62 research outputs found
Non-linear dynamic response of a cable system with a tuned mass damper to stochastic base excitation via equivalent linearization technique
Abstract: Non-linear dynamic model of a cable–mass system with a transverse tuned mass damper is considered. The system is moving in a vertical host structure therefore the cable length varies slowly over time. Under the time-dependent external loads the sway of host structure with low frequencies and high amplitudes can be observed. That yields the base excitation which in turn results in the excitation of a cable system. The original model is governed by a system of non-linear partial differential equations with corresponding boundary conditions defined in a slowly time-variant space domain. To discretise the continuous model the Galerkin method is used. The assumption of the analysis is that the lateral displacements of the cable are coupled with its longitudinal elastic stretching. This brings the quadratic couplings between the longitudinal and transverse modes and cubic nonlinear terms due to the couplings between the transverse modes. To mitigate the dynamic response of the cable in the resonance region the tuned mass damper is applied. The stochastic base excitation, assumed as a narrow-band process mean-square equivalent to the harmonic process, is idealized with the aid of two linear filters: one second-order and one first-order. To determine the stochastic response the equivalent linearization technique is used. Mean values and variances of particular random state variable have been calculated numerically under various operational conditions. The stochastic results have been compared with the deterministic response to a harmonic process base excitation
Association of Typical versus Atypical Antipsychotics with Symptoms and Quality of Life in Schizophrenia
BACKGROUND: Several reports on patients with chronic schizophrenia suggest that atypical versus typical antipsychotics are expected to lead to better quality of life (QOL) and cognitive function. Our aim was to examine the association of chronic treatment with typical or atypical antipsychotics with cognitive function, psychiatric symptoms, QOL, and drug-induced extrapyramidal symptoms in long-hospitalized patients with schizophrenia. METHODOLOGY AND PRINCIPAL FINDINGS: The Hasegawa Dementia Scale-Revised (HDS-R), Brief Psychiatric Rating Scale (BPRS), the Schizophrenia Quality of Life Scale, translated into Japanese (JSQLS), and the Drug-Induced Extrapyramidal Symptoms Scale (DIEPSS) were used to evaluate cognitive function, psychiatric symptoms, QOL, and drug-induced extrapyramidal symptoms. We examined the correlation between the dose of antipsychotics and each measure derived from these psychometric tests. The student t-test was used to compare scores obtained from psychometric tests between patients receiving typical and atypical antipsychotics. Results showed significant correlations between chlorpromazine (CPZ)-equivalent doses of typical antipsychotics and atypical antipsychotics, and the total BPRS score and BPRS subscale scores for positive symptoms. CPZ-equivalent doses of typical antipsychotics were correlated with the JSQLS subscale score for dysfunction of psycho-social activity and DIEPSS score. Furthermore, the total BPRS scores, BPRS subscale score for positive symptoms, the JSQLS subscale score for dysfunction of psycho-social activity, and the DIEPSS score were significantly higher in patients receiving typical antipsychotics than atypical antipsychotics. CONCLUSION AND SIGNIFICANCE: These findings suggest that long-term administration of typical antipsychotics has an unfavorable association with feelings of difficulties mixing in social situations in patients with chronic schizophrenia
- …