Effect of Isatis spp. Extraction on the Growth of Aspergillus niger and Candida albicans

In this study, The crude extraction of Isatis spp. (I.tinctoria, I.busichaina and I. lusitanica) were investigated for their antifungal activity. Each of methanol, ethanol, and H2O was used as a solvent. Due to find the most effective part of each species, the plant parts were used separately. The aim of this research was to determine the effect of the natural product on two common pathogenic fungi Aspergillus niger & Candida albicans. The results show that most of the used plants have a significant effect on both used fungal species. Extracted each of flower, I. tinctoria was shown the best results comparing to the other used species. Extracted leaf and flower of I. tinctoria by methanol was show the best result on Aspergillus niger & Candida albicans. The growth zone was around 90mm for control and  61mm at 75% concentration of methanolic and ethanolic extraction. The flower was for followed by the stem. Depend on the results, the methanol was shown the highest number, then ethanol and the lowest inhibition zone area was for H2O extraction.  &nbsp

A Comparison of Chemical Compounds between Anti-Diabetic Drug and Some Medicinal Plants

Type 2 diabetes (T2D) is a kind of diabetes marked by high blood sugar, insulin, and insulin insufficiency. Adult-onset diabetes is another name for it. Increased thirst, frequent urination, and unexplained weight loss are common indications and symptoms. Metformin side effects include metallic taste, weakness, diarrhea, stomach upset, lactic acidosis, and vomiting. Two other side effects are asthenia and a Vitamin B12 deficiency. Many recent studies and most health experts recommend basil seed as a better Metformin substitute. The research investigates why patients who consume basil seeds have a similar response to those who take Metformin. The methodology of the study consisted of two main steps, first step is to analyze basil and use HPLC to determine its chemical components. The second step is to compare the broken-down components to Metformin-composed materials, which is done by diluting with methanol/water (50:50 v/v) and removing the fat layer using 20 mL hexane. The findings showed that basil seed and Metformin had the most similar component structure, thus the foundlings concluded that patients had the same responses without the Metformin side effects, implying that basil seed stabilizes blood sugar levels

Clinical Prediction of Blood Parameters Associated with Breast, Colon, Thyroid, Ovarian, and Prostate Cancer

Cancer is a cellular change caused by uncontrolled cell growth and division. This disease develops from the growth of abnormal cells that have the potential to invade or spread to other parts of the body. The aim of this study was to investigate the relationship between blood parameters (e.g., Mean corpuscular volume (MCV), Mean corpuscular hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC), Haemoglobin (HGB), White Blood Cell (WBC), and Red Blood Cell (RBC)) and different types of cancer. Breast cancer, thyroid gland cancer, ovarian cancer, testicular cancer, brain tumors as well as other types of cancer are based on the cell of the tissue found on or in the body. Any of these types of cancer are associated with a variety of health issues that put the patient's life in danger. Performing the complete blood count (CBC) test prior to or after a cancer diagnosis is necessary as abnormalities in the body can cause blood component rates to either increase or decrease, depending on the type of cancer, the patient's physiological mechanism, and the structural component. Since the CBC test belongs to hematology, drawing a blood sample and putting it into the anticoagulant tube for testing were preferred. In this study, the blood components of almost all patients were normal except for a few of them which may be due to other medical and biological factors. There is a significant relationship between blood parameters and cancer types.&nbsp