Neutron and proton spectra from the decay of Λ\Lambda hypernuclei

We have determined the spectra of neutrons and protons following the decay of $\Lambda$ hypernuclei through the one- and two-nucleon induced mechanisms. The momentum distributions of the primary nucleons are calculated and a Monte Carlo simulation is used to account for final state interactions. From the spectra we calculate the number of neutrons ($N_n$) and protons ($N_p$) per $\Lambda$ decay and show how the measurement of these quantities, particularly $N_p$, can lead to a determination of $\Gamma_n / \Gamma_p$, the ratio of neutron to proton induced $\Lambda$ decay. We also show that the consideration of the two-nucleon induced channel has a repercussion in the results, widening the band of allowed values of $\Gamma_n / \Gamma_p$ with respect to what is obtained neglecting this channel.Comment: 30 pages, 12 Postscript figures, uuencoded file, ReVTeX, epsf.st

“Where, O Death, Is Thy Sting?” A Brief Review of Apoptosis Biology

Apoptosis was a term introduced in 1972 to distinguish a mode of cell death with characteristic morphology and apparently regulated, endogenously driven mechanisms. The effector processes responsible for apoptosis are now mostly well known, involving activation of caspases and Bcl2 family members in response to a wide variety of physiological and injury-induced signals. The factors that lead of the decision to activate apoptosis as opposed to adaptive responses to such signals (e.g. autophagy, cycle arrest, protein synthesis shutoff) are less well understood, but the intranuclear Promyelocytic Leukaemia Body (PML body) may create a local microenvironment in which the audit of DNA damage may occur, informed by the extent of the damage, the adequacy of its repair and other aspects of cell status