8 research outputs found
Observation of An Evolving Magnetic Flux Rope Prior To and During A Solar Eruption
Explosive energy release is a common phenomenon occurring in magnetized
plasma systems ranging from laboratories, Earth's magnetosphere, the solar
corona and astrophysical environments. Its physical explanation is usually
attributed to magnetic reconnection in a thin current sheet. Here we report the
important role of magnetic flux rope structure, a volumetric current channel,
in producing explosive events. The flux rope is observed as a hot channel prior
to and during a solar eruption from the Atmospheric Imaging Assembly (AIA)
telescope on board the Solar Dynamic Observatory (SDO). It initially appears as
a twisted and writhed sigmoidal structure with a temperature as high as 10 MK
and then transforms toward a semi-circular shape during a slow rise phase,
which is followed by fast acceleration and onset of a flare. The observations
suggest that the instability of the magnetic flux rope trigger the eruption,
thus making a major addition to the traditional magnetic-reconnection paradigm.Comment: 13 pages, 3 figure
Voltage dependence of synaptic plasticity is essential for rate based learning with short stimuli
Abstract In computational neuroscience, synaptic plasticity rules are often formulated in terms of firing rates. The predominant description of in vivo neuronal activity, however, is the instantaneous rate (or spiking probability). In this article we resolve this discrepancy by showing that fluctuations of the membrane potential carry enough information to permit a precise estimate of the instantaneous rate in balanced networks. As a consequence, we find that rate based plasticity rules are not restricted to neuronal activity that is stable for hundreds of milliseconds to seconds, but can be carried over to situations in which it changes every few milliseconds. We illustrate this, by showing that a voltage-dependent realization of the classical BCM rule achieves input selectivity, even if stimulus duration is reduced to a few milliseconds each
Involvement of Advanced Practice Nurse in the Management of Geriatric Conditions: Examples from Different Countries
Brain microglia in psychiatric disorders
Summary The role of immune activation in psychiatric disorders has attracted considerable attention over the past two decades, contributing to the rise of a new era for psychiatry. Microglia, the macrophages of the brain, are progressively becoming the main focus of the research in this field. In this Review, we assess the literature on microglia activation across different psychiatric disorders, including post-mortem and in-vivo studies in humans and experimental studies in animals. Although microglia activation has been noted in all types of psychiatric disorder, no association was seen with specific diagnostic categories. Furthermore, the findings from these studies highlight that not all psychiatric patients have microglial activation. Therefore, the cause of the neuroinflammation in these cohorts and its implications are unclear. We discuss psychosocial stress as one of the main factors determining microglial activation in patients with psychiatric disorders, and explore the relevance of these findings for future treatment strategies