Continuous drawing of poly(ethylene terephthalate) in ethanol and agile functionalization through infusion

To explore the possibility of applying organic-solvent drawing technique to accomplish a process of industrial significance, continuous drawing of as-spun PET fibers in ethanol was performed. The formation of multiple necks, infusion of ethanol into filament along with the uptake of dissolved dye was observed during the continuous drawing of PET filaments. The propagation speed of individual neck increased as the draw ratio increased, while effect of revolution speed of roller on the neck propagation speed was minimal because of the increase of the number density of neck along with the increase in processing speed. Through the monitoring of the drawing tension, it was found that the fluctuation of drawing tension is a source of instability of the drawing process. The installation of a drawing pin was discovered to be useful for the stabilization of the drawing process while increasing the amount of infused ethanol and dye uptake

Antitumor activity of α-pinene in T-cell tumors

T-cell acute leukemia and lymphoma have a poor prognosis. Although new therapeu-tic agents have been developed, their therapeutic effects are suboptimal. α- Pinene, a monoterpene compound, has an antitumor effect on solid tumors; however, few comprehensive investigations have been conducted on its impact on hematologic ma-lignancies. This report provides a comprehensive analysis of the potential benefits of using α- pinene as an antitumor agent for the treatment of T-cell tumors. We found that α- pinene inhibited the proliferation of hematologic malignancies, especially in T- cell tumor cell lines EL-4 and Molt-4, induced mitochondrial dysfunction and re-active oxygen species accumulation, and inhibited NF-κB p65 translocation into the nucleus, leading to robust apoptosis in EL-4 cells. Collectively, these findings suggest that α- pinene has potential as a therapeutic agent for T-cell malignancies, and further investigation is warranted