Super-Virasoro Anomaly, Super-Weyl Anomaly and the Super-Liouville Action for 2D Supergravity

The relation between super-Virasoro anomaly and super-Weyl anomaly in $N=1$ NSR superstring coupled with 2D supergravity is investigated from canonical theoretical view point. The WZW action canceling the super-Virasoro anomaly is explicitly constructed. It is super-Weyl invariant but nonlocal functional of 2D supergravity. The nonlocality can be remedied by the super-Liouvlle action, which in turn recovers the super-Weyl anomaly. The final gravitational effective action turns out to be local but noncovariant super-Liouville action, describing the dynamical behavior of the super-Liouville fields. The BRST invariance of this approach is examined in the superconformal gauge and in the light-cone gauge.Comment: 45 page

Long-Term Follow-up Posthematopoietic Stem Cell Transplantation in a Japanese Patient with Type-VII Mucopolysaccharidosis

The effectiveness of hematopoietic stem cell transplantation (HSCT) for type-VII mucopolysaccharidosis (MPS VII, Sly syndrome) remains controversial, although recent studies have shown that it has a clinical impact. In 1998, Yamada et al. reported the first patient with MPS VII, who underwent HSCT at 12 years of age. Here, we report the results of a 22-year follow-up of that patient post-HSCT, who harbored the p.Ala619Val mutation associated with an attenuated phenotype. The purpose of this study was to evaluate changes in physical symptoms, the activity of daily living (ADL), and the intellectual status in the 34-year-old female MPS VII patient post-HSCT, and to prove the long-term effects of HSCT in MPS VII. Twenty-two years after HSCT, the β-glucuronidase activity in leukocytes remained at normal levels, and urinary glycosaminoglycan excretion was reduced and kept within normal levels. At present, she is capable of sustaining simple conversation, and her intellectual level is equivalent to that of a 6-year-old. She can walk alone and climb upstairs by holding onto a handrail, although she feels mild pain in the hip joint. The cervical vertebrae are fused with the occipital bone, causing dizziness and light-headedness when the neck is bent back. Overall, her clinical condition has been stabilized and kept well for long-term post-HSCT, indicating that HSCT is a therapeutic option for MPS VII

正準形式に基づく2次元超重力理論のBRST量子化とアノマリー

取得学位：博士(理学)，学位授与番号：博甲第262号，学位授与年月日：平成10年9月30日,学位授与年：199

Level of interest in video clips modulates event-related potentials to auditory probes

This study examined whether a participant's level of interest in visual materials could be assessed by event-related potentials to auditory probe stimuli. Twelve young adults performed an auditory target detection task while viewing either interesting or less interesting (neutral) silent video clips. The auditory probe stimuli consisted of target (2000 Hz, p=0.15), standard (1800 Hz, p=0.70), and nontarget deviant (500 Hz, p=0.15) tones. Button press responses to target tones were required. Both target and deviant tones elicited a large P3 wave, the amplitude of which was smaller while participants were viewing interesting video clips than neutral video clips or simple still images (control condition). The amplitude reduction of the P3 to deviant tones was more prominent than that of the P3 to target tones. The difference between the neutral and control conditions was significant only for the deviant P3. The three-tone probe task using perceptually deviant, nontarget stimuli may be a useful objective method to assess how strongly a visual material attracts the viewer's attention

Comparison of Liquid Chromatography–Tandem Mass Spectrometry and Sandwich ELISA for Determination of Keratan Sulfate in Plasma and Urine

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