Comparison of three methods of inhaling salbutamol in acute childhood asthma

Inhalation therapy with salbutamol sulphate was administered to 36 patients with acute asthma. The effect of salbutamol inhaled by three different methods were compared in three groups each consisting of 12 children. These methods were metered dose inhaler (MDI) with or without spacer and compressed nebuliser respectively. All patients were standardized by respiratory score. Respiratory score, peak expiratory flow rate (PEFR) with a wright peak flow meter, respiration rate, heart rate and blood pressures were measured before and during the six hours after inhalation therapy. These methods of inhalation therapy were satisfactory at the end of 6 hours. Treatment of acute asthma using a nebuliser was found to be significantly more successful compared to other methods (p < 0.01). Complications were not seen in any of the inhalation techniques

Inhalation therapy with magnesium sulfate and salbutamol sulfate in bronchial asthma

WOS: A1996UP29600006PubMed ID: 8701480Inhalation therapy with magnesium sulfate and salbutamol sulfate was applied to two groups, each consisting of 20 patients with acute asthma. The effects of inhaled magnesium sulfate and salbutamol sulfate were compared. The evaluation of patients was done using respiratory score, peak expiratory flow rate with a Wright peak flow meter, respiration rate, heart rate and blood pressure. Although magnesium-sulfate's bronchodilating effect continued for approximately one hour, treatment of acute asthma using salbutamol sulfate inhalation was found to be more successful and its effect continued for six hours

Sublingual immunotherapy and influence on urinary leukotrienes in seasonal pediatric allergy

WOS: 000083784100005PubMed ID: 10582199Sublingual immunotherapy has been suggested for the treatment of respiratory allergies, Many controversial studies have been reported on the efficacy of sublingual immunotherapy The aim of this prospective study was to evaluate whether sublingual immunotherapy was effective according to clinical and laboratory results in pediatric allergies. Thirty-nine allergic, grass pollen sensitive children were admitted into the study. Sublingual immunotherapy was given over a 12-month period to 21 children (mean age 10.5 +/- 3.3 years), 10 of whom had seasonal allergic rhinitis and II seasonal allergic asthma. During the same period, 18 children (mean age II. I +/- 2.5 years), 10 with seasonal allergic rhinitis and eight with seasonal allergic asthma, received placebo. Symptom scores and drug requirements were recorded and urine samples were collected to detect urinary levels of leukotrienes (Uc-LTB4 and Uc-LTE4). In patients who received sublingual immunotherapy, the symptom scores of seasonal allergic rhinitis significantly decreased but no statistically significant changes were observed in terms of symptoms of seasonal allergic asthma. Uc-LTE4 and Uc-LTB4 levels of seasonal allergic rhinitis, with a geometric mean and 95% confidence interval(CI), were significantly decreased from 216 (103-464) and 61 (22-198) pmol/mmol creatinine to 78 (29-159) and 35 (12-118) pmol/mmol creatinine, respectively (p 0.05). According to our clinical results and urinary levels of leukotrienes, which are mediators showing the severity of allergic inflammation, it can be suggested that sublingual immunotherapy may be useful in the treatment of seasonal allergic rhinitis but not of seasonal allergic asthma

Subcutaneous immunotherapy and factors affecting patient compliance

31st Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI) -- JUN 16-20, 2012 -- Geneva, SWITZERLANDWOS: 000310247700305European Acad Allergy & Clin Immunol (EAACI

Turkish experience of oral immunotherapy for cow's milk allergy

European-Academy-of-Allergy-and-Clinical-Immunology Congress -- JUN 07-11, 2014 -- Copenhagen, DENMARKWOS: 000341139400373European Acad Allergy & Clin Immuno