Self, the Ultimate and “others” in pre-Qin conceptions of sagehood

This study is an analysis of sagehood in pre-Qin Confucianism from the perspective of the relations between the self, the Ultimate and “others”. By examining the etymological, textual and philosophical evolutions on the concept of sheng (聖) in pre-Qin Chinese tradition, I argue that the pre-Qin Confucians developed a dual system of the Ultimate and hence a dual process of sagehood cultivation. The pre-Qin Confucians since Confucius inherited the ancient idea of the transcendent Ultimate in the names of Di (帝) and Tian (天) with the transcendent Ultimate, the ancient sage-kings, the people and the Rituals as the authorities. Meanwhile, they developed ideas regarding the immanent Ultimate that linked it to Nature (Xing 性), as well as specific corresponding ideas about the self, including Nature, mind/heart (xin 心) and body (shen 身) rooted in the early Zhou dynasty. The ideas about Nature, mind/hear and body broke or redefined the self-other boundaries between the self, the Ultimate and “others”. This new perspective made it possible and feasible for the self to know and become one with “others” intellectually, emotionally and empathetically in accordance with the Way of the Ultimate. Thus, the pre-Qin cultivation of sagehood became a two-fold process. On the one hand, the self willingly chooses to be subjected to, and even internalize, the authoritative “others”, such as the transcendent Ultimate, the sages and the Rituals. On the other hand, the self willingly chooses to be subordinate to the immanent Ultimate via his/her own Nature, mind/heart and body, and to grow from within and enlarge itself from the basic unit shen until becoming one with the Ultimate vertically and all others horizontally in accordance with the Way of the Ultimate. This two-sided process is conducted simultaneously, interactively and ceaselessly as different aspects of the same process. In this process “shen" is located at the center, being self-consciously transformed by the Ultimate, while also transforming “others” from near to far

Effects of antipsychotics on bone mineral density and prolactin levels in patients with schizophrenia: a 12-month prospective study

Objective: Effects of conventional and atypical antipsychotics on bone mineral density (BMD) and serum prolactin levels (PRL) were examined in patients with schizophrenia.Methods: One hundred and sixty-three first-episode inpatients with schizophrenia were recruited, to whom one of three conventional antipsychotics (perphenazine, sulpiride, and chlorpromazine) or one of three atypical antipsychotics (clozapine, quetiapine, and aripiprazole)was prescribed for 12 months as appropriate. BMD and PRL were tested before and after treatment. Same measures were conducted in 90 matched healthy controls.Results Baseline BMD of postero-anterior L1–L4 range from 1.04 ± 0.17 to 1.42 ± 1.23, and there was no significant difference between the patients group and healthy control group. However, post-treatment BMD values in patients (ranging from 1.02 ± 0.15 to 1.23 ± 0.10) were significantly lower than that in healthy controls (ranging from 1.15 ± 0.12 to 1.42 ± 1.36). The BMD values after conventional antipsychotics were significantly lower than that after atypical antipsychotics. The PRL level after conventional antipsychotics (53.05 ± 30.25 ng/ml) was significantly higher than that after atypical antipsychotics (32.81 ± 17.42 ng/ml). Conditioned relevance analysis revealed significant negative correlations between the PRL level and the BMD values after conventional antipsychotics.Conclusion The increase of PRL might be an important risk factor leading to a high prevalence of osteoporosis in patients with schizophrenia on long-term conventional antipsychotic medication.<br/