79 research outputs found

    How daily supervisor abuse and coworker support affect daily work engagement

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    The purpose of this study was to explore the dynamic and intervention mechanisms of daily abusive experience affecting daily work engagement. Drawing on conservation of resources (COR) theory, we examine the effect of daily abusive supervision on daily work engagement through daily negative emotions from the resource consumption perspective, and the moderation effect of coworker support from the resource provision perspective. Using a daily diary approach and based on a sample of 73 employees for 5 consecutive days in China. The results reveal that daily abusive supervision has a significant negative effect on daily work engagement, daily negative emotions mediate this relationship, and coworker support had a cross-level moderating effect between daily abusive supervision and daily negative emotions. Our study shows ways to boost employees’ daily work engagement and especially ways buffer the negative effect of abused experience on work engagement

    Corrosion Analysis and Corresponding Countermeasures of Steel Structures in Offshore Wind Farms

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    [Introduction] Strategies for preventing corrosion in steel structures at offshore wind farms, derived from a comprehensive study on the environmental conditions, symptoms, and mechanisms of corrosion in such structures, as well as an analysis on various causes were proposed, aiming to ensure safe operation throughout their lifecycle. [Method] The study focused on the grid-connected offshore wind farms and investigated corrosion observed in specific marine environmental conditions for different foundation types, structural components, materials, and parts. [Result] The results show that corrosion appears in various forms and progresses at varying rates among different foundation types, structural components, and parts in specific marine environmental conditions. Electrochemical corrosion is identified as the main form of corrosion, while internal and external stresses act as potential accelerators of corrosion in steel structures. Manufacturing quality control and the implementation of protective measures directly affect the rate of corrosion development.[Conclusion] In summary, it is crucial to identify various potential risks related to manufacturing characteristics, material properties, and environmental conditions of steel structures at offshore wind farms and take appropriate refined protection measures to eliminate underlying causes. In addition, protection levels should be increased for certain critical parts

    Analytical modeling of gas production rate in tight channel sand formation and optimization of artificial fracture

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    Permeability variation in tight channel sand formation makes an important role in gas production. Based on the features of channel sand formation, a mathematical model has been established considering anisotropy of permeability. The analytical solutions were derived for productivity of both vertical wells and vertically fractured wells. Simulation results show that, gas production rate of anisotropic channel sand formation is less than that of isotropic formation. For vertically fractured well, artificial fracture direction, drainage radius, permeability ratio and fracture half-length have considerable influence on production rate. The optimum fracture direction should be deviated less than π/8 from the maximum permeability direction (or the channel direction). In addition, the analytical model was verified by in situ measured data. The research provides theoretical basis for the development of tight channel sand gas reservoirs

    Magnetic Resonance Imaging of Bone Marrow Cell-Mediated Interleukin-10 Gene Therapy of Atherosclerosis

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    A characteristic feature of atherosclerosis is its diffuse involvement of arteries across the entire human body. Bone marrow cells (BMC) can be simultaneously transferred with therapeutic genes and magnetic resonance (MR) contrast agents prior to their transplantation. Via systemic transplantation, these dual-transferred BMCs can circulate through the entire body and thus function as vehicles to carry genes/contrast agents to multiple atherosclerosis. This study was to evaluate the feasibility of using in vivo MR imaging (MRI) to monitor BMC-mediated interleukin-10 (IL-10) gene therapy of atherosclerosis.For in vitro confirmation, donor mouse BMCs were transduced by IL-10/lentivirus, and then labeled with a T2-MR contrast agent (Feridex). For in vivo validation, atherosclerotic apoE(-/-) mice were intravenously transplanted with IL-10/Feridex-BMCs (Group I, n = 5) and Feridex-BMCs (Group II, n = 5), compared to controls without BMC transplantation (Group III, n = 5). The cell migration to aortic atherosclerotic lesions was monitored in vivo using 3.0T MRI with subsequent histology correlation. To evaluate the therapeutic effect of BMC-mediated IL-10 gene therapy, we statistically compared the normalized wall indexes (NWI) of ascending aortas amongst different mouse groups with various treatments.Of in vitro experiments, simultaneous IL-10 transduction and Feridex labeling of BMCs were successfully achieved, with high cell viability and cell labeling efficiency, as well as IL-10 expression efficiency (≥90%). Of in vivo experiments, MRI of animal groups I and II showed signal voids within the aortic walls due to Feridex-created artifacts from the migrated BMCs in the atherosclerotic plaques, which were confirmed by histology. Histological quantification showed that the mean NWI of group I was significantly lower than those of group II and group III (P<0.05).This study has confirmed the possibility of using MRI to track, in vivo, IL-10/Feridex-BMCs recruited to atherosclerotic lesions, where IL-10 genes function to prevent the progression of atherosclerosis

    Ab Initio Molecular Dynamics Study of the Structure and Properties of Nb-Doped Zr-Cu-Al Amorphous Alloys

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    In this paper, experiments were carried out on (Zr0.5Cu0.4Al0.1)100-xNbx (x = 0, 3, 6 at.%) amorphous alloys, and the corresponding ab initio molecular dynamics simulation was performed. The results showed that stable structures of Nb-centered and Al-centered icosahedral (-like) atomic clusters were formed after a small amount of (3 at.%) Nb was added. Stable and close-packed backbone structures were formed by the means of interconnection and matching of the two kinds of stable clusters in the alloys, which also enhanced the overall heterogeneity of the structures, thereby improving the strength and macroscopic plasticity. In addition, when more (6 at.%) Nb was added, the stable Al-centered clusters were replaced by some stable Nb-centered clusters in the alloys, and the stability and heterogeneity of the structures were partly reduced, which reduced the strength and macroscopic plasticity
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