SumRec: A Framework for Recommendation using Open-Domain Dialogue

Chat dialogues contain considerable useful information about a speaker's interests, preferences, and experiences.Thus, knowledge from open-domain chat dialogue can be used to personalize various systems and offer recommendations for advanced information.This study proposed a novel framework SumRec for recommending information from open-domain chat dialogue.The study also examined the framework using ChatRec, a newly constructed dataset for training and evaluation. To extract the speaker and item characteristics, the SumRec framework employs a large language model (LLM) to generate a summary of the speaker information from a dialogue and to recommend information about an item according to the type of user.The speaker and item information are then input into a score estimation model, generating a recommendation score.Experimental results show that the SumRec framework provides better recommendations than the baseline method of using dialogues and item descriptions in their original form. Our dataset and code is publicly available at https://github.com/Ryutaro-A/SumRecComment: Accepted to PACLIC 202

Charge-dependent anisotropic flow in high-energy heavy-ion collisions from relativistic resistive magneto-hydrodynamic expansion

We have investigated the charge-dependent anisotropic flow in high-energy heavy-ion collisions, using relativistic resistive magneto-hydrodynamics (RRMHD). We consider the optical Glauber model as an initial model of the quark-gluon plasma (QGP) and the solution of the Maxwell equations with source term of the charged particles in two colliding nuclei as initial electromagnetic fields. The RRMHD simulation is performed with these initial conditions in Au-Au and Cu-Au collisions at $\sqrt{s_{\mathrm{NN}}} = 200$ GeV. We have calculated the charge-odd contribution to the directed flow $\Delta v_1$ and elliptic flow $\Delta v_2$ in both collisions based on electric charge distributions as a consequence of RRMHD. Our results show that the $\Delta v_1$ and $\Delta v_2$ are approximately proportional to the electrical conductivity ($\sigma$) of the medium. In the $\sigma=0.023~\mathrm{fm}^{-1}$ case, our result of $\Delta v_1$ is consistent with STAR data in Au-Au collisions. Furthermore, in Cu-Au collisions, $\Delta v_1$ has a non-zero value at $\eta = 0$. We conclude that the charge-dependent anisotropic flow is a good probe to extract the electrical conductivity of the QGP medium in high-energy heavy-ion experiments.Comment: 10 pages, 9 figure

Relativistic resistive magneto-hydrodynamics code for high-energy heavy-ion collisions

We construct a relativistic resistive magneto-hydrodynamic (RRMHD) numerical simulation code for high-energy heavy-ion collisions. We split the system of differential equations into two parts, a non-stiff and a stiff part. For the non-stiff part, we evaluate the numerical flux using HLL approximated Riemann solver and execute the time integration by the second-order of Runge-Kutta algorithm. For the stiff part, which appears in Ampere's law, we integrate the equations using semi-analytic solutions of the electric field. We employ the generalized Lagrange multiplier method to ensure the divergence-free constraint for the magnetic field and Gauss's law. We confirm that our code reproduces well the results of standard RRMHD tests in the Cartesian coordinates. In the Milne coordinates, the code with high conductivity is validated against relativistic ideal MHD tests. We also verify the semi-analytic solutions of the accelerating longitudinal expansion of relativistic resistive magneto-hydrodynamics in high-energy heavy-ion collisions in a comparison with our numerical result. Our numerical code reproduces these solutions.Comment: 16 pages, 14 figure

Changes in Water network Management since the Meiji Era and Issues Regarding Disaster Prevention at the Foot of Mt. Hira in Shiga Prefecture, Japan

In considering Eco-DRR, it is important to use resources and disaster prevention techniques that make the most of the unique ecosystems of each region. The purpose of this study was to analyze the changes in the water network and its management methods since the Meiji period in Minamikomatsu, Otsu City, located at the foot of Mt. Hira. Based on a literature survey of maps and documents stored in Minamikomatsu, interviews, and field surveys, a water network map was created for each period, and the changes in the management of the water network and issues related to disaster prevention were analyzed. As a result, we were able to confirm the traditional wisdom and techniques of water use and drainage by controlling water intake. On the other hand, the system of water network management has changed with the development of government, agriculture, tourism, and residential areas, and integrated management has become difficult. In addition, changes in the shape and flow of waterways and their disappearance have impeded and fragmented the flow in downstream areas, creating problems for disaster prevention. In the future, it will be important to secure and regenerate the continuity of water networks for watershed basin water control, and to establish a comprehensive water network management system

Newly established cell lines from mouse oral epithelium regenerate teeth when combined with dental mesenchyme

The present study attempted to examine whether clonal cell lines of the oral epithelium can differentiate into ameloblasts and regenerate tooth when combined with dental germ mesenchyme. Clonal cell lines with a distinct morphology were established from the oral epithelium of p53-deficient fetal mice at embryonic day 18 (E18). The strain of mouse is shown to be a useful source for establishing clonal and immortalized cell lines from various tissues and at various stages of development. Tooth morphogenesis is almost completed and the oral epithelium is segregated from the dental epithelium at E18. In RT-PCR analysis of cell lines, mucosal epithelial markers (cytokeratin 14) were detected, but ameloblast markers such as amelogenin and ameloblastin were not detected when cells were cultured on plastic dish. They formed stratified epithelia and expressed a specific differentiation marker (CK13) in the upper layer when cultured on feeder layer or on collagen gel for 1–3 wk, demonstrating that they are of oral mucosa origin. Next, bioengineered tooth germs were prepared with cell lines and fetal molar mesenchymal tissues and implanted under kidney capsule for 2–3 wk. Five among six cell lines regenerated calcified structures as seen in natural tooth. Our results indicate that some oral epithelial cells at E18 possess the capability to differentiate into ameloblasts. Furthermore, cell lines established in the present study are useful models to study processes in tooth organogenesis and tooth regeneration

Efficient organic solar cells by penetration of conjugated polymers into perylene pigments

金沢大学理工研究域物質化学系We report here efficient air-stable p-n heterojunction organic solar cells with a structure consisting of an n-type insoluble perylene pigment penetrated by a p-type-conjugated polymer, where the interfacial area for photocurrent generation increases. The solar cells are easily produced by infiltrating a soluble-conjugated polymer intentionally into an opening among insoluble microcrystalline perylene layer under a saturated chloroform vapor. This approach can be regarded as an alternative convenient way to achieve bulk heterojunction solar cells. The cell performance is further enhanced by inserting an additional layer between the electrode and the photoactive layer to confine exciton in the photoactive layer. The overall attempt to improve the cell performance, so far, results in maximum quantum efficiency up to 45% under illumination of 485-nm monochromatic light and power conversion efficiency up to 1.9% under a simulated solar light (AM1.5) with a 100 mW cm-2 intensity. The approach is promising to achieve practical efficiency because tuning the opening size can further widen the photoactive area. © 2004 American Institute of Physics

Case Study: Somatic Sprouts and Halo-Like Amorphous Materials of the Purkinje Cells in Huntington’s Disease

We described a 63-year-old Japanese female with genetically confirmed Huntington’s disease who showed unusual pathological findings in the cerebellum. This case exhibited typical neuropathological features as Huntington’s disease, including severe degeneration of the neostriatum and widespread occurrence of ubiquitin and expanded polyglutamine-positive neuronal intranuclear and intracytoplasmic inclusions. The cerebellum was macroscopically unremarkable; however, somatic sprouts and halo-like amorphous materials of Purkinje cell with a large amount of torpedoes were noteworthy. Furthermore, the Purkinje cells were found to have granular cytoplasmic inclusions. Somatic sprouting is a form of degenerated Purkinje cell exhibited in several specific conditions. Although this finding usually appeared in developmental brains, several neurodegenerative disorders, including Menkes kinky hair disease, familial spinocerebellar ataxia, acute encephalopathy linked to familial hemiplegic migraine, and several other conditions, have been reported showing sprouting from the soma of Purkinje cell. We propose that Huntington’s disease is another degenerative condition associated with these distinct neuropathological findings of Purkinje cell. Abnormally accumulated huntingtin protein in the cytoplasm could be related to the development of these structures. © 2015 Springer Science+Business Media New YorkIn Pres

Porphyrin dye-sensitization of polythiophene in a conjugated polymer/TiO2 p-n hetero-junction solar cell

金沢大学工学部In the blended solid of poly(3-hexylthiophene-2,5-diyl) (P3HT) and porphyrin (TPP)/TiO2 p-n hetero-junction solar cells, a photo-induced charge transfer between P3HT and TPP accelerated the charge separation in the depletion layer formed at the P3HT + TPP/TiO2 interface, enhancing the photovoltaic properties. For the blended cell containing zinc porphyrin as TPP, the energy conversion yield of 0.26% was obtained under the illumination of solar simulated light AM1.5-100 mW/cm2

Immune State Conversion of the Mesenteric Lymph Node in a Mouse Breast Cancer Model

Secondary lymphoid tissues, such as the spleen and lymph nodes (LNs), contribute to breast cancer development and metastasis in both anti- and pro-tumoral directions. Although secondary lymphoid tissues have been extensively studied, very little is known about the immune conversion in mesenteric LNs (mLNs) during breast cancer development. Here, we demonstrate inflammatory immune conversion of mLNs in a metastatic 4T1 breast cancer model. Splenic T cells were significantly decreased and continuously suppressed IFN-gamma production during tumor development, while myeloid-derived suppressor cells (MDSCs) were dramatically enriched. However, T cell numbers in the mLN did not decrease, and the MDSCs only moderately increased. T cells in the mLN exhibited conversion from a pro-inflammatory state with high IFN-gamma expression to an anti-inflammatory state with high expression of IL-4 and IL-10 in early- to late-stages of breast cancer development. Interestingly, increased migration of CD103(+)CD11b(+) dendritic cells (DCs) into the mLN, along with increased (1 -> 3)-beta-D-glucan levels in serum, was observed even in late-stage breast cancer. This suggests that CD103(+)CD11b(+) DCs could prime cancer-reactive T cells. Together, the data indicate that the mLN is an important lymphoid tissue contributing to breast cancer development