Divergent synthesis of (+)-tanikolide and its analogues employing stereoselective rhodium(II)-catalyzed reaction

In this study, we described the divergent synthesis of (+)-tanikolide and its analogues, such as (4S)- and (4R)-hydroxytanikolides, and nortanikolide, employing a stereoselective dirhodium(II)-catalyzed reaction to construct the quaternary chiral center of tanokolides. The key steps involve (a) a dirhodium(II)-catalyzed oxonium ylide formation–[2,3]-sigmatropic rearrangement, (b) an N-heterocyclic carbene-catalyzed ring-expansion lactonization of tetrahydrofurfural, or (c) an oxidative cleavage of tetrahydrofuran-5-methanol to γ-lactone using a 2-iodobenzamide catalyst. This route would provide high flexibility for analogue synthesis because the long side chain can be introduced at a later stage in the synthesis

Examination of \u22MOKUMOKU Group\u22 group psychotherapy for children with developmental disabilities : Study of prognosis for group participants

本研究では，過去に集団心理療法活動に参加していた対象児・者に対して追跡調査を行い，現在の友人関係と社会的スキル・適応状況・精神的な健康度・保護者による子どもの社会的能力及び問題行動との関連を検討した。その結果友人関係認識尺度とEDIとの関連において友人関係認識高群が友人関係認識低群に対し得点が有意に高いこと友人関係認識尺度とKISSとの関連において友人関係認識高群が友人関係認識低群に対し得点が有意に低いこと，友人関係認識尺度とCBCLとの関連において「思考の問題」において友人関係認識高群が友人関係認識低群に対し得点が有意に高いことが示された。そのため，グループの中でいったんは友人関係に対し，ポジテイブな印象をもったとしても，その後友人関係に関しネガテイブな印象をもった場合精神的健康度は低くなる。今後は，卒業後に関しても友人関係に関し難しさを感じた場合に対応できるグループ設置の必要が示唆された。In this study, we conducted a follow-up study of children and adults to an object that has been participating in the activity group psychotherapy. Then, we examined the relationship between social competence and behavior problems of children by parents and mental health status, degree of adaptation skills and social relationships with friends today. As a result, the high group recognition friendship is significantly higher score was shown for the low group recognition in the context of relationships with friends and BDI perceived scale relationships with friends. In addition, the high group recognition friendship has been shown that for low group scored significantly lower in relation to the recognition friendship KISS perceived scale and relationships with friends. Furthermore, a high group recognizes that relationships with friends scored significantly higher for the low group was shown torecognize relationships with friends in the \u22problem of thinking.\u22 They have a positive impression for the friend relationship by the group. However, mental health become low if they have a negative impression regarding relationships with friends afterwards. Therefore, when they feel difficult relationships with friends, there is a need to set up the group to be able to respond

Children and Child-Rearing Support Needs in Western Kyushu:Focusing on the Results of an Interview Survey with Children Support Organization Staff

本研究では、九州西部地域における子どもの生活全般を見通した子ども・子育て支援ニーズを明らかにすることを目的とした。そのため、地域の子ども支援団体の支援者３名に対してインタビュー調査を行った。調査結果を質的に分析し、社会や地域の問題（制度やサービスの在り方）、子どもと親のニーズの２つの大項目が形成された。社会や地域の問題は、【子育ての中で感じる社会の不利益】【子ども支援における制度・公的サービスの不足】【地域の特性】【子どもとその家庭の地域とのつながり】【子育てにおける行政とのつながり】【学校の役割と課題】【子どもの教育のあり方】の７カテゴリーに、子どもと親のニーズは、【子どもを取り巻く環境】【親子の葛藤】【家での食事課題】【親の子育てにおける困難感】【支援を必要とする子ども】【子どもの生活習慣の見直し】【大人の子どもに対する理解】の７カテゴリーに分類された。今後、これらの子ども・子育て支援ニーズに対応をしていく必要がある。The purpose of this study was to clarify children and child-rearing support needs in Western Kyushu in view of children\u27s overall life.　To achieve this, interviews were conducted with three staff members from local children support organizations.In a qualitative analysis of survey results, the two main categories of Social and Community Issues（ Systems and Services ）and Children’s and Parents Needs were formed.　Social and　Community Issues were divided into the following seven categories: social disadvantages felt due to childrearing, lack of public services in children’s support, community characteristics, linkage between children and their families and the community, linkage with public services during parenting, role of and issues with schools, and children’s education.　Children’s and Parents’ Needs were divided into the following seven categories: children’s environment, children-parents conflict, food issues at home, difficulties felt in parenting, children in need of special support, improvement of children’s lifestyles, and adults’ understanding towards children.In the future, it will be necessary to respond to these children and child-rearing support needs

A Study on a Group \u22Mokumoku\u22 group psychotherapy for children with developmental disabilities : Longitudinal study of cognitive features and behavioral characteristics of children by WISCIII and CBCL

本研究では，集団心理療法「もくもくグループ」における臨床的意義と課題を検討するために，グループに継続して参加した児童・生徒の行動特徴・認知的特徴の発達について， CBCL・WISC Eを用い縦断的検討を行った。3年間のCBCLの縦断的検討を行った結果，初年度に境界域を超えていた項目において，有意に得点の減少が見られた。また， WISCEにおいては動作性IQ，全検査IQ，知覚統合の有意な上昇が見られた。もくもくグループの中でねらいとした，①他者に受け入れられる体験や，②自分の気持ちを他者と共有したり，他者の気持ちを聞いて自分の気持ちと折り合いをつけるなど円滑な相互交流をする体験，③セラピストの状況理解の促しといったものの影響が示唆された。The purpose of this paper was to examine the role of group psychotherapy \u22Mokumoku\u22 with the growth of behavioral and cognition characteristics of the students who participated continuously in the group, by using a longitudinal study with the WISCIII and CBCL. As a result of a longitudinal study of the CBCL for three years, in items beyond the boundary in the first year, there was a significant decrease in the score. In addition, As a result of the WISCIII are indicating that have significantly increased FIQ, FIQ, PO. From these results, the influence of the following three points are suggested. The first point is the experience that is acceptable to others. Second, it\u27s come to terms with the feelings and to share their feelings with others. The third point is that the therapist is for members to encourage understanding of the situation

The application of Dohsa-hou to the mothers who have the child with physically handicapped

要約 Ⅰ.問題 Ⅱ.本研究の目的 Ⅲ.活動の概要 Ⅳ.事例経過 Ⅴ.考察 Ⅵ.今後の課題 引用文献本稿では，肢体不自由の子どもを持つ親の会のメンバーからの相談に基づいた健康動作法の実践（生涯発達支援部門）について報告し同時にその意義を考えることを目的とする。来談者は、肢体不自由の子どもを持つ保護者（母親） 9名である。参加者は主として成人した肢体不自由の子どもを持ち， 日常生活における介護，家事，仕事の疲労などから身体の痛みや硬さなどの訴えが主なもので、あった。来談者は，動作法については子どもへの実践によってリラクセイション効果なとさについては知っているため動作法を受ける ことを希望しそれに基づいて月約2回の割合で3年間継続した。その健康動作法の実施の結果，身体的な不具合と身体・生活の不安の軽減などが本稿では，肢体不自由の子どもを持つ親の会のメンバーからの相談に基づいた健康動作法の実践（生涯発達支援部門）について報告し同時にその意義を考えることを目的とする。来談者は、肢体不自由の子どもを持つ保護者（母親） 9名である。参加者は主として成人した肢体不自由の子どもを持ち， 日常生活における介護，家事，仕事の疲労などから身体の痛みや硬さなどの訴えが主なもので、あった。来談者は，動作法については子どもへの実践によってリラクセイション効果などついては知っているため動作法を受けることを希望しそれに基づいて月約2回の割合で3年間継続した。その健康動作法の実施の結果，身体的な不具合と身体・生活の不安の軽減などが実感され，日常生活において肢体不自由を持つ子どもに対しての介助や世話にもゆとりが感じられるようになったなどの感想が述べられるようになった。これらのことから健康動作法を実施することは，肢体不自由の子どもを持つ親の日常を支えることにつながることが示唆された。The purpose of this study is to discuss the effects of Dohsa-hou to the mothers who had the son or daughter with physically handicapped causing cerebral palsy. Their child became to be adult who had continued to undergo Dohsa-hou therapy. They, however, had stiffness at any parts of body and they needed supports from the parents in daily life. The parents, especially mothers were hard to take care of their child, so they felt tired and had stiffness at their body like as the son and daughter. They knew very well the effect of Dohsa-hou, because they had own experience of Dousa-hou practice to their child. So, they applied the Dousa-hou to the Center, Kyushu University. They had been taken Dohsa-hou therapy twice a month for 3 years. Each session is 1 hour. The results of the therapy were the following. The clients described and reported that their stiffness and pain ant the body has been weakened and their anxiety of body or the behaviors of daily life have been reduced. And then, they reported that they felt easy and relaxed to take care of the child in daily life. These clients reports and descriptions suggest that Dohsa-hou could be effective as the support method for the parents who should be take care of their child with physically handicapped