426 research outputs found
A New Method of Generation of Bismuthonium Ylides and their Efficient Trapping with Sulphenes
Partial Desulphurization of Dithioacetal Derivatives of Diaryl Ketones and Bis-sulphenylated Active Methylene Compounds using Sodium Telluride under Aprotic Conditions
A Convenient One-pot Preparation of Te-Alkyl Tellurocarboxylates via the Successive Acylation and Alkylation of Telluride Anion. Application to the Synthesis of Alkyl Telluroimidates
Selective Activation of Primary Carboxylic Acids by Electron-rich Triarylbismuthanes. Application to Amide and Ester Synthesis under Neutral Conditions
Enhanced Nucleophilicity of Tris-(2,6-dimethoxyphenyl)bismuthane as Studied by X-ray Crystallography, 17ONMR Spectroscopy and Theoretical Calculations. X-Ray Molecular Structure of Tris-(2,6-dimethoxyphenyl)bismuthane and of Trimesitylbismuthane
Pathobiology and Chemoprevention of Bladder Cancer
Our understanding of the pathogenesis of bladder cancer has improved considerably over the past decade. Translating these novel pathobiological discoveries into therapies, prevention, or strategies to manage patients who are suspected to have or who have been diagnosed with bladder cancer is the ultimate goal. In particular, the chemoprevention of bladder cancer development is important, since urothelial cancer frequently recurs, even if the primary cancer is completely removed. The numerous alterations of both oncogenes and tumor suppressor genes that have been implicated in bladder carcinogenesis represent novel targets for therapy and prevention. In addition, knowledge about these genetic alterations will help provide a better understanding of the biological significance of preneoplastic lesions of bladder cancer. Animal models for investigating bladder cancer development and prevention can also be developed based on these alterations. This paper summarizes the results of recent preclinical and clinical chemoprevention studies and discusses screening for bladder cancer
Tris(2-methoxyphenyl)bismuthane as a Dehydrating Agent with High Template Ability : an Efficient Single-step Synthesis of Macrocyclic Diesters from Diacid Anhydrides and Glycols
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