5 research outputs found
HPLC–MS/MS analysis of degradation products of neosalvarsan in a 76-year-old injection preparation
- Author
- AS Levinson
- D Kirchhoff
- F Bosch
- GB Roth
- GB Roth
- GW Raiziss
- H Cousin
- H Peng
- J Drews
- J Greene
- Jan Babica
- K Kudláček
- K Kudláček
- K Nesměrák
- Karel Kudláček
- Karel Nesměrák
- KJ Williams
- L Cantrell
- M Zilker
- Martin Štícha
- MH Florêncio
- MY Kraft
- MY Kraft
- NC Lloyd
- OM Ni Dhubhghaill
- P Ehrlich
- P Masucci
- PA Kober
- Petr Kozlík
- R Brdicka
- RL Wershaw
- S Gibaud
- S Riethmiller
- TF Probey
- W Sneader
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Highly sensitive pyrogen detection on medical devices by the monocyte activation test
- Author
- AI Braude
- C Monn
- CA Dinarello
- DW Watson
- E Atkins
- E Atkins
- F Tokunaga
- GS Kobayashi
- Hans-Peter Wendel
- HD Lemke
- I Ginsburg
- Iwan Anton Burgener
- J Levin
- J Levin
- J Rotta
- JL Ding
- JM Lipton
- Katharina Stang
- L Werner
- M Hasiwa
- M Pfeiffer
- Marcell Post
- MV Sefton
- P Dijck van
- P Gallay
- PV Mohanan
- RE Wilsnack
- S Aulock von
- S Fennrich
- S Fennrich
- S Morath
- Sandra Stoppelkamp
- SE Greisman
- Stefan Fennrich
- Stefanie Krajewski
- T Hartung
- T Hartung
- T Hartung
- TF Probey
- Publication venue
- Publication date
- 01/01/2014
- Field of study
Pyrogens are components of microorganisms, like bacteria, viruses or fungi, which can induce a complex inflammatory response in the human body. Pyrogen contamination on medical devices prior operation is still critical and associated with severe complications for the patients. The aim of our study was to develop a reliable test, which allows detection of pyrogen contamination on the surface of medical devices. After in vitro pyrogen contamination of different medical devices and incubation in a rotation model, the human whole blood monocyte activation test (MAT), which is based on an IL-1β-specific ELISA, was employed. Our results show that when combining a modified MAT protocol and a dynamic incubation system, even smallest amounts of pyrogens can be directly detected on the surface of medical devices. Therefore, screening of medical devices prior clinical application using our novel assay, has the potential to significantly reduce complications associated with pyrogen-contaminated medical devices
Highly sensitive pyrogen detection on medical devices by the monocyte activation test
- Author
- AI Braude
- C Monn
- CA Dinarello
- DW Watson
- E Atkins
- E Atkins
- F Tokunaga
- GS Kobayashi
- Hans-Peter Wendel
- HD Lemke
- I Ginsburg
- Iwan Anton Burgener
- J Levin
- J Levin
- J Rotta
- JL Ding
- JM Lipton
- Katharina Stang
- L Werner
- M Hasiwa
- M Pfeiffer
- Marcell Post
- MV Sefton
- P Dijck van
- P Gallay
- PV Mohanan
- RE Wilsnack
- S Aulock von
- S Fennrich
- S Fennrich
- S Morath
- Sandra Stoppelkamp
- SE Greisman
- Stefan Fennrich
- Stefanie Krajewski
- T Hartung
- T Hartung
- T Hartung
- TF Probey
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Syphilis
- Author
- A Bessemans
- A Costa
- A Gelperin
- A Jouve
- A Klein
- A Rosenthal
- A Schoch
- A. O. F. Ross
- AB Loveman
- AB Loveman
- AC Curtis
- AC Curtis
- AE Wilkinson
- AE Wilkinson
- AE Wilkinson
- AG Bellone
- AG Scnocn
- AH Wheeler
- AH Wheeler
- AJ Berger
- AJ Evans
- AM Hotter
- AM Minno
- AN Roy
- AV Deibert
- AV Ferrari
- AV Ferrari
- B Friedman
- BD Davis
- Benedetti-Valentini
- Birndesenn
- BJ Hanley
- C Chapuis
- C Levaditi
- C. A. Smith
- CA Smith
- CF Mohr
- CN Frazier
- CN Frazier
- Coonwin
- CR Rein
- CR Rein
- CS Nicol
- CW Barnett
- CW Chacko
- CW Chacko
- DD Dexter
- DH Hollander
- DJ Macpherson
- DK Kitchen
- DM Pillsbury
- D’Alessandro
- D’Alessandro
- E Bruusgaard
- E Pesta
- E Thomas
- EB Howard
- ED Delamater
- EG Hampp
- EH Lossing
- EK Stratton
- EM Dunlop
- EM Lourie
- ER Harrell
- ES Lupton
- ET Peterson
- ET Peterson
- EW Thomas
- EW Thomas
- EW Thomas
- EW Thomas
- EW Thomas
- EW Thomas
- F Bilger
- F Plotke
- F Plotke
- FR Schmidt
- FR Selbie
- FW Chorpenning
- FW Reynolds
- G D’alessandro
- G Vryonis
- GE Parkhurst
- GLM McElligott
- Goonwtn
- GR Baler
- GW Stout
- GW Stout
- GX Schwemlein
- GX Schwemlein
- H Beerman
- H Eagle
- H Eagle
- H Eagle
- H Eagle
- H Eagle
- H Eagle
- H Neurath
- H Pariser
- H Pariser
- H Pariser
- H Pariser
- H Schmidt
- H Schmidt
- H Wassermann
- HA Tucker
- HA Tucker
- HA Tucker
- HA Tucker
- HA Tucker
- HC Aron
- HC Gjessing
- HE Morton
- HE Morton
- HJ Greene
- HJ Magnuson
- HJ Magnuson
- HJ Magnuson
- HJ Magnuson
- HJ Magnuson
- HJ Magnuson
- HM Robinson
- HM Robinson
- HM Robinson
- HM Robinson
- HM Robinson
- HM Soloway
- HN Bossak
- HN Cole
- HN Cole
- HN Cole
- HW Kendell
- I Pisu
- IA Kellock
- IJ Orsós
- IL Schamberg
- IN Price
- IN Price
- IN Price
- IW Kuhl
- J Desneux
- J Portnoy
- J Portnoy
- J Rodriquez
- J Rodriquez
- J Rodriquez
- J Rodriquez
- J Rosselot
- J Towpix
- J Yampolsky
- JA Kolmer
- JA Kolmer
- JA Lee
- JB Cross
- JC Booth
- JC Cutler
- JE Kemp
- JE Kemp
- JE Kemp
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JE Moore
- JF Mahoney
- JF Mahoney
- JF O’brien
- JH Bruijn
- JH Stokes
- JH Stokes
- JH Watson
- JJ Andljar
- JK Mason
- JL Miller
- JL Miller
- JL Miller
- JL Miller
- JR Bradfield
- JR Haserick
- JR Heller
- JV Klauder
- JW Lentz
- L Chargin
- L Chargin
- L Friedman
- L Goldman
- L Tuft
- LJ Klinobeil
- LV Dill
- LV Shaffer
- LV Shaffer
- LW Harrison
- LW Harrison
- LW Harrison
- LW Harrison
- LW Harrison
- LW Shaffer
- M Brodey
- M Tottie
- MA Mazzini
- MC Cumberland
- MC Pangrorn
- MD Speiser
- MD Speiser
- MJ Romansky
- MJ Romansky
- MJ Romansky
- MJ Romansky
- ML Davis
- ML Niedielman
- MM Ravitch
- MS Goodwin
- MT Hoekenga
- N Hardy
- N Jones
- NP Sherwood
- NR Ingraham
- NR Ingraham
- NR Rose
- O Bloch
- O Idsoe
- OF Agee
- O’Leary
- O’Leary
- P Durel
- PA O’leary
- PD Graciansky
- PD Rosahn
- PD Rosahn
- PD Rosahn
- PD Rosahn
- PD Rosahn
- PH Hardy
- PJ Pesare
- PJ Sequeira
- Price
- Puccinelli
- PV Koshewnikov
- R Cares
- R Degos
- R. R. Willcox
- RA Boak
- RA Boak
- RA Boak
- RA Fisken
- RA Kern
- RA Nelson
- RA Nelson
- RA Nelson
- RA Nelson
- RA Nelson
- RA Nelson
- RA Nelson
- RA Nelson
- RA Vonderlehr
- RC Arnold
- RC Robinson
- RD Catterall
- RD Hahn
- RD Smions
- RE Campbell
- RH Buckinger
- RH Furman
- RH Laun
- RH Swain
- RH Wiggall
- RL Kahn
- RL Kahn
- RL Kahn
- RL Kahn
- RM Cain
- RM Craig
- RM Smith
- RoDRIQUEZ
- RR Willcos
- RR Willcox
- RR Willcox
- RV Rajam
- RV Rider
- RW Jones
- S Hirschfeld
- S Irgang
- S Irgang
- S Levitan
- S Mudd
- S Olansky
- S Olansky
- S Olansky
- S Olansky
- S Olansky
- S Shaw
- S Weinstein
- SJ Klein
- SJ Klein
- SJ Klein
- SM Feinberg
- SR Taggart
- Stout
- T Guthe
- T Putronen
- T Tuno
- T. F. Probey
- Taggart
- TB Turner
- TB Turner
- TB Turner
- TB Turner
- TB Turner
- TB Turner
- TB Turner
- TB Turner
- TB Turner
- TB Turner
- TB Turner
- TB Turner
- TB Turner
- TF Probey
- TJ Bauer
- TM Vogelsang
- UJ Wile
- UJ Wile
- V Iranzo Prieto
- V Iranzo Prieto
- V Pardocastello
- V Pirila
- V Scott
- VA Puccinelli
- VA Puccinelli
- VA Puccinelli
- VH Falcone
- VM Smith
- VN Tompkins
- W Bickers
- W Fowler
- W Leifer
- WB Dunham
- WB Dunham
- WC Buschemeyer
- WE Herrell
- WE Herrell
- WF Edmundson
- WF Edmundson
- WH Aufranc
- Wilde
- Wilkinson
- WL Eaton
- WM Simpson
- WT Sowder
- Wv Schmerold
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1959
- Field of study
Arsenverbindungen
- Author
- A Albert
- A Albert
- A Bessemans
- A Binz
- A Binz
- A Binz
- A Binz
- A Binz
- A Binz
- A Hauer
- A Michaelis
- A Michaelis
- A New Trypanocidal Agent
- A Schumacher
- A. Bertheim
- A. Tschitschibabin
- AJ Clark
- AL Tatum
- Amide-Substituted Phenylarsineoxides and Their Derivatives
- An experimental study of mapharsen
- Analysis of trypanocidal action of trivalent arsenicals and acriflavine
- Arsenoso compounds containing amide groups.
- Arsine oxides of naphthalene and biphenyl.
- AV Szent-Györgyi
- AW Ruddy
- AW Schwenzer
- BF Skiles
- Bildung aromatischer Arsinsäuren durch Umsetzung von Isodiazokörpern mit Arsenigsäureionen
- Blood levels renal clearance, and chemotherapeutic activity with particular reference to arsenicals and Penicillin. From
- C Binz
- C Verth
- C Voegtlin
- C Voegtlin
- CC Kast
- CC Pfeiffer
- Chemotherapeutica aus der Pyridinreihe
- CK Banks
- CK Banks
- CS Hamilton
- D Balcom
- Derivate des p-Aminophenyl-arsenoxyds
- Die Diazosynthese aromatischer Arsinsäuren und ihre theoretische Deutung im Zusammenhang mit ähnlichen Reaktionen. Ein arsenhaltiges Nebenprodukt
- E Binder
- E Domanig
- E Fourneau
- E Fourneau
- E Friedberger
- E Maschmann
- E Singer
- EAH Friedheim
- Effects of organic arsenicals on enzyme systems
- EM Lotjrie
- ESG Barron
- ESG Barron
- ESG Barron
- EW Schwedt
- F Fölsch
- F Hawking
- FJ Eichenlaub
- FW Schueler
- G Chen
- G Chen
- G Chen
- G Doak
- G Giemsa
- G Giemsa
- G Newbery
- G Schulz
- Gartmann
- GO Doak
- GT Morgan
- GW Raiziss
- GW Raiziss
- H Bart
- H Bergmann
- H Burton
- H Commandon
- H Eagle
- H Eagle
- H Eagle
- H Eagle
- H Eagle
- H Eagle
- H Eagle
- H Fischer
- H Hüllstrung
- H King
- H King
- H Schlossberger
- H Schmidt
- H Schmidt
- H Schwalm
- H Schwietzer
- H Stadler
- H. Eagle
- HA Kühner
- HC Brown
- Herzog
- HH Anderson
- HH Fox
- HJ Barber
- HJ Bielig
- HN Wright
- HO Calvery
- II
- III
- J Brock
- J Garda
- J Traube
- JA Kolmer
- JC Broom
- JD Capps
- JE Balaban
- JE Balaban
- JF Oneto
- JF Schamberg
- JF Schamberg
- JH Stokes
- JJ Gordon
- JW Orth
- K Banck
- K Greber
- K Ogden
- K-H Schmidt
- Kann eine Transfusionssyphilis durch chemotherapeutische Mittel verhindert werden?
- Kataphoreseversuche an Kleinlebewesen. Studien über Eiweißreaktionen. 111
- L Arzt
- L Benda
- L Hellermann
- L Rausch
- L Reiner
- LA Stocken
- LA Stocken
- LD Fink
- M Barrowcliff
- M Krijspe
- M Nomoto
- M Rothermund
- ME Fourneau
- MJ Thuret
- ML Ktjhs
- Neue Problemstellung der Immunbiologie
- NV Jancso
- NV Jancsö
- O Wagner
- Oberflächenstrukturen von Mikroorganismen und ihre Beziehung zu chemotherapeutischen und serologischen Phänomenen
- OM Grtjhzit
- P Dahr
- P Dahr
- P Ehrlich
- P Ehrlich
- P Karrer
- P Organesjan
- P Uhlenhut
- PB Marshall
- PGF Vermast
- Quantitative studies in chemotherapy. III
- R Fussgänger
- R Höber
- R Kapeller-Adler
- R Labes
- R Otto
- R Prigge
- R Prigge
- R Weidenhagen
- R Weidenhagen
- RA Peters
- RA Peters
- RB Hogan
- Reactions of British
- RH Slater
- RJ Schnitzer
- RJ Schnitzer
- S Mutermilch
- SM Rosenthal
- SM Rosenthal
- SM Rosenthal
- Studies in chemotherapy. V
- Studies in chemotherapy. VIII
- Studies on biological oxidations. XIX
- TB Turner
- TF Probey
- TH Grüneberg
- The Absorption Of 4
- The effect of multiple substituents on the toxicity and treponemicidal activity of phenylarsenoxides
- The preparation of phenylarsenoxides. II
- The preparation of phenylarsenoxides. IV. Disubstituted compounds
- The systemic treatment of 227 case of arsenic poisoning (encephalitis dermatitis, blood dyscrasias, jaundice, fever) with 2,3 dimercaptopropanol (BAL). Amer
- The therapeutic efficacy of phenylarsenoxide in mouse and rabbit trypanosomiasis (tryp. equi- perdum)
- The toxicity
- TJ Wagner
- TS Bersin
- TS Bersin
- Untersuchungen über die Wirkung von Arsenoxyden in vitro
- Untersuchungen über die Wirkung von Spirotrypan bei der experimentellen Kaninchensyphilis
- V Fischl
- V Oberbeck
- VD Whittaker
- Verhütung der Transfusions-Syphilis durch Arsenoxyd
- Verhütung der Transfusionslues durch ein Arsenoxydderivat (Haemosept Hoechst)
- Vorschrift für die staatliche Prixjung der Salvar sanpr aparate. Erlaß des Hessischen Ministers des Inneren
- W Cantrell
- W Kolle
- W Kolle
- W Ltjtzeyer
- W Maassen
- W Roehl
- W Schneider
- W Schäfer
- W Steinkopf
- W Wiese
- W Yorke
- W-H Wagner
- W-H Wagner
- W-H Wagner
- W-H Wagner
- WA Jacobs
- WI Strangeways
- WL Lewis
- WP Herrmann
- WP Herrmann
- WP Herrmann
- Zur Kenntnis aromatischer Arsenverbindungen. X
- Über Arsenverbindungen der Anthrachinonreihe.
- Über den jetzigen Stand der Chemotherapie
- Über die 4-Amino-3-oxyphenyl-arsinsäure und deren Oxydationsprodukte
- Über die Hydrierung des Pyridons und seiner N-Alkylderivate. 15. Mitteilung über Derivate des Pyridins
- Über die Nitrierung der Arsanilsäure
- Über halogenierte p-Amino-phenylarsinsäuren
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1961
- Field of study