136 research outputs found

    Lotus root-like appearance in the left anterior descending artery treated with a drug-coated balloon angioplasty

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    A lotus root-like appearance of the coronary artery diagnosed by optical coherence tomography (OCT) is characterized by old coronary thrombi that form small lumen channels. Herein, serial OCT images of a left anterior descending artery with a lotus root-like appearance, treated with drug-coated balloon angioplasty are described

    卵生軟骨魚類の発育段階における浸透圧調節機構に関する研究

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    学位の種別: 課程博士審査委員会委員 : (主査)東京大学教授 竹井 祥郎, 東京大学教授 岡 良隆, 東京大学准教授 朴 民根, 東京大学准教授 入江 直樹, 東京大学准教授 兵藤 晋University of Tokyo(東京大学

    Pressure-Induced Ferromagnetic to Nonmagnetic Transition and the Enhancement of Ferromagnetic Interaction in the Thiazyl-Based Organic Ferromagnet γ-BBDTA·GaCl4

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    A thiazyl-based ferromagnet, the γ-phase of BBDTA (i.e., benzo[1,2- d :4,5- d \u27]bis[1,3,2]dithiazole)·GaCl 4 , has a high ferromagnetic ordering temperature of 7.0 K in organic radical ferromagnets. In this system, pressurization generated more compact molecular packing, resulting in that the ferromagnetic state at P = 16.2 kbar is stabilized over a temperature range of more than twice of the initial range. However, the saturation magnetic moment was reduced with increasing pressure, decreasing to about 12% of the initial value even at the low pressure level of P = 1.0 kbar. This suggests that the ferromagnetic molecular packing of the monoclinic γ-phase is easily transformed into that of the diamagnetic phase. Powder X-ray diffraction experiments revealed that the diamagnetic non-monoclinic (α- or β-) phase became stable instead of the monoclinic γ-phase across the pressure of 2.5–5.8 kbar. The increase in the temperature of onset of ferromagnetic state occurs in the surviving ferromagnetic domain surrounded by the diamagnetic domains

    The Effect of Output Processing on Subsequent Input Processing: A Free Recall Study

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    There is now growing evidence that output promotes second language acquisition. Recently, interest has been shown in examining (a) the effect of output processing on subsequent input processing, and (b) what factors mediate that effect. An experiment was conducted for two proficiency levels of Japanese learners of English under two conditions (output and non-output). First, participants in the output condition wrote a story in English based on four cartoon pictures (output task processing). Second, participants in both conditions read a model story describing the four cartoon pictures (subsequent input processing). Third, both sets of participants were asked, without any advance notice, to recall what they had read (written free recall test). Performance on the written free recall test suggests that (a) output tasks facilitated subsequent input processing, and (b) complex relationships existed among L2 proficiency levels, experiment conditions, and linguistic domains during subsequent input processing. These findings are discussed with reference to second language acquisition research. Implications for pedagogical practice are also considered

    Effects of Hydrostatic Pressure and Uniaxial Strain on Spin-Peierls Transition in an Organic Radical Magnet, BBDTA·InCl4

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    We investigated the effects of hydrostatic pressure and uniaxial strain on the spin-Peierls (SP) transition of an organic radical magnet, benzo[1,2-d:4,5-d\u27]bis[1,3,2]dithiazole(BBDTA)·InCl 4 . It has a one-dimensional coordination polymer structure along its c -axis and its SP transition occurs at 108 K. The SP transition temperature T SP decreased to 99 K at a hydrostatic pressure of 10 kbar, while it increased to 132 K at a uniaxial strain along the c -axis of 8 kbar. The pressure dependences of T SP under these two conditions were discussed by evaluating two parameters, namely, the intrachain interaction 2 J / k B and the effective spin–lattice coupling parameter η, that are related to T SP by the equation T SP =1.6η J / k B . Under ambient pressure, the a - and c -axes of this material shortened monotonically with decreasing temperature, while the b -axis elongated below T SP . In this study, we found the correlation between η and the change in the lattice constant b . 2 J / k B increased with increasing hydrostatic pressure and uniaxial strain, suggesting that the contraction along the c -axis does not depend on the manner of pressurization. From the evaluation of η, the observed variation in T SP is explained by the difference between the changes in b under the two pressurization conditions

    Identification and quantification of farmed red sea bream escapees from a large aquaculture area in Japan using microsatellite DNA markers

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    A large number of farmed red sea bream (Pagrus major) and their gametes have escaped and dispersed into the wild from net-cage aquaculture since the advent of the technology in the mid-20th century. These escapees have likely been recruited into wild populations, affecting their genetic diversity. In this study, we used assignment methods with microsatellite markers to assess the frequency of escapee farmed red sea bream within the wild populations in a major aquaculture production region (UWJ) and in two regions with relatively lower production (IWG and SIJ) in Ehime Prefecture, Japan. The frequency of escapees in UWJ ranged from 14.1% to 30.2%, as shown by three methods of assignment. Escapees were frequently identified among specimens caught by angling (ranging from 26.7% to 46.7%), suggesting that they stay in the same area even after escape or are less cautious than wild individuals. No escapee was found in IWG and SIJ, areas with less extensive aquaculture. Some wild-caught fish appeared to have hybridized with farmed fish, as indicated by the threshold of membership coefficients obtained by simulation. These results clearly indicate that large numbers of farmed individuals have escaped from UWJ, a major aquaculture area, since the inception of red sea bream farming in Japan. Genetic reshuffle has possibly occurred following hybridization of wild and farmed individuals

    Sulfate transporters involved in sulfate secretion in the kidney are localized in the renal proximal tubule II of the elephant fish (Callorhinchus milii)

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    Most vertebrates, including cartilaginous fishes, maintain their plasma SO4 (2-) concentration ([SO4 (2-)]) within a narrow range of 0.2-1 mM. As seawater has a [SO4 (2-)] about 40 times higher than that of the plasma, SO4 (2-) excretion is the major role of kidneys in marine teleost fishes. It has been suggested that cartilaginous fishes also excrete excess SO4 (2-) via the kidney. However, little is known about the underlying mechanisms for SO4 (2-) transport in cartilaginous fish, largely due to the extraordinarily elaborate four-loop configuration of the nephron, which consists of at least 10 morphologically distinguishable segments. In the present study, we determined cDNA sequences from the kidney of holocephalan elephant fish (Callorhinchus milii) that encoded solute carrier family 26 member 1 (Slc26a1) and member 6 (Slc26a6), which are SO4 (2-) transporters that are expressed in mammalian and teleost kidneys. Elephant fish Slc26a1 (cmSlc26a1) and cmSlc26a6 mRNAs were coexpressed in the proximal II (PII) segment of the nephron, which comprises the second loop in the sinus zone. Functional analyses using Xenopus oocytes and the results of immunohistochemistry revealed that cmSlc26a1 is a basolaterally located electroneutral SO4 (2-) transporter, while cmSlc26a6 is an apically located, electrogenic Cl(-)/SO4 (2-) exchanger. In addition, we found that both cmSlc26a1 and cmSlc26a6 were abundantly expressed in the kidney of embryos; SO4 (2-) was concentrated in a bladder-like structure of elephant fish embryos. Our results demonstrated that the PII segment of the nephron contributes to the secretion of excess SO4 (2-) by the kidney of elephant fish. Possible mechanisms for SO4 (2-) secretion in the PII segment are discussed
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