10 research outputs found
Variability of Brown Dwarfs
Brown dwarfs constitute a missing link between low-mass stars and giant
planets. Their atmospheres display chemical species typical of planets, and one
could wonder whether they also have weather-like patterns. While brown dwarf
surface features cannot be directly resolved, the photometric and spectroscopic
modulations induced by these features, as they rotate in and out of view,
provide a wealth of information on the evolution of their atmosphere. A review
of brown dwarfs variability through the L, T and Y spectral types sequence is
presented, as well as the constraints that they set on the nature of
weather-like patterns on their surface.Comment: Accepted chapter in the "Handbook of Exoplanets"; Springe
Natural anti-CCR5 antibodies in HIV-infection and -exposure
Natural antibodies constitute a first-line of defence against pathogens; they may also play other roles in immune regulation and homeostasis, through their ability to bind host antigens, surface molecules and receptors. Natural anti-CCR5 antibodies can be decisive in preventing HIV infection in mucosal tissues and offer prompt and effective protection just at major sites of virus entry. Among natural anti-CCR5 antibodies, IgG and IgA to the ECL1 domain have been shown to block HIV effectively and durably without causing harm to the host. Their biological properties and their uncommon generation in subsets of HIV-infected and HIV-exposed individuals (so called ESN) will be introduced and discussed, with the aim at exploiting their potential in therapy and prevention