Assessing muscle strength asymmetry via a unilateral stance isometric mid-thigh pull

Purpose: The purpose of this study was to investigate the within-session reliability of bilateral and unilateral stance isometric mid-thigh pull (IMTP) force-time characteristics including peak force (PF), relative PF and impulse at time bands (0-100, 0-200, 0-250 and 0-300 ms); and to compare isometric force-time characteristics between right and left and dominant (D) and non–dominant (ND) limbs. Methods: Professional male Rugby league and multi-sport collegiate male athletes (n=54, age 23.4 ± 4.2 years, height 1.80 ± 0.05 m, mass:88.9 ± 12.9 kg) performed 3 bilateral IMTP trials, and 3 unilateral stance IMTP trials per leg 60 on a force plate sampling at 600 Hz. Results: Intraclass correlation coefficients (ICC) and coefficients of variation (CV) demonstrated high-within session reliability for bilateral and unilateral IMTP PF (ICC =.94, CV = 4.7–5.5%). Lower reliability measures and greater variability were observed for bilateral and unilateral IMTP impulse at time bands (ICC =.81-.88, CV =7.7-11.8%). Paired sample t-tests and Cohen’s d effect sizes revealed no significant differences for all isometric force-time characteristics between right and left limbs in collegiate male athletes (p >.05, d ≤0.32) and professional rugby league players (p >.05, d ≤0.11), however significant differences were found between D and ND limbs in male collegiate athletes (p <.001, d = 0.43–0.91) and professional rugby league players (p < .001, d = 0.27–0.46). Conclusion: This study demonstrated high within-session reliability for unilateral stance IMTP PF;revealing significant differences in isometric force-time characteristics between D and ND limbs in male athletes

A comparison of dynamic strength index between team-sport athletes

The purpose of this study was to examine the differences in countermovement jump peak force (CMJ-PF), isometric mid-thigh pull peak force (IMTP-PF), and resultant dynamic strength index (DSI) values between team-sport athletes. One hundred and fifteen male and female team-sport athletes performed the CMJ and IMTP to determine peak force (CMJ-PF and IMTP-PF, respectively). Statistically and practically significant differences (p ≤ 0.050; d = 0.49–1.32) in CMJ-PF were evident between teams. Specifically, the greatest CMJ-PFs were produced by the male cricket players and were followed in order by the male basketball, male soccer, female netball, female cricket, and female soccer players. Statistically and practically significant differences (p ≤ 0.045; d = 0.64–1.78) in IMTP-PF existed among sports teams, with the greatest IMTP-PFs were produced by the male soccer players and were followed in order by the male cricket, male basketball, female netball, female soccer, and female cricket players. Statistically and practically significant differences (p ≤ 0.050; d = 0.92–1.44) in DSI were found between teams. These findings demonstrate that CMJ-PF, IMTP-PF, and DSI differ between sports teams and provide normative data for ballistic and isometric PF measures. Strength and conditioning coaches should consider relative changes in CMJ-PF and IMTP-PF when assessing DSI ratios

Eave tubes for malaria control in Africa: a modelling assessment of potential impact on transmission.

BACKGROUND: Novel interventions for malaria control are necessary in the face of problems such as increasing insecticide resistance and residual malaria transmission. One way to assess performance prior to deployment in the field is through mathematical modelling. Modelled here are a range of potential outcomes for eave tubes, a novel mosquito control tool combining house screening and targeted use of insecticides to provide both physical protection and turn the house into a lethal mosquito killing device. METHODS: The effect of eave tubes was modelled by estimating the reduction of infectious mosquito bites relative to no intervention (a transmission metric defined as relative transmission potential, RTP). The model was used to assess how RTP varied with coverage when eave tubes were used as a stand-alone intervention, or in combination with either bed nets (LLINs) or indoor residual spraying (IRS). RESULTS: The model indicated the impact of eave tubes on transmission increases non-linearly as coverage increases, suggesting a community level benefit. For example, based on realistic assumptions, just 30 % coverage resulted in around 70 % reduction in overall RTP (i.e. there was a benefit for those houses without eave tubes). Increasing coverage to around 70 % reduced overall RTP by >90 %. Eave tubes exhibited some redundancy with existing interventions, such that combining interventions within properties did not give reductions in RTP equal to the sum of those provided by deploying each intervention singly. However, combining eave tubes and either LLINs or IRS could be extremely effective if the technologies were deployed in a non-overlapping way. CONCLUSION: Using predictive models to assess the benefit of new technologies has great value, and is especially pertinent prior to conducting expensive, large scale, randomized controlled trials. The current modelling study indicates eave tubes have considerable potential to impact malaria transmission if deployed at scale and can be used effectively with existing tools, especially if they are combined strategically with, for example, IRS and eave tubes targeting different houses.This work was supported by European Union Seventh Framework Programme Grant 306105, FP7-HEALTH-2012-INNOVATION-1

Biophotonic Tools in Cell and Tissue Diagnostics.

In order to maintain the rapid advance of biophotonics in the U.S. and enhance our competitiveness worldwide, key measurement tools must be in place. As part of a wide-reaching effort to improve the U.S. technology base, the National Institute of Standards and Technology sponsored a workshop titled "Biophotonic tools for cell and tissue diagnostics." The workshop focused on diagnostic techniques involving the interaction between biological systems and photons. Through invited presentations by industry representatives and panel discussion, near- and far-term measurement needs were evaluated. As a result of this workshop, this document has been prepared on the measurement tools needed for biophotonic cell and tissue diagnostics. This will become a part of the larger measurement road-mapping effort to be presented to the Nation as an assessment of the U.S. Measurement System. The information will be used to highlight measurement needs to the community and to facilitate solutions

Comparison of change of direction speed performance and asymmetries between team-sport athletes : application of change of direction deficit

The purpose of this study was twofold: (1) to examine differences in change of direction (COD) performance and asymmetries between team-sports while considering the effects of sex and sport; (2) to evaluate the relationship between linear speed, COD completion time, and COD deficit. A total of 115 (56 males, 59 females) athletes active in cricket, soccer, netball, and basketball performed the 505 for both left and right limbs and a 10-m sprint test. All team-sports displayed directional dominance (i.e., faster turning performance/shorter COD deficits towards a direction) (p ≤ 0.001, g = −0.62 to −0.96, −11.0% to −28.4%) with, male cricketers tending to demonstrate the greatest COD deficit asymmetries between directions compared to other team-sports (28.4 ± 26.5%, g = 0.19–0.85), while female netballers displayed the lowest asymmetries (11.0 ± 10.1%, g = 0.14–0.86). Differences in sprint and COD performance were observed between sexes and sports, with males demonstrating faster 10-m sprint times, and 505 times compared to females of the same sport. Male soccer and male cricketers displayed shorter COD deficits compared to females of the same sport; however, female court athletes demonstrated shorter COD deficits compared to male court athletes. Large significant associations (ρ = 0.631–0.643, p < 0.001) between 505 time and COD deficit were revealed, while trivial, non-significant associations (ρ ≤ −0.094, p ≥ 0.320) between COD deficit and 10-m sprint times were observed. In conclusion, male and female team-sport athletes display significant asymmetries and directional dominance during a high approach velocity 180° turning task. Coaches and practitioners are advised to apply the COD deficit for a more isolated measure of COD ability (i.e., not biased towards athletes with superior acceleration and linear speed) and perform COD speed assessments from both directions to establish directional dominance and create a COD symmetry profile

Alterations in mosquito behaviour by malaria parasites: potential impact on force of infection

BACKGROUND: A variety of studies have reported that malaria parasites alter the behaviour of mosquitoes. These behavioural alterations likely increase transmission because they reduce the risk of vector death during parasite development and increase biting after parasites become infectious. METHODS: A mathematical model is used to investigate the potential impact of these behavioural alterations on the lifetime number of infectious bites delivered. The model is used to explore the importance of assumptions about the magnitude and distribution of mortality as well as the importance of extrinsic incubation period and gonotrophic cycle length. Additionally, the model is applied to four datasets taken from actual transmission settings. RESULTS: The impact of behavioural changes on the relative number of lifetime bites is highly dependent on assumptions about the distribution of mortality over the mosquito-feeding cycle. Even using fairly conservative estimates of these parameters and field collected data, the model outputs suggest that altered feeding could easily cause a doubling in the force of infection. CONCLUSIONS: Infection-induced behavioural alterations have their greatest impact on the lifetime number of infectious bites in environments with high feeding-related adult mortality and many pre-infectious feeding cycles. Interventions that increase feeding-associated mortality are predicted to amplify the relative fitness benefits and hence enhance the strength of selection for behavioural alteration.This study was supported by the NIH-NIAID ICEMR award (#U19AI089676-01)

The application of change of direction deficit to evaluate cutting ability

The purpose of this study was to examine the application of the change of direction deficit (CODD) to a 90° cut test in order to examine whether CODD provides a unique evaluation of an individual’s cutting ability. Thirty-six male collegiate team–sport (23 Rugby/ 13 Soccer) athletes (age: 20 ± 1.4 years; height: 1.80 ± 0.08 m; mass: 83 ± 13.2 kg) participated in the study. Each athlete performed 3 trials of a 20 m sprint (with 5 m and 10 m splits) and 2 change of direction [COD] tests (90° cut and 505 tests) cutting/ turning from both limbs. Completion times for all sprint and COD tests were measured using timing cells. For both COD tests, CODD was determined (COD completion time – 10 m sprint time). Pearson’s correlation was used to explore relationships between sprint times and CODD and completion times. Significant (P 0.05) trivial to small correlations (r ≤ 0.199) were found between sprint variables and 90° cut CODD. Significant (P < 0.001) large to very large correlations (r ≥ 0.531) were revealed between left and right 90° cut and 90° cut CODD. The results suggest the CODD could be applied to isolate and assess cutting ability in COD speed tests that involve a single cutting maneuver. Failure to inspect CODD could lead to incorrect evaluation of an athletes cutting or COD ability

The effect of training interventions on change of direction biomechanics associated with increased anterior cruciate ligament loading : a scoping review

Change of direction (COD) manoeuvres are associated with anterior cruciate ligament (ACL) injury risk due to the propensity to generate large multiplanar knee joint loads. Given the short- and long-term consequences of ACL injury, practitioners are interested in methods that reduce knee joint loads and subsequent ACL loading. An effective strategy to reduce ACL loading is modifying an athlete's movement mechanics to reduce knee joint loading. The purpose of this scoping review was to critically appraise and comprehensively synthesise the existing literature related to the effects of training interventions on COD biomechanics associated with increased knee joint loads and subsequent ACL loading, and identify gaps and recommend areas for future research. A review of the literature was conducted using Medline and Sport DISCUS databases. Inclusion criteria consisted of pre-post analysis of a COD task, a minimum 4-week training intervention, and assessments of biomechanical characteristics associated with increased ACL loading. Of the 1,027 articles identified, 22 were included in the scoping review. Based on current literature, balance training and COD technique modification are the most effective training modalities for reducing knee joint loading (small to moderate effect sizes). One study reported dynamic core stability training was effective in reducing knee joint loads, but further research is needed to definitively confirm the efficacy of this method. Perturbation-enhanced plyometric training, the F-MARC 11 + soccer specific warm-up, Oslo Neuromuscular warm-up, and resistance training are ineffective training modalities to reduce COD knee joint loads. Conflicting findings have been observed for the Core-Pac and mixed training programme. Consequently, practitioners should consider incorporating balance and COD technique modification drills into their athletes' training programmes to reduce potentially hazardous knee joint loads when changing direction. However, training intervention studies can be improved by investigating larger sample sizes (> 20), including a control group, acknowledging measurement error when interpreting their findings, and considering performance implications, to confirm the effectiveness of training interventions and improve adherence

Assessing asymmetries in change of direction speed performance; application of change of direction deficit

The aims of this study were to quantify asymmetries in change of direction (COD) performance via completion time and COD deficit, and determine its influence on asymmetry profiling of COD ability. A secondary aim was to evaluate the relationship between linear speed, 505 time and COD deficit. Forty-three youth netball athletes (age: 15.4 ± 1.1 years, height: 1.71 ± 0.06 m, mass: 63.3 ± 6.6 kg) performed the 505 for both left and right limbs and a 10 m sprint test. Asymmetries in 505 completion time and COD deficit were quantified for dominant (D) (faster) and non-dominant (ND) (slower) directions. Paired sample t-tests revealed significant differences between D and ND directions for 505 time and COD deficit (p < 0.0001, g = -0.53 to -0.60). Substantially greater asymmetries for COD deficit were observed compared to 505 time (p < 0.0001, g = 1.03). Only two subjects displayed an asymmetry ≥10% based on 505 times. Conversely, based on COD deficit, 21 subjects demonstrated asymmetries ≥10%. Large significant associations were observed between 505 time and COD deficit (r = 0.500-0.593, p ≤ 0.002). Large significant inverse associations were demonstrated between 10 m sprint time and COD deficit (r = -0.539 to -0.633, p ≤ 0.001) indicating faster athletes had longer COD deficits. Nine subjects were classified differently for COD ability when comparing standardized scores for 505 time versus COD deficit. Quantification of asymmetries in COD ability should be based on COD deficits; inspection of 505 times only could lead to misinterpretations of an athlete’s COD symmetry and COD ability. Faster youth netball athletes demonstrate longer COD deficits, thus, researchers and practitioners are encouraged to improve their youth netball athletes’ ability to rapidly decelerate, change direction and reaccelerate from 180° turns

Effect of different onset thresholds on isometric midthigh pull force-time variables

Various thresholds have been used to identify the onset of contraction during isometric midthigh pull (IMTP); however, no agreed onset threshold exists for this assessment. The purpose of this study was to compare relative body weight (BW) and arbitrary onset thresholds to a criterion onset threshold 5 SDs of BW for IMTP force-time variables; force at each threshold, peak force, time-specific force values (100, 150, and 200 ms), and rate of force development (RFD) during 0–100, 0–150, 0–200 ms. Academy rugby league players (n = 9, age: 18.5 6 0.4 years; height: 1.82 6 0.09 m; mass: 91.2 6 13.1 kg) performed 2 IMTP trials on a force platform sampling at 1,000 Hz. The neutral force-time data pool (18 trials) was analyzed with five different thresholds and compared with criterion threshold to determine any variance in force-time variables. Five SDs of BW were significantly lower than 10% BW and 75 N for threshold force which led to significantly greater time-specific force values at 100 and 150 ms and unacceptable limits of agreements (LOA) for all force-time variables. No significant differences (p . 0.05) were observed between 2.5% and 5 SDs of BW; and between 5% and 5 SDs of BW for threshold force and all force-time variables with acceptable LOA. The 5 SDs of BW and 2.5% BW onset thresholds consistently resulted in the lowest values for threshold force, time-specific force values, and RFD, attributed to a lower onset bias. Therefore, scientists and practitioners are recommended to use a 5 SD of BW onset threshold for time-specific force values and RFD for accurate data because it accounts for signal noise during the weighing period. Subsequently, there is greater certainty that the onset of contraction identifies a true meaningful change in force, in contrast to relative BW thresholds