Developpement d'un systeme informatise pour la caracterisation de biocapteurs a glucose

SIGLECNRS T Bordereau / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc

The use of microprocessors for the evaluation of the analytical performance of enzyme- based sensors

International audienceBiosensors such as enzyme electrodes, using enzymatic membranes and electrochemical detectors, usually present a great specificity for a given metabolite such as sugar or amino acid (Thévenot et al. 1978,1979; Sternberg et al. 1980). The operating properties and the analytical characteristics ..

Evaluation of Implantable Glucose Enzyme-Based Sensors with Extracorporal Blood Shunt

International audienceThis paper presents several methods and instruments developed for the characterization of enzymatic membranes and enzyme electrodes: 1. amplitude and response time of steady-state and transient responses to glucose, automatically determined with an Apple II based workstation, 2. enzyme electrode response to in vitro simulated I.V.G.T.T. and to in vivo I.V.G.T.T. when connected to an extracorporal blood shunt of conscious rats