222 research outputs found
Silkworm larvae (Bombyx mori) can learn cues associated with finding food
The present study investigated the ability of silkworm Bombyx mori (Lepidoptera: Bombycidae) larvae to learn. Silkworm larvae were trained to consume food that was placed on red paper; consequently they became attracted to red, rather than blue paper even in the absence of food. In contrast, untrained controls had no preference for either red or blue paper. These results suggested that silkworm larvae learned to associate red paper with food, and that they can discriminate colors.
DOI: http://dx.doi.org/10.5281/zenodo.560946
CLASSIFICATION OF FOUR DELIVERY STYLES OF PITCHING MOTON IN YOUNG BASEBALL PLAYERS
The purpose of this study was to examine the release positions of the throwing arm and of the trunk in four delivery styles (overarm, three-quarter arm, sidearm and underarm) of the baseball pitching motion, and to identify criteria to define the four delivery styles based upon the positions of both the trunk and throwing arm (upper arm) segments. Thirty-four pitching motions were videotaped using the 3D DLT method. These motions were qualitatively classified by coaches’ observation into 15 overarm, 7 three-quarter arm, 7 sidearm and 5 underarm deliveries. The angles for the trunk lateral tilt and upper arm elevation in the global coordinate system were quantified, and regression analysis revealed a linear relationship between the two angles. Criteria based on these angles were developed that matched the coaches’ observations well, demonstrating that the baseball pitching motion could be quantitatively classified into the four delivery styles
DIFFERENCES AMONG THE OVERHAND, THREE-QUARTER, SIDEARM AND UNDERHAND DELIVERY STYLES IN BASEBALL PITCHERS
The aim of the study was to clarify the biomechanical differences among the overhand (OS), three-quarter (TS), sidearm (SS) and underhand (US) styles of baseball pitching. About 700 pitches were videotaped using the 3D DLT method. The fastest pitch of each pitcher was used to establish criteria for the separation of the pitches into the four styles based on coaches’ observation and on trunk lateral tilt and upper arm elevation angles. Forty-nine pitches were selected for analysis, and classified into 18 OS, 10 TS, 10 SS and 11 US deliveries. Twenty-six kinematic and kinetic variables were calculated and analyzed. Trunk lateral tilt and upper arm elevation angles were significantly larger in the order OS-TS-SS-US. Ball velocity was significantly slower in the US group than in the other three. Significant differences were found among the groups in six kinematic and five kinetic variables. The slow ball velocity in the US group may have been causally linked to the significantly smaller forces and torques of the US group in relation to the other three
A novel technique for the measurement of the avalanche fluctuation of gaseous detectors
We have developed a novel technique for the measurement of the avalanche
fluctuation of gaseous detectors using a UV laser. The technique is simple and
requires a short data-taking time of about ten minutes. Furthermore, it is
applicable for relatively low gas gains. Our experimental setup as well as the
measurement principle, and the results obtained with a stack of Gas Electron
Multipliers (GEMs) operated in several gas mixtures are presented.Comment: 7 pages, 7 figures. For the proceedings of VCI2016, to be published
in Nucl. Instrum. Methods Phys. Res.
Neuromelanin‐Sensitive Magnetic Resonance Imaging Using DANTE Pulse
BACKGROUND: Neuromelanin-sensitive magnetic resonance imaging techniques have been developed but currently require relatively long scan times. The aim of this study was to assess the ability of black-blood delay alternating with nutation for tailored excitation-prepared T1-weighted variable flip angle turbo spin echo (DANTE T1-SPACE), which provides relatively high resolution with a short scan time, to visualize neuromelanin in the substantia nigra pars compacta (SNpc). METHODS: Participants comprised 49 healthy controls and 25 patients with Parkinson's disease (PD). Contrast ratios of SNpc and hyperintense SNpc areas, which show pixels brighter than thresholds, were assessed between DANTE T1-SPACE and T1-SPACE in healthy controls. To evaluate the diagnostic ability of DANTE T1-SPACE, the contrast ratios and hyperintense areas were compared between healthy and PD groups, and receiver operating characteristic analyses were performed. We also compared areas under the curve (AUCs) between DANTE T1-SPACE and the previously reported gradient echo neuromelanin (GRE-NM) imaging. Each analysis was performed using original images in native space and images transformed into Montreal Neurological Institute space. Values of P < 0.05 were considered significant. RESULTS: DANTE T1-SPACE showed significantly higher contrast ratios and larger hyperintense areas than T1-SPACE. On DANTE T1-SPACE, healthy controls showed significantly higher contrast ratios and larger hyperintense areas than patients with PD. Hyperintense areas in native space analysis achieved the best AUC (0.94). DANTE T1-SPACE showed AUCs as high as those of GRE-NM. CONCLUSIONS: DANTE T1-SPACE successfully visualized neuromelanin of the SNpc and showed potential for evaluating PD. © 2020 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society
Identifying and reverting the adverse effects of white matter hyperintensities on cortical surface analyses
ありふれた脳の白質病変がMRI画像解析を悪化させていた --従来手法に機械学習を組み入れた改善手法の開発--. 京都大学プレスリリース. 2023-10-02.The Human Connectome Project (HCP)-style surface-based brain MRI analysis is a powerful technique that allows precise mapping of the cerebral cortex. However, the strength of its surface-based analysis has not yet been tested in the older population that often presents with white matter hyperintensities (WMHs) on T2-weighted (T2w) MRI (hypointensities on T1w MRI). We investigated T1-weighted (T1w) and T2w structural MRI in 43 healthy middle-aged to old participants. Juxtacortical WMHs were often misclassified by the default HCP pipeline as parts of the gray matter in T1w MRI, leading to incorrect estimation of the cortical surfaces and cortical metrics. To revert the adverse effects of juxtacortical WMHs, we incorporated the Brain Intensity AbNormality Classification Algorithm into the HCP pipeline (proposed pipeline). Blinded radiologists performed stereological quality control (QC) and found a decrease in the estimation errors in the proposed pipeline. The superior performance of the proposed pipeline was confirmed using an originally-developed automated surface QC based on a large database. Here we showed the detrimental effects of juxtacortical WMHs for estimating cortical surfaces and related metrics and proposed a possible solution for this problem. The present knowledge and methodology should help researchers identify adequate cortical surface biomarkers for aging and age-related neuropsychiatric disorders
A multicenter prospective registry of Borden type I dural arteriovenous fistula: results of a 3-year follow-up study
PURPOSE: Although intracranial dural arteriovenous fistula (DAVF) without retrograde leptomeningeal venous drainage (Borden type I) is reported to have a benign nature, no study has prospectively determined its clinical course. Here, we report a 3-year prospective observational study of Borden type I DAVF. METHODS: From April 2013 to March 2016, consecutive patients with DAVF were screened at 13 study institutions. We collected data on baseline characteristics, clinical symptoms, angiography, and neuroimaging. Patients with Borden type I DAVF received conservative care while palliative intervention was considered when the neurological symptoms were intolerable, and were followed at 6, 12, 24, and 36 months after inclusion. RESULTS: During the study period, 110 patients with intracranial DAVF were screened and 28 patients with Borden type I DAVF were prospectively followed. None of the patients had conversion to higher type of Borden classification or intracranial hemorrhage during follow-up. Five patients showed spontaneous improvement or disappearance of neurological symptoms (5/28, 17.9%), and 5 patients showed a spontaneous decrease or disappearance of shunt flow on imaging during follow-up (5/28, 17.9%). Stenosis or occlusion of the draining sinuses on initial angiography was significantly associated with shunt flow reduction during follow-up (80.0% vs 21.7%, p = 0.02). CONCLUSION: In this 3-year prospective study, patients with Borden type I DAVF showed benign clinical course; none of these patients experienced conversion to higher type of Borden classification or intracranial hemorrhage. The restrictive changes of the draining sinuses at initial diagnosis might be an imaging biomarker for future shunt flow reduction
Insertable inductively coupled volumetric coils for MR microscopy in a human 7T MR system
PURPOSE: To demonstrate the capability of insertable inductively coupled volumetric coils for MR microscopy in a human 7T MR system. METHODS: Insertable inductively coupled volume coils with diameters of 26 and 64 mm (D26 and D64 coils) targeted for monkey and mouse brain specimen sizes were designed and fabricated. These coils were placed inside the imaging volume of a transmit/receive knee coil without wired connections to the main system. Signal-to-noise ratio (SNR) evaluations were conducted with and without the insertable coils, and the g-factor maps of parallel imaging (PI) were also calculated for the D64 coil. Brain specimens were imaged using 3D T 2 ∗ -weighted images with spatial resolution of isotropic 50 and 160 μm using D26 and D64 coils, respectively. RESULTS: Relative average (SD) SNRs compared with knee coil alone were 12.54 (0.30) and 2.37 (0.05) at the center for the D26 and D64 coils, respectively. The mean g-factors of PI with the D64 coil for the factor of 2 were less than 1.1 in the left-right and anterior-posterior directions, and around 1.5 in the superior-inferior direction or when the PI factor of 3 was used. Acceleration in two directions showed lower g-factors but suffered from intrinsic low SNR. Representative T 2 ∗ -weighted images of the specimen showed structural details. CONCLUSION: Inductively coupled small diameter coils insertable to the knee coil demonstrated high SNR and modest PI capability. The concept was successfully used to visualize fine structures of the brain specimen. The insertable coils are easy to handle and enable MR microscopy in a human whole-body 7T MRI system
- …