A comparative study on the vitro antimicrobial properties of Psidium guajava leaf extract vs Vancomycin on Methicillin Resistant Staphylococcus aureus (MRSA)

The research was conducted to investigate antibacterial properties in a methanolic leaf extract of P. guajava against Methicilin Resistant Staphylococcus aureus (MRSA) and compare it to that of Vancomycin. Leaf extracts were obtained using a methanol solvent and analysis of its phytochemical properties revealed high levels of flavonoids, saponins, and tannins, compounds to which the antibacterial activity of P. guajava was attributed. The P. guajava leaf extract was serially diluted and was tested its antibacterial activity through Agar dilution method. In both methods, all concentrations of the leaf extract failed to show any inhibitory activity against MRSA, indicating resistance of the organism. The absence of antimicrobial activity of the methanol P. guava leaf extracts may be due to the resistance of the clinical strain, inferior effect of leaf extracts compared to stem barks, less flavonoid and phenolic content extracted by the methanol solvent compared to ethanol solvent, and improper storage of the leaf extract. Further research on P. guajava was recommended to investigate its mechanism of action, medical interactions, and pharmacokinetic profile. Moreover, an alternative method was recommended, such as the well-diffusion method

Relationship between herbal medicine knowledge and self-medication with herbal medicine among 20-45 year old adults in Bagong Bayan District, Dasmarinas, Cavite

A cross sectional-analytic design was utilized in this study. Twenty eight (28) adults aged 20 to 45 years old residing in Bagong Bayan District, Dasmarinas, Cavite in 2016 were chosen as respondents using two-stage cluster sampling. A questionnaire guided interview was the instrument utilized and data was analysed using frequency, proportion, mean, range, and chi-square. Results showed that knowledge on herbal medicine had no significant relationship with self-medication with herbal medicine. It was recommended that further studies should be done to explore the correlation between herbal medicine knowledge and use in Dasmarinas, Cavite. The variables between cultural beliefs and self-medication with herbal medicine could also be explored