7 research outputs found
Endocrine changes associated with spawning behavior and social stimuli in a wild population of rainbow trout (Salmo Gairdneri). I. Males.
Rainbow trout (Salmo gairdneri) were collected from a natural spawning population at Pennask Lake, B.C. Blood samples were taken from male trout at different stages of spawning and assayed by radioimmunoassay for gonadotropin (GtH), testosterone (T), 11-ketotestosterone (11-KT), and 17α-hydroxy-20β-dihydroprogesterone (17,20-P). Testosterone and 11-KT were detected in the plasma of males in spawning condition: 11-KT was at a higher concentration than T and declined to undetectable levels in postspawning fish. There were striking increases in plasma GtH and 17,20-P in males actively courting nest building females. The increase in 17,20-P was evidently not dependent upon an elevation of the pituitary hormone: 17,20-P remained low in males placed with sexually inactive, unovulated females even though GtH levels rose above levels measured in males isolated from females. The significance of the social control of hormone levels is not clear. There is some evidence that 17,20-P and/or GtH may cause an increase in quantity of the milt, and thus the endocrine response to a sexually active female may serve to synchronize maximum male fertility with oviposition readiness in the female
Endocrine changes associated with spawning behavior and social stimuli in a wild population of rainbow trout (Salmo gairdneri). II. Females
Rainbow trout (Salmo gairdneri) were collected from a natural spawning population at Pennask Lake, B.C. Blood samples taken from female trout at different stages of spawning were assayed by radioimmunoassay for gonadotropin (GtH), estradiol-17 beta (E2), androgens, including testosterone (T), and 17α-hydroxy-20 β-dihydroprogesterone (17,20-P). Plasma levels of androgen and estradiol were highest in females sampled shortly before ovulation (ogreeno females) and declined in ovulated and sexually active females, reaching lowest levels in postspawning fish. Concentrations of 17,20-P rose markedly in ovulated females allowed to dig nests and interact with sexually active males. Plasma GtH levels were similar in green unovulated females and ovulated fish prevented from spawning, but showed a marked increase in actively nest building ovulated fish. The results demonstrate that social stimuli affect plasma levels of 17,20-P and perhaps GtH. The functional significance of the endocrine responses to social factors is not clear, but it is suggested that increased hormone levels may contribute to an acceleration or synchronization of breeding, or be responsible for causing and maintaining more vigorous sexual activity
Protein misfolding and aggregation in Parkinson's disease
10.1089/ars.2009.2490Antioxidants and Redox Signaling1192119-2134ARSI
Lysine 63-linked polyubiquitin potentially partners with p62 to promote the clearance of protein inclusions by autophagy
Autophagy42251-25
The multi-facets of sustainable nanotechnology-Lessons from a nanosafety symposium
10.3109/17435390.2015.1027315Nanotoxicology93404-40