎ, Π°Π½Ρ‚ΠΈΠ³ΠΈΠΏΠ΅Ρ€Ρ‚Π΅Π½Π·ΠΈΠ²Π½ΡƒΡŽ Ρ‚Π΅Ρ€Π°ΠΏΠΈΡŽ фактичСски Π½Π΅ ΠΏΡ€ΠΈΠ½ΠΈΠΌΠ°Π». Π’ возрастС 35 Π»Π΅Ρ‚ ΠΎΠ±Π½Π°Ρ€ΡƒΠΆΠΈΠ» Π±ΠΎΠ»Π΅Π·Π½Π΅Π½Π½ΡƒΡŽ язву Π½Π° Π½ΠΈΠΆΠ½Π΅ΠΉ Ρ‚Ρ€Π΅Ρ‚ΠΈ ΠΏΠ΅Ρ€Π΅Π΄Π½Π΅Π»Π°Ρ‚Π΅Ρ€Π°Π»ΡŒΠ½ΠΎΠΉ повСрхности Π³ΠΎΠ»Π΅Π½ΠΈ, ΠΊΠΎΡ‚ΠΎΡ€ΡƒΡŽ Π±Π΅Π·ΡƒΡΠΏΠ΅ΡˆΠ½ΠΎ Π»Π΅Ρ‡ΠΈΠ» ΡΠ°ΠΌΠΎΡΡ‚ΠΎΡΡ‚Π΅Π»ΡŒΠ½ΠΎ, Π° Π΄Π°Π»Π΅Π΅ β€” Π² Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Ρ… Π»Π΅Ρ‡Π΅Π±Π½Ρ‹Ρ… учрСТдСниях. БостояниС ΡƒΡ…ΡƒΠ΄ΡˆΠΈΠ»ΠΎΡΡŒ Π² 2016 Π³., ΠΊΠΎΠ³Π΄Π° язвСнный Π΄Π΅Ρ„Π΅ΠΊΡ‚ увСличился Π² Ρ€Π°Π·ΠΌΠ΅Ρ€Π°Ρ…, стал Ρ€Π΅Π·ΠΊΠΎ Π±ΠΎΠ»Π΅Π·Π½Π΅Π½Π½Ρ‹ΠΌ. ΠŸΡ€ΠΈ осмотрС Π² ΠΌΠΎΠΌΠ΅Π½Ρ‚ поступлСния Π² ΠΊΠ»ΠΈΠ½ΠΈΠΊΡƒ отмСчаСтся язва овальной Ρ„ΠΎΡ€ΠΌΡ‹ Ρ€Π°Π·ΠΌΠ΅Ρ€ΠΎΠΌ 7 Γ— 4 см ΠΈ Π³Π»ΡƒΠ±ΠΈΠ½ΠΎΠΉ 0,6 см Π½Π° ΠΏΠ΅Ρ€Π΅Π΄Π½Π΅Π»Π°Ρ‚Π΅Ρ€Π°Π»ΡŒΠ½ΠΎΠΉ повСрхности Π½ΠΈΠΆΠ½Π΅ΠΉ Ρ‚Ρ€Π΅Ρ‚ΠΈ Π»Π΅Π²ΠΎΠΉ Π³ΠΎΠ»Π΅Π½ΠΈ. Π’ клиничСских ΠΈ биохимичСских Π°Π½Π°Π»ΠΈΠ·Π°Ρ… ΠΊΡ€ΠΎΠ²ΠΈ ΠΈ ΠΌΠΎΡ‡ΠΈ β€” Π±Π΅Π· ΠΏΠ°Ρ‚ΠΎΠ»ΠΎΠ³ΠΈΠΈ. На элСктрои эхокардиограммС β€” ΠΏΡ€ΠΈΠ·Π½Π°ΠΊΠΈ Π³ΠΈΠΏΠ΅Ρ€Ρ‚Ρ€ΠΎΡ„ΠΈΠΈ Π»Π΅Π²ΠΎΠ³ΠΎ ΠΆΠ΅Π»ΡƒΠ΄ΠΎΡ‡ΠΊΠ°. ΠŸΡ€ΠΈ комплСксном ΡƒΠ»ΡŒΡ‚Ρ€Π°Π·Π²ΡƒΠΊΠΎΠ²ΠΎΠΌ исслСдовании сосудов Π½ΠΈΠΆΠ½ΠΈΡ… конСчностСй ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ Π½Π΅ выявлСно. ΠžΡΠΌΠΎΡ‚Ρ€ Π°Π½Π³ΠΈΠΎΡ…ΠΈΡ€ΡƒΡ€Π³Π°: Π±Π΅Π· ΠΏΠ°Ρ‚ΠΎΠ»ΠΎΠ³ΠΈΠΈ. Для уточнСния Π΄ΠΈΠ°Π³Π½ΠΎΠ·Π° Π±Ρ‹Π»ΠΎ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΎ морфологичСскоС исслСдованиС Ρ‚ΠΊΠ°Π½Π΅Π²Ρ‹Ρ… Ρ„Ρ€Π°Π³ΠΌΠ΅Π½Ρ‚ΠΎΠ² Ρ€Π°Π½Π΅Π²ΠΎΠΉ Π·ΠΎΠ½Ρ‹, Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΊΠΎΡ‚ΠΎΡ€ΠΎΠ³ΠΎ ΡΠ²ΠΈΠ΄Π΅Ρ‚Π΅Π»ΡŒΡΡ‚Π²ΠΎΠ²Π°Π»ΠΈ ΠΎΠ± измСнСниях, Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€Π½Ρ‹Ρ… для гипСртоничСских язв Π½ΠΈΠΆΠ½ΠΈΡ… конСчностСй ΠΈΠ»ΠΈ ЯМ. ΠŸΡ€ΠΈΠ²Π΅Π΄Π΅Π½Π½Ρ‹ΠΉ случай ΠΈΠ»Π»ΡŽΡΡ‚Ρ€ΠΈΡ€ΡƒΠ΅Ρ‚ Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎΡΡ‚ΡŒ ΡˆΠΈΡ€ΠΎΠΊΠΎΠ³ΠΎ информирования мСдицинской общСствСнности ΠΎ вСроятности встрСчаСмости ЯМ, Ρ‡Ρ‚ΠΎ, Π² свою ΠΎΡ‡Π΅Ρ€Π΅Π΄ΡŒ, ΠΏΡ€Π΅Π΄ΠΏΠΎΠ»Π°Π³Π°Π΅Ρ‚ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ Π°Π΄Π΅ΠΊΠ²Π°Ρ‚Π½Ρ‹Ρ… ΠΌΠ΅Ρ€ мСстной Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ, Π²ΠΊΠ»ΡŽΡ‡Π°Ρ дСрматопластику, ΠΈ эффСктивной Π°Π½Ρ‚ΠΈΠ³ΠΈΠΏΠ΅Ρ€Ρ‚Π΅Π½Π·ΠΈΠ²Π½ΠΎΠΉ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ

    ΠžΡΡ‚Ρ€Ρ‹ΠΉ Π°Ρ€Ρ‚Ρ€ΠΈΡ‚, ассоциированный с COVID-19

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    Coronavirus infection (COVID-19) is usually characterized by respiratory symptoms, but can have a wide range of clinical manifestations. The growing interest is focusing on the short-term and long-term immune-mediated sequelae triggered by the COVID-19. One of these complications is post-infectious arthritis, classified by some authors as reactive. This paper summarizes and analyzes 25 clinical cases of COVID-19-associated acute arthritis that have been published from January 2020 to November 2021. The mean age of the patients was 46 14 years, with the disease being more prevalent in men than in women. Joint lesions were mono- or polyarticular, with predominant involvement of the joints of the lower extremities. HLA-B27 antigen was determined in 13 of 25 patients and was found in 30% of cases. Like many other viral diseases, the severe acute respiratory syndrome 2 caused by coronavirus can act as a causative agent or a trigger in the development of inflammatory arthritis in predisposed individuals. The post-infectious arthritis should be differentiated from diseases that can manifest with a similar clinical presentation, which requires a complex of laboratory and instrumental studies. Non-steroidal anti-inflammatory drugs and glucocorticosteroids are successfully used in the treatment. The number of cases of post-COVID-19-arthritis is increasing, which urges further studies of its pathophysiology, diagnosis and treatment regimens.ΠšΠΎΡ€ΠΎΠ½Π°Π²ΠΈΡ€ΡƒΡΠ½Π°Ρ инфСкция (COVID-19) ΠΎΠ±Ρ‹Ρ‡Π½ΠΎ характСризуСтся рСспираторными симптомами, ΠΎΠ΄Π½Π°ΠΊΠΎ ΠΌΠΎΠΆΠ΅Ρ‚ ΠΈΠΌΠ΅Ρ‚ΡŒ ΡˆΠΈΡ€ΠΎΠΊΠΈΠΉ спСктр клиничСских проявлСний. Растущий интСрСс Π²Ρ‹Π·Ρ‹Π²Π°ΡŽΡ‚ краткосрочныС ΠΈ долгосрочныС иммуноопосрСдованныС послСдствия, Π²Ρ‹Π·Π²Π°Π½Π½Ρ‹Π΅ COVID-19. Одно ΠΈΠ· Ρ‚Π°ΠΊΠΈΡ… ослоТнСний постинфСкционный Π°Ρ€Ρ‚Ρ€ΠΈΡ‚, классифицируСмый Π½Π΅ΠΊΠΎΡ‚ΠΎΡ€Ρ‹ΠΌΠΈ Π°Π²Ρ‚ΠΎΡ€Π°ΠΌΠΈ ΠΊΠ°ΠΊ Ρ€Π΅Π°ΠΊΡ‚ΠΈΠ²Π½Ρ‹ΠΉ. Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ ΠΎΠ±ΠΎΠ±Ρ‰Π΅Π½Ρ‹ ΠΈ ΠΏΡ€ΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Π½Ρ‹ ΠΎΠΏΡƒΠ±Π»ΠΈΠΊΠΎΠ²Π°Π½Π½Ρ‹Π΅ Π² Π»ΠΈΡ‚Π΅Ρ€Π°Ρ‚ΡƒΡ€Π΅ с января 2020 ΠΏΠΎ Π½ΠΎΡΠ±Ρ€ΡŒ 2021 Π³ΠΎΠ΄Π° 25 клиничСских наблюдСний острого Π°Ρ€Ρ‚Ρ€ΠΈΡ‚Π°, ассоциированного с COVID-19. Π‘Ρ€Π΅Π΄Π½ΠΈΠΉ возраст ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² составил 46 14 Π»Π΅Ρ‚, ΠΏΡ€ΠΈ этом ΠΌΡƒΠΆΡ‡ΠΈΠ½Ρ‹ Π±ΠΎΠ»Π΅Π»ΠΈ Ρ‡Π°Ρ‰Π΅, Ρ‡Π΅ΠΌ ΠΆΠ΅Π½Ρ‰ΠΈΠ½Ρ‹. ΠŸΠΎΡ€Π°ΠΆΠ΅Π½ΠΈΠ΅ суставов Π±Ρ‹Π»ΠΎ ΠΌΠΎΠ½ΠΎ- ΠΈΠ»ΠΈ полиартикулярным, с прСимущСствСнным Π²ΠΎΠ²Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅ΠΌ суставов Π½ΠΈΠΆΠ½ΠΈΡ… конСчностСй. ΠžΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ Π°Π½Ρ‚ΠΈΠ³Π΅Π½Π° HLA-B27 Π²Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ΠΎ Ρƒ 13 ΠΈΠ· 25 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² ΠΈ Π² 30% случаСв ΠΏΠΎΠΊΠ°Π·Π°Π»ΠΎ ΠΏΠΎΠ»ΠΎΠΆΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹ΠΉ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚. Как ΠΈ ΠΌΠ½ΠΎΠ³ΠΈΠ΅ Π΄Ρ€ΡƒΠ³ΠΈΠ΅ вирусныС заболСвания, коронавирус тяТСлого острого рСспираторного синдрома 2 ΠΌΠΎΠΆΠ΅Ρ‚ Π²Ρ‹ΡΡ‚ΡƒΠΏΠ°Ρ‚ΡŒ Π² качСствС возбудитСля ΠΈΠ»ΠΈ Ρ‚Ρ€ΠΈΠ³Π³Π΅Ρ€Π° развития Π²ΠΎΡΠΏΠ°Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ Π°Ρ€Ρ‚Ρ€ΠΈΡ‚Π° Ρƒ прСдрасполоТСнных людСй. Π‘Π»Π΅Π΄ΡƒΠ΅Ρ‚ ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΡ‚ΡŒ Π΄ΠΈΡ„Ρ„Π΅Ρ€Π΅Π½Ρ†ΠΈΠ°Π»ΡŒΠ½ΡƒΡŽ диагностику постинфСкционного Π°Ρ€Ρ‚Ρ€ΠΈΡ‚Π° с заболСваниями, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ ΠΌΠΎΠ³ΡƒΡ‚ ΠΏΡ€ΠΎΡΠ²Π»ΡΡ‚ΡŒΡΡ схоТСй клиничСской ΠΊΠ°Ρ€Ρ‚ΠΈΠ½ΠΎΠΉ, для Ρ‡Π΅Π³ΠΎ Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎ Π²Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ΠΈΠ΅ комплСкса Π»Π°Π±ΠΎΡ€Π°Ρ‚ΠΎΡ€Π½Ρ‹Ρ… ΠΈ ΠΈΠ½ΡΡ‚Ρ€ΡƒΠΌΠ΅Π½Ρ‚Π°Π»ΡŒΠ½Ρ‹Ρ… исслСдований. Для лСчСния ΡƒΡΠΏΠ΅ΡˆΠ½ΠΎ ΠΈΡΠΏΠΎΠ»ΡŒΠ·ΡƒΡŽΡ‚ΡΡ нСстСроидныС ΠΏΡ€ΠΎΡ‚ΠΈΠ²ΠΎΠ²ΠΎΡΠΏΠ°Π»ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Π΅ ΠΏΡ€Π΅ΠΏΠ°Ρ€Π°Ρ‚Ρ‹ ΠΈ Π³Π»ΡŽΠΊΠΎΠΊΠΎΡ€Ρ‚ΠΈΠΊΠΎΡΡ‚Π΅Ρ€ΠΎΠΈΠ΄Ρ‹. Число случаСв постковидного Π°Ρ€Ρ‚Ρ€ΠΈΡ‚Π° растСт, Ρ‡Ρ‚ΠΎ Π΄Π΅Π»Π°Π΅Ρ‚ Π°ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½Ρ‹ΠΌ дальнСйшСС ΠΈΠ·ΡƒΡ‡Π΅Π½ΠΈΠ΅ ΠΏΠ°Ρ‚ΠΎΠ³Π΅Π½Π΅Π·Π°, диагностики ΠΈ схСм лСчСния этого заболСвания

    Overview of American Heart Association / American College of Cardiology guidelines 2017 for management of patients with valvular heart disease

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    n June 2017, Circulation journal published updated recommendations of the American Heart Association and the American College of Cardiology (AHA / ACC) on the management of patients with valvular heart disease. The main provisions of this manual are set out in this message. It should be emphasized that the recommendations written by leading US experts in this field are set out clearly, using a variety of tables and figures, which will undoubtedly make them a desktop guide to action for most practitioners in the following years. As usual, when creating such guidelines, the authors were guided by evidence-based methodology using the classes of recommendations and levels of evidence

    Myocardial damage in cardioplegia and cardiopulmonary bypass

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    Cardiopulmonary bypass and cardioplegia are the most frequently used techniques in cardiac surgery. The level of cardiac mortality in the postoperative period depends on them both directly and indirectly. A review of recent data on the pathogenetic mechanisms of myocardial damage in cardioplegia and cardiopulmonary bypass, methods of its diagnosis and basic strategies of myocardial protection is provided
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