8 research outputs found
A Case of Hypersensitivity Syndrome Associated with Drug-induced Bronchitis due to Zonisamide.
No full textA Case of Hypersensitivity Syndrome due to Phenobarbital with Another Hyperreaction of Ticlopidine Hydrochloride-Including the follow-up Findings of the HHV-6 IgG Titer during a One-year Period-
No full textA Case of Hypersensitivity Syndrome by Drugs for Neuropathic Pain During Gefitinib Therapy
No full text
Gastric Perforation due to Iatrogenic Immunodeficiency-associated Lymphoproliferative Disorder during the Treatment of Rheumatoid Arthritis
No full textGastric Perforation due to Iatrogenic Immunodeficiency-associated Lymphoproliferative Disorder during the Treatment of Rheumatoid Arthritis
Get PDFA 71-year-old woman being treated with methotrexate (MTX) and tacrolimus (TAC) for rheumatoid arthritis (RA) was admitted to our hospital and underwent surgery for gastric perforation and peritonitis. An endoscopic examination six days post-surgery showed an extensive ulcer in the stomach, and a biopsy revealed diffused large B-cell lymphoma. We diagnosed her with immunodeficiency-associated lymphoproliferative disorder (LPD) and discontinued the MTX and TAC. She underwent gastrectomy due to stenosis approximately two months after the first operation, but the histopathological findings of lymphoma had disappeared. LPD should be considered as a potential cause of gastric perforation during RA treatment. c 2019 Japanese Society of Internal Medicine
