123 research outputs found

    Stroboscopic oblique-incidence interferometer for motion visualization of stator of ultrasonic motor.

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    AbstractThis paper describes a motion-visualization technique for an ultrasonic motor (USM) by using a stroboscopic oblique-incidence interferometer. Characteristics of USM depend on a vibration mode of a stator which is one of main component of USM. Though there are some visualization techniques of its vibrated mode, it is difficult to visualization. Because the surface of the stator is rough for a light. For visualization such a surface, we focused on an oblique-incidence interferometer. The interferometer is well suited to analyze the rough surface because a scattering at the rough surface is reduced by using an oblique-incidence light. Furthermore, for detecting a vibrated surface, a pulsed light synchronized with stator was used as light source. We have succeeded to detect a periodically movement of fringe patterns of the vibrated stator

    Cytokine expression in human dermal fibroblasts stimulated with eosinophil cationic protein measured by protein array

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    [Background] : Eosinophil cationic protein (ECP) was reported previously to be involved in allergic inflammation with cytotoxic activity. On the other hand, recent studies showed that ECP did not induce cell death but inhibited the growth of cancer-derived cells. Our previous study indicated that human ECP enhanced differentiation of rat neonatal cardiomyocytes and stress fiber formation in Balb/c 3T3 mouse fibroblasts, while the effects of human ECP on human fibroblasts are unknown. [Objective] : The present study was performed to determine the effects of human ECP on cytokine expression in human fibroblasts by protein array. [Methods] : The effects of recombinant human ECP (rhECP) on normal human dermal fibroblasts (NHDF) were examined by assaying cell growth. Furthermore, cytokine expression of NHDF stimulated by ECP, which could influence cell growth, was evaluated by protein array. [Results] : ECP was not cytotoxic but enhanced the growth of NHDF. The peak rhECP concentration that enhanced the cell counts by 1.56-fold was 100 ng/mL, which was significantly different from cultures without ECP stimulation (ANOVA/Scheffe’s test, P < 0.05). Array analyses indicated that ciliary neurotrophic factor (CNTF), neutrophilactivating peptide (NAP)-2, and neurotrophin (NT)-3 were significantly upregulated in NHDF stimulated with 100 ng/mL ECP compared to those without stimulation. [Conclusion] : ECP is not cytotoxic but enhances the growth of NHDF. CNTF, NAP-2, and NT-3 were suggested to be involved in enhancing the growth of NHDF. These findings will contribute to determination of the role of ECP in allergic inflammation. (Asian Pac J Allergy Immunol 2013;31:271-6

    Quiet Diffusion-weighted MR Imaging of the Brain for Pediatric Patients with Moyamoya Disease

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    PURPOSE: Diffusion-weighted MRI (DWI) is an essential sequence for evaluating pediatric patients with moyamoya disease (MMD); however, acoustic noise associated with DWI may lead to motion artifact. Compared with conventional DWI (cDWI), quiet DWI (qDWI) is considered less noisy and able to keep children more relaxed and stable. This study aimed to evaluate the suitability of qDWI compared with cDWI for pediatric patients with MMD. METHODS: In this observational study, MR examinations of the brain were performed either with or without sedation in pediatric patients with MMD between September 2017 and August 2018. Three neuroradiologists independently evaluated the images for artifacts and restricted diffusion in the brain. The differences between qDWI and cDWI were compared statistically using a chi-square test. RESULTS: One-hundred and six MR scans of 56 patients with MMD (38 scans of 15 sedated patients: 6 boys and 9 girls; mean age, 5.2 years; range, 1-9 years; and 68 scans of 42 unsedated patients: 19 boys and 23 girls; mean age, 10.7 years; range, 7-16 years) were evaluated. MR examinations were performed either with or without sedation (except in one patient). In sedated patients, no artifact other than susceptibility was observed on qDWI, whereas four artifacts were observed on cDWI (P = .04). One patient awoke from sedation during cDWI scanning, while no patient awoke from sedation during qDWI acquisition. For unsedated patients, three scans showed artifacts on qDWI, whereas two scans showed artifacts on cDWI (P = .65). Regarding restricted diffusion, qDWI revealed three cases, while two cases were found on cDWI (P = .66). CONCLUSION: qDWI induced fewer artifacts compared with cDWI in sedated patients, and similar frequencies of artifacts were induced by qDWI and by cDWI in unsedated patients. qDWI showed restricted diffusion comparable to cDWI

    Coronary angioscopic findings 9 months after everolimus-eluting stent implantation compared with sirolimus-eluting stents

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    AbstractObjectivesWe assessed angioscopic findings after everolimus-eluting stents (EES) implantation, compared with sirolimus-eluting stents (SES).BackgroundCoronary angioscopy (CAS) provides an opportunity to assess neointimal coverage over stent struts, thrombus, and plaque color by direct visualization. CAS is a useful tool for evaluating stent struts after drug-eluting stent implantation. Angioscopic findings after EES implantation have not been reported before.MethodsWe performed CAS in 23 patients who were treated with EES and 41 patients with SES. CAS was performed 8.5 months after stent implantation. We assessed neointimal coverage, thrombus, and plaque color. We classified neointimal coverage in 4 grades: grade 0=struts were completely exposed; grade 1=struts were visible with dull light reflexion; grade 2=there was no light reflexion from slightly visible struts; grade 3=struts were completely covered.ResultsThere was no significant difference in minimum, maximum, dominant grade of neointimal coverage, and heterogeneity index between EES and SES. Thrombus was less frequently observed in EES than SES (4% vs 29%, p=0.02). When we divided study patients into acute coronary syndrome (ACS) or stable angina pectoris (SAP), there was a tendency toward less thrombus in EES than SES, in both ACS and SAP. Maximum color grade of the plaques was less advanced in EES than SES (p<0.01). Yellow plaques of grade 2 or 3 were less frequent in EES than SES (35% vs 76%, p<0.01).ConclusionsThis study suggested that EES were associated with lower risk of thrombus formation than SES

    A comparative method for evaluating ecosystem services from the viewpoint of public works

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    Nature-based solutions (NbS), such as the implementation of environmental conservation and restoration as public works projects, require accurate and cost-effective assessments of the values related to the projects. The values should represent collective ecosystem services, individual services such as food provision and water purification, and other intangible services. To comprehensively assess such services, we proposed a novel method, which we call the comparative evaluation method. Our method is able to assess the value of each service category of an NbS project from a single questionnaire survey. Survey participants are asked to compare values of multiple services having anchoring prices. Our method determines the permissible economic value of environmental public works (PEP) in response to the quantity of service. The questionnaire results used for analysis are limited to those from respondents who made their PEP evaluation on the basis of their consideration of the appropriate expenditure of taxes. In addition, the method controls for the effect of the satisfaction that a person experiences from doing good deeds to reduce an overestimation of the values of services. Moreover, PEPs are not influenced by the respondent's annual income, age, sex, or educational background, and are based on personal values. Applying this new method, we surveyed residents of the watersheds of Tokyo Bay and Osaka Bay and evaluated nine ecosystem services. Overall, our new method is shown to be an effective method for evaluating the ecosystem services of NbS projects from the viewpoint of public works

    Green port structures and their ecosystem services in highly urbanized Japanese bays

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    Green port structures (i.e. green infrastructure in ports and harbors) featuring habitats for marine organisms have been promoted in Japan as part of a comprehensive policy to reduce the environmental impact of ports and carry out habitat conservation, restoration, and creation. In this study, we evaluated the ecosystem services provided by green port structures in two highly urbanized bays (Tokyo Bay and Osaka Bay) in Japan. Our results show that the provision of some ecosystem services can be limited by circumstances particular to ports and other areas with restricted access. In the case of green port structures that have strong usage restrictions, for example, cultural services can only be provided if relevant authorities are prepared to conduct public events while ensuring participant safety. On the other hand, green port structures with weak usage restrictions are often equipped with incidental facilities such as parking lots and restrooms; these facilities can enhance the provision of cultural services (e.g. recreation and environmental education). Green port structures in highly urbanized bays often have usage restrictions, but their proximity to large populations means that they can potentially provide numerous ecosystem services. However, our study shows that appropriate management goals, such as protecting species and ensuring healthy habitats, are needed to maintain the value of these services in highly urbanized and eutrophic bays

    Bipedal humanoid robot that makes humans laugh with use of the method of comedy and affects their psychological state actively

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    This paper describes the bipedal humanoid robot that makes human laugh with its whole body expression and affect human’s psychological state. In order to realize "Social interaction" between human and robot, the robot has to affect human’s psychological state actively. We focused on "laugh" because it can be thought as a typical example for researching "Social interaction". Looking through a Japanese comedy style called "manzai" or the art of conversation, we picked out several methods for making human laugh. Then we made several skits with the advice of comedians, and made the whole body humanoid robot perform them. Results of experimental evaluation with these skits shows that the robot’s behavior made subjects laugh and change their psychological state seen as a decrease of "Depression" and "Anger"
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