A long-term perspective on a modern drought in the American Southeast

The depth of the 2006-9 drought in the humid, southeastern US left several metropolitan areas with only a 60-120 day water supply. To put the region's recent drought variability in a long-term perspective, a dense and diverse tree-ring network—including the first records throughout the Apalachicola-Chattahoochee-Flint river basin—is used to reconstruct drought from 1665 to 2010 CE. The network accounts for up to 58.1% of the annual variance in warm-season drought during the 20th century and captures wet eras during the middle to late 20th century. The reconstruction shows that the recent droughts are not unprecedented over the last 346 years. Indeed, droughts of extended duration occurred more frequently between 1696 and 1820. Our results indicate that the era in which local and state water supply decisions were developed and the period of instrumental data upon which it is based are amongst the wettest since at least 1665. Given continued growth and subsequent industrial, agricultural and metropolitan demand throughout the southeast, insights from paleohydroclimate records suggest that the threat of water-related conflict in the region has potential to grow more intense in the decades to come

ASLPrep: a platform for processing of arterial spin labeled MRI and quantification of regional brain perfusion

Arterial spin labeled (ASL) magnetic resonance imaging (MRI) is the primary method for noninvasively measuring regional brain perfusion in humans. We introduce ASLPrep, a suite of software pipelines that ensure the reproducible and generalizable processing of ASL MRI data